Results 181 to 190 of about 143,588 (347)

Expression of steroid hormone receptors in BRCA1-associated ovarian carcinomas

, 2005
Objective. BRCA1 mutations predispose to cancer in hormone responsive tissues. A predominance of estrogen receptor (ER)-negative breast cancers in BRCA1 mutation carriers and potential interactions between ERα and BRCA1 suggest a link between hormones ...
Byth, Karen, Clarke, Christine, Katzenellenbogen, Benita, Clarke, Christine L., Katzenellenbogen, Benita S., Russell, Pamela J., Tucker, Katherine M., Edwards, Lyndal, Tucker, Katherine, de Fazio, Anna, Friedlander, Michael, Russell, Pamela, Aghmesheh, Morteza   +12 more
core   +1 more source

Management of Advanced Prostate Cancer in the Asia‐Pacific Region: Summary of the Asia‐Pacific Advanced Prostate Cancer Symposium 2025

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Summary of the Asia Pacific Advanced Prostate Cancer Symposium 2025, showing disciplines and diversity of participants, discussion topics (high‐risk localized/locally advanced prostate cancer; PSA persistence and recurrence; radioligand therapy; genetics and genomics; bone protection and other aspects of supportive care), key themes, and high‐level ...
Edmund Chiong, Renu Eapen, Nicholas Buchan, Kenneth Chen, Lukman Hakim, Agus Rizal Hamid, Jae‐Young Joung, Ravindran Kanesvaran, Makarand Khochikar, Jason Letran, Bannakij Lojanapiwat, Indranil Mallick, Chi Fai Ng, Pei Ing Ngam, Teng Aik Ong, Jacob Pang, Darren M. C. Poon, Natasha Roberts, Marniza Saad, Shinichi Sakamoto, Jeremy Tey, Sue Ping Thang, Poh Choo Toh, Levent Türkeri, Nguyễn Tuấn Vinh, Alvin Wong, Yao Zhu, ANZUP Cancer Trials Group, Ian D. Davis   +28 more
wiley   +1 more source

Rapid screening by Surveyor Nuclease-based mutation detection for BRCA1 and BRCA2 genes

, 2009
Twenty-three percent of first diagnosed breast cancer patients resulted to be candidate for BRCA genetic test and, among these, BRCA1 and BRCA2 mutations occur in almost 20% patients. BRCA testing is complicated by the large gene region and the extent of
B. Pilato, M. Martinucci, SALVATORE, FRANCESCO, P. Zaccagna, M. Iorio, S. Papadimitriou, A. Paradiso, S. Tommasi, FRISSO, GIULIA   +8 more
core  

Systemic Therapy Management Strategies for Early‐Stage Breast Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Advances in systemic therapy for early‐stage breast cancer in Australia highlight genomic‐guided decisions, subtype‐specific strategies, and emerging targeted and immunotherapies, shaping personalized and de‐escalated treatment approaches. ABSTRACT Breast cancer is the most common cancer among Australian women, with early‐stage disease (Stages I, II ...
Nicholas Zdenkowski, Rachel Dear, Sanjeev Kumar, Hilary Martin, Dhanusha Sabanathan, Stephen J. Luen, Belinda Yeo   +6 more
wiley   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Genetic epidemiology of breast cancer in CYPRUS: A case -control study of DNA repair genes [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The occurrence of early-onset breast cancer (EOBC) has been associated with germline mutations in the BRCA1 and BRCA2 genes.
Loizidou, Maria, Liozidou, Maria
core  

Breast Angiosarcoma: 15‐Years Experience

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Breast angiosarcoma is a rare, aggressive malignancy that can be primary (PAS) or secondary (SAS). This study evaluates the management and outcomes of breast angiosarcoma in a single‐center breast/surgical oncology unit. Methods A retrospective review was conducted on patients with histologically confirmed PAS or SAS who underwent ...
Gaik Si Quah, Christopher Pyke, Christopher Allan   +2 more
wiley   +1 more source

SYK expression level distinguishes control from BRCA1-mutated lymphocytes

, 2018
Tamar Zahavi,1,2,* Amir Sonnenblick,1,3,* Yael Shimshon,2 Luna Kadouri,1 Tamar Peretz,1 Asher Y Salmon,1,* Mali Salmon-Divon,2,* 1Sharett Institute of Oncology, Hadassah Hebrew University Medical Center, Jerusalem, Israel; 2Genomic Bioinformatics ...
Peretz T, Salmon-Divon M, Sonnenblick A, Kadouri L, Zahavi T, Salmon AY, Shimshon Y   +6 more
core  

Information Discrimination and Its Implications on Distributing Healthcare Costs Fairly

Bioethics, EarlyView.
ABSTRACT When healthcare resources are scarce, they ought to be distributed fairly across society. For some theories of distribution, an assessment of individual health risk is required for a fair distribution of both healthcare resources and burdens. Despite this requirement, prevailing theories underappreciate the cost of information on health risk ...
Harisan U. Nasir
wiley   +1 more source

The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews.

New England Journal of Medicine, 1997
J. Struewing, P. Hartge, S. Wacholder, S. M. Baker, M. Berlin, M. McAdams, Michelle M. Timmerman, L. Brody, Margaret A. Tucker   +8 more
semanticscholar   +1 more source