Results 171 to 180 of about 111,950 (304)

The ¹H, ¹⁵N and ¹³C backbone resonance assignments of an intrinsically disordered region (467-696) of breast cancer type 1 susceptibility protein (BRCA1). [PDF]

Biomol NMR Assign
Dinh HH, Jasper AM, Baudin A, Sung P, Libich DS.   +4 more
europepmc   +1 more source

Staying in the Unknown: Avoidance of Genetic Testing in Families With Hereditary Cancer Syndromes—A Qualitative Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To explore the experiences and challenges associated with genetic testing decisions among untested individuals from hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) families. Design Qualitative descriptive study. Methods Semi‐structured telephone interviews were conducted between 2022 and 2024 with 56 untested at‐risk ...
Ronit G. Tsemach, Elizabeth E. Half, Hagit Baris‐Feldman, Anastasia Weis, Sharon Simchoni, Sue Kim, Maria C. Katapodi, Sivia Barnoy, Efrat Dagan   +8 more
wiley   +1 more source

A Practical Guide to Chromosome Microarray Interpretation for Paediatricians

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Introduction Chromosome microarray (CMA) is a test commonly ordered by general paediatricians. It has diagnostic yield between 10%–15% in individuals with neurodevelopmental delay, autism and/or multiple congenital abnormalities. CMA identifies copy number variants (CNV) including deletions and duplications, which may be pathogenic, variants ...
Zachary E. McPherson, Margit Shah, Sarah Josephi‐Taylor, Brieana Dance, Benjamin Nash, Luke St Heaps, Dale Wright, Janette Hayward, Christopher Elliot, Joshua Steadson, Alan Ma   +10 more
wiley   +1 more source

Combination of PARPi and topoisomerase I inhibitors is highly effective in olaparib-resistant ovarian cancer. [PDF]

Exp Hematol Oncol
Chiappa M, Villa V, Sias F, Grasselli C, Sala L, Canesi S, Marabese M, Mason S, Dibitetto D, Fruscio R, Damia G.   +10 more
europepmc   +1 more source

Olaparib‐associated cutaneous vasculitis in a patient with breast cancer

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Marcial Álvarez‐Salafranca, Teresa Puértolas, Adrián Diago, María Carmen Gómez‐Mateo   +3 more
wiley   +1 more source

Generics favor stability

Mind &Language, EarlyView.
Humans seek to predict, explain, and control their environments. Generalizations—like those expressed by “children like candy” and “cigarettes cause cancer”—provide one resource to facilitate these tasks. We develop a proposal tying the acceptability judgments of generics to the psychological functions of generalizations.
Katherine Ritchie, Ny Vasil
wiley   +1 more source

Prognostic and therapeutic implications of BRCA1 and BRCA2 mutations in ovarian cancer. [PDF]

Front Oncol
Pawul W, Opoka P, Dusza A, Blajerski B, Orzelska J, Gierulska N, Kułak K, Tarkowski R.   +7 more
europepmc   +1 more source

Breaking down BRCA1 [PDF]

Nature Genetics, 1994
openaire   +2 more sources

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

A Novel BRCA1 Pathogenic Variant in Tunisian Patient With High Grade Ovarian Cancer: Favorable Therapeutic Response to Olaparib. [PDF]

Cancer Rep (Hoboken)
Ammous-Boukhris N, Abdelmaksoud-Dammak R, Feki A, Khemiri S, Charfi S, Sallemi-Boudawara T, Daoud J, Khanfir A, Gargouri RM.   +8 more
europepmc   +1 more source