A prospective observational study of pancreatic cancer risk in men and women with pathogenic variants in BRCA1 or BRCA2. [PDF]
Grindedal EM +4 more
europepmc +1 more source
Abstract Background Germline pathogenic variants can inform targeted therapy for metastatic prostate cancer (mPC), and improve cancer early detection and risk reduction for family members. Guidelines recommend germline genetic testing be offered to all men with mPC, yet uptake of testing is only 10%–12%. Methods This prospective study enrolled veterans
Bruce Montgomery +18 more
wiley +1 more source
Machine learning prediction of germline <i>BRCA1/2</i> pathogenic variants in patients with ovarian cancer. [PDF]
Innella G +11 more
europepmc +1 more source
Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions [PDF]
Aurélie Catteau +7 more
openalex +1 more source
Pleural Metastasis From Male Breast Cancer: A Case Report
ABSTRACT Male breast cancer (MBC) is a rare disease accounting for less than 1% of breast cancers and for 0.11% of all male malignancies. Despite the fact that the epidemiologic, clinical, and therapeutic literature regarding female breast cancer is well documented, little is known about the features of male breast cancer.
Patrizia Straccia, Esther Diana Rossi
wiley +1 more source
Clinical and Pathological Characteristics and Treatment Implications of <i>BRCA1</i>- and <i>BRCA2</i>-Mutated Breast Cancer in Japanese Patients: A Single-Institution Retrospective Study. [PDF]
Akita Y +6 more
europepmc +1 more source
Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid +7 more
wiley +1 more source
BRCA1: An Unrecognized Modulator of Lineage Plasticity in Basal-like Breast Cancer. [PDF]
Sanawar R, Sengodan SK.
europepmc +1 more source
Our findings indicate that ECG‐EVLP can effectively promote wound healing and the activation of the VEGF/AKT signaling pathway in vitro and in vivo, coupled with the inhibition of the mitochondrial apoptosis pathway in cells following ECG‐EVLP stimulation might be its underlying mechanism.
Yingjie Xiong +10 more
wiley +1 more source

