Clinicopathological Characteristics of Lesions Diagnosed by MRI-Guided Biopsy in <i>BRCA1/2</i> Mutation Carriers. [PDF]
Nagata A +4 more
europepmc +1 more source
EMBRACA: Comparison of efficacy and safety of talazoparib (TALA) and physician's choice of therapy (PCT) in patients (pts) with advanced breast cancer (aBC), a germline BRCA1/2 mutation (gBRCAm), and prior platinum treatment [PDF]
Miguel Martín +11 more
openalex +1 more source
ABSTRACT Background Oropharyngeal squamous cell carcinoma (OPSCC) accounts for a substantial proportion of head and neck cancers, with a rising incidence largely driven by human papillomavirus (HPV) infection. Despite advances in multimodal treatment, disease recurrence remains common and limits long‐term survival, highlighting the need for reliable ...
Yunxia Chen +7 more
wiley +1 more source
RESPONSE: Re: Pretest Prediction of BRCA1 or BRCA2 Mutation by Risk Counselors and the Computer Model BRCAPRO [PDF]
David Euhus
openalex +1 more source
Antiproliferative Effects of Cannabinoids and Cisplatin in Cervical Cancer Cells
ABSTRACT Introduction Cervical cancer remains a leading cause of cancer‐related mortality among women globally, particularly in low‐ and middle‐income countries. Cisplatin, a standard chemotherapeutic agent, is limited by severe toxicities and chemoresistance. This study aimed to assess the effects of cisplatin in combination with phytocannabinoids, Δ9‐
S. P. Mathibela +2 more
wiley +1 more source
Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage response
Aparna Gorthi, Alexander J. R. Bishop
doaj +1 more source
Resistance to neoadjuvant talazoparib in triple-negative breast cancer by BRN2-induced ATR/STAT3 pathways or SHLD2 subclone expansion. [PDF]
Abdulkareem NM +14 more
europepmc +1 more source
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu +4 more
wiley +1 more source
BRCA1/2 and CHEK2 Pathogenic Variants in Urological Cancers: A Portuguese Single-Center Experience. [PDF]
Quinto Pereira M +7 more
europepmc +1 more source

