Results 221 to 230 of about 177,994 (348)

EMBRACA: Comparison of efficacy and safety of talazoparib (TALA) and physician's choice of therapy (PCT) in patients (pts) with advanced breast cancer (aBC), a germline BRCA1/2 mutation (gBRCAm), and prior platinum treatment [PDF]

open access: hybrid, 2018
Miguel Martín   +11 more
openalex   +1 more source

Clinical Significance of Biomarkers in Oropharyngeal Squamous Cell Carcinoma: Recurrence Prediction and Treatment Response

open access: yesCancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Oropharyngeal squamous cell carcinoma (OPSCC) accounts for a substantial proportion of head and neck cancers, with a rising incidence largely driven by human papillomavirus (HPV) infection. Despite advances in multimodal treatment, disease recurrence remains common and limits long‐term survival, highlighting the need for reliable ...
Yunxia Chen   +7 more
wiley   +1 more source

Antiproliferative Effects of Cannabinoids and Cisplatin in Cervical Cancer Cells

open access: yesCancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Introduction Cervical cancer remains a leading cause of cancer‐related mortality among women globally, particularly in low‐ and middle‐income countries. Cisplatin, a standard chemotherapeutic agent, is limited by severe toxicities and chemoresistance. This study aimed to assess the effects of cisplatin in combination with phytocannabinoids, Δ9‐
S. P. Mathibela   +2 more
wiley   +1 more source

Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage response

open access: yesMolecular & Cellular Oncology, 2018
Aparna Gorthi, Alexander J. R. Bishop
doaj   +1 more source

Resistance to neoadjuvant talazoparib in triple-negative breast cancer by BRN2-induced ATR/STAT3 pathways or SHLD2 subclone expansion. [PDF]

open access: yesProc Natl Acad Sci U S A
Abdulkareem NM   +14 more
europepmc   +1 more source

Targeting the nuclear export receptor exportin‐1 in acute myeloid leukaemia: From biology to clinical translation

open access: yesClinical and Translational Medicine, Volume 16, Issue 5, May 2026.
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu   +4 more
wiley   +1 more source

BRCA1/2 and CHEK2 Pathogenic Variants in Urological Cancers: A Portuguese Single-Center Experience. [PDF]

open access: yesCureus
Quinto Pereira M   +7 more
europepmc   +1 more source

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