Results 231 to 240 of about 95,123 (282)

From Biobank to Bedside: A Pilot Study on Returning Medically Actionable BRCA1/2 Results in Qatar's Precision Medicine Landscape. [PDF]

Biomedicines
Al Bader SB, Habish H, Almulla H, Abbaszadeh F, Sidenna M, Fadl T, Alvi M, Eldeeb M, Farah H, Elfatih A, Badji RM, Chouchane L, Afifi N, Ismail S, Alsulaiman R, Al-Muftah W.   +15 more
europepmc   +1 more source

Study on the correlation between BRCA1 gene polymorphism and hrHPV infection in cervical precancerous lesions

Dongling He, Qing Lv, Bin Li, Min Xu, Jiang De-wen, Zhi Tang, Yanjie Liu   +6 more
openalex   +1 more source

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

Cell Proliferation, Volume 59, Issue 2, February 2026.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao, Yuting Qiu, Jie Chen, Danni Wang, Zairui Wang, Shuang Ma, Yimin Liu, Guoying Liu, Zhuofei Bi   +8 more
wiley   +1 more source

A BRCT domain-containing protein induced in early phagocytosis plays a crucial role in the pathogenesis of the mucoralean Rhizopus microsporus. [PDF]

PLoS Pathog
Tahiri G, Lax C, Binder U, Scheler J, Navarro E, Nicolás FE, Garre V.   +6 more
europepmc   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy, Raymond Barnhill, Boris C. Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony Gill, Jennelle C. Hodge, Joseph D Khoury, Katia Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Liang Zhiyong, Holger Moch, Rajendra Singh, Harshima Wijesinghe, Ian Cree, Dilani Lokuhetty   +29 more
wiley   +1 more source

Screening, Risk Reduction Strategies, and Clinical Management of Unaffected Carriers of <i>BRCA1</i> or <i>BRCA2</i> Pathogenic Variants. [PDF]

World J Oncol
Abdel-Razeq H, Mansour R.
europepmc   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

HSP90 buffers deleterious genetic variations in BRCA1. [PDF]

Mol Cell
Gracia B, Zhang XH, Montes P, Pham TC, Huang M, Chen J, Karras GI.   +6 more
europepmc   +1 more source

Screening of the founder pathogenic variants BRCA1 and BRCA2 in Russian metropolitan women. [PDF]

BMC Womens Health
Bodunova N, Bilyalov A, Danishevich A, Kvetenadze G, Andronov A, Starshinin A, Rumyantsev K, Zhukova L, Khripun A, Khatkov I.   +9 more
europepmc   +1 more source

BRCA1 and 2 Mutations and Efficacy of Pembrolizumab-Based Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer: A Real-World Multicenter Analysis. [PDF]

J Clin Med
Fedele P, Rizzo A, Landriscina M, Stucci SL, Morritti M, Giuliani F, Moraca L, Cairo G, Ardito R, Giampaglia M, Bilancia D, Melaccio A, Terenzio A, Gnoni A, Licchetta A, Fumai F, Lanotte L, Gadaleta-Caldarola G.   +17 more
europepmc   +1 more source