Results 251 to 260 of about 95,123 (282)

Alteration of Hyaluronic Acid Metabolism in Tumor Microenvironment Can Modulate DNA Repair Gene Expression: Therapeutic Potential for Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Sevic I, Vitale DL, Moran Maidana C, Rosales P, Icardi A, Latina C, Romano L, Brandone A, Giannoni P, Alaniz L.   +9 more
europepmc   +1 more source

Integrative sWGS: A New Paradigm for HRD Detection in Ovarian Cancer. [PDF]

Int J Mol Sci
Jinga DC, Duta-Cornescu G, Cimponeriu D, Papadopoulou E, Meintani A, Tsaousis G, Chirnogea A, Bucatariu I, Iorga PG, Chetroiu D, Hosu SC, Hogea-Zah A, Median MD, Diana B, Stănculeanu DL, Mihaila R, Nagy DS, Motatu PE, Eugeniu T, Cristea EO, Iaciu IC, Kubelac P, Truican A.   +22 more
europepmc   +1 more source

Changes in life decisions and in emotions following genetic testing for cancer risk. [PDF]

BMC Psychol
Durosini I, Ongaro G, Oliveri S, Sebri V, Pravettoni G.   +4 more
europepmc   +1 more source

Clinical implications of rare and common variation in preimplantation genetic testing for breast cancer. [PDF]

NPJ Genom Med
Lencz T, Bhattacharyya U, Klausner L, John J, Carmi S.   +4 more
europepmc   +1 more source

The Role of Aurora Kinase A in HBV-Associated Hepatocellular Carcinomas: A Molecular and Immunohistochemical Study. [PDF]

Diagnostics (Basel)
Huz M, Karadag Soylu N, Koc A, Kucukakcali Z, Danis N, Ozhan O.   +5 more
europepmc   +1 more source

Associations between Pathogenic Germline Variants in BRCA and Non-Breast/Non-Ovarian Cancer Types in the German Population.

Geburtshilfe Frauenheilkd
Zilski N, Roehle R, Stegen S, Blohmer JU, Wagner JK, Speiser D.   +5 more
europepmc   +1 more source

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Brca1 and differentiation

Mutation Research/Reviews in Mutation Research, 2002
Breast cancer is one of the most frequent malignancies affecting women. The human breast cancer gene 1 (BRCA1) gene is mutated in a distinct proportion of hereditary breast and ovarian cancers. Tumourigenesis in individuals with germline BRCA1 mutations requires somatic inactivation of the remaining wild-type allelle. Although, this evidence supports a
Marion, Kubista, Margit, Rosner, Angelina, Miloloza, Katja, Hofer, Andrea-Romana, Prusa, Regina, Kroiss, Erika, Marton, Markus, Hengstschläger   +7 more
openaire   +2 more sources

Perspective on BRCA1

Breast Disease, 1998
In a very real sense, the search for a breast cancer susceptibility gene reflects the rapid evolution of molecular genetics as a field and the power of molecular technology to accelerate the pace of discovery. This search began with the study of blood proteins through biochemical analysis; the number of loci accessible was limited, and very few ...
B, Newman, E T, Liu
openaire   +2 more sources

Identification of BRCA1-IRIS, a BRCA1 locus product

Nature Cell Biology, 2004
Breast cancer is the most common malignancy among women, and mutations in the BRCA genes produce increased susceptibility to these malignancies in certain families. Here we identify BRCA1-IRIS as a 1,399-amino-acid BRCA1 gene product encoded by an uninterrupted open reading frame that extends from codon 1 of the known BRCA1 open reading frame to a ...
Wael M, ElShamy, David M, Livingston
openaire   +2 more sources