Results 271 to 280 of about 143,588 (347)

Prevalence and clinical significance of germline pathogenic variants identified by multigene panel testing in high-risk Japanese patients with breast cancer. [PDF]

Breast Cancer
Kano M, Taruno K, Inuzuka M, Makino R, Takeuchi M, Suzuki M, Kida K, Takei J, Nagayama A, Hayashida T, Haruyama Y, Ueno T, Watanabe C, Kojima Y, Sasai R, Endo M, Momozawa Y, Nakamura S.   +17 more
europepmc   +1 more source

Selective Autophagy Receptor CsNBR1 Confers Citrus Huanglongbing Resistance by Degrading ‘Candidatus Liberibacter Asiaticus’ Virulence Effectors

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
Overexpression of CsNBR1 confers HLB resistance in citrus by degrading CLas effector proteins, including SDE5115, SDE1, SDE19 and SDE5, via the autophagy pathway. ABSTRACT The selective autophagy receptor NEIGHBOUR OF BRCA1 (NBR1) is a key regulator of plant immunity, but its role against bacterial pathogens remains poorly understood.
Yaqian Shi, Xuejin Cui, Fang Fang, Zaiyu Yang, Yalin Mei, Shimian Ma, Changyong Zhou, Xuefeng Wang   +7 more
wiley   +1 more source

A report of novel inactivating missense mutations of BRCA1 detected in patients with acute myeloid leukemia. [PDF]

J Med Case Rep
Ejaz S, Raashid A, Hameed Y, Abdullah I, Imtiaz N, Iqbal M, Khurshid M, Malik WN.   +7 more
europepmc   +1 more source

BRCA1 Gene [PDF]

, 2020
openaire   +1 more source

Prevalence of recurrent and non-recurrent BRCA1 and BRCA2 pathogenic variants in Polish breast cancer patients: insights from a regional genetic testing cohort from Lower Silesia. [PDF]

BMC Cancer
Matkowski R, Abrahamowska M, Michalowska D, Chrusciel A, Szelachowska J, Blomka D, Lawicka P, Czykalko E, Pietron A, Ekiert M, Doraczynska-Kowalik A, Janus-Szymanska G, Kasprzak P, Szynglarewicz B, Laczmanska I.   +14 more
europepmc   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

Breast cancer risk genes affecting individual radiosensitivity. [PDF]

Sci Rep
Vogel RKG, Amann N, Kassem TZ, Gaß P, Mayo T, Woltereck F, Hack CC, Fietkau R, Corradini S, Distel L, Kuhlmann LCF.   +10 more
europepmc   +1 more source

Willingness of Chinese Breast Cancer Patients for Their Children to Undergo <i>BRCA1/2</i> Genetic Testing and Associated Factors. [PDF]

Int J Womens Health
Yu X, Wu M, Liu L, Zhang C.
europepmc   +1 more source

Co-Pathogenic Role of BRCA1 and OBSCN Deletions in Chinese Familial Breast Cancer: A Case Report. [PDF]

Am J Case Rep
Yi L, Chen K, Wang D, Wang R, Zhu X, Chai J, Jia X, Xu F, Gu M, Cui C, Zhang W.   +10 more
europepmc   +1 more source