Results 61 to 70 of about 111,950 (304)
SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin +17 morewiley +1 more sourceFertility preservation in women with BRCA1/2‑related cancers: contemporary strategies, international recommendations, and a multidisciplinary approach
Южно-Российский онкологический журналInherited mutations in the BRCA1/BRCA2 genes significantly increase the risk of breast and ovarian cancer in women of reproductive age, posing a clinical and socioeconomic challenge due to loss of fertility during cancer treatment and preventive ...S. I. Mikhailov, E. G. Novikova, D. Sh. Dzhabrailova, I. M. Onofriychuk, E. K. Saribekian, A. S. Zolotukhina, M. A. Revkova, P. A. Shatalov, K. V. Maksimov, N. V. Ablitsovа, F. S. Khugaeva, I. S. Duadze, V. V. Efanov, N. D. Zamaldinov, E. A. Lisitsyna, A. D. Zikiryakhodzhaev +15 moredoaj +1 more sourceTP53 loss initiates chromosomal instability in fallopian tube epithelial cells
Disease Models & Mechanisms, 2021 High-grade serous ovarian cancer (HGSOC) originates in the fallopian tube epithelium and is characterized by ubiquitous TP53 mutation and extensive chromosomal instability (CIN).Daniel Bronder, Anthony Tighe, Darawalee Wangsa, Dali Zong, Thomas J. Meyer, René Wardenaar, Paul Minshall, Daniela Hirsch, Kerstin Heselmeyer-Haddad, Louisa Nelson, Diana Spierings, Joanne C. McGrail, Maggie Cam, André Nussenzweig, Floris Foijer, Thomas Ried, Stephen S. Taylor +16 moredoaj +1 more sourceTreatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran +6 morewiley +1 more sourceSpectrum of pathogenic variants associated with hereditary breast and ovarian cancer in the Republic of Dagestan
Сибирский онкологический журналBackground. A significant proportion of patients with breast cancer (BC) and ovarian cancer (OC) are carriers of pathogenic variants in the genes of hereditary cancer syndromes. Most often, hereditary forms of BC and OC are associated with alterations in M. M. Ibragimbekova, M. A. Murachuev, G. A. Yanus, B. N. Buttaeva, A. A. Romanko, A. E. Lomakova, E. V. Belogubova, E. V. Preobrazhenskaya, M. V. Syomina, E. N. Suspitsin, A. P. Sokolenko, E. N. Imyanitov +11 moredoaj +1 more sourceBreast cancer risk and 6q22.33: combined results from breast cancer association consortium and consortium of investigators on modifiers of BRCA1/2 [PDF]
, 2012 Recently, a locus on chromosome 6q22.33 (rs2180341) was reported to be associated with increased breast cancer risk in the Ashkenazi Jewish (AJ) population, and this association was also observed in populations of non-AJ European ancestry. In the present Schürmann, Peter, Reed, M.W.R. (Malcolm), Noh, D-Y., Beesley, Jonathan, Severi, G., Hillemanns, Peter, Gold, B., G. E. M. Ausems, Margreet,, Ute Hamann (89879), Rookus, M.A., SWE-BRCA, Schuermann, Peter, Seal, Sheila, Lambrechts, Diether,, C. Southey, Melissa, Douglas, F., Schürmann, P. (Peter), Maria A Caligo, Hsiung, C-N., Frans B L Hogervorst, Wachenfeldt, A. (Anna) von, Natalia Antonenkova, Stig E Bojesen, Kosma, V.M., Mannermaa, Arto,, Pilar Zamora, M., Meindl, A., AOCS Study Grp, Heli Nevanlinna, Van Dorpe, Thijs, Anne-Sophie Dieudonne, B. Gomez Garcia, Encarna,, Schmidt, Marjanka K., Keun-Young Yoo, Couch, F.J. (Fergus), Georgia Chenevix-Trench (361), Lindor, Noralane,, Chang Claude, Jenny, Milne, R.L. (Roger), Melin, Beatrice,, Lambrechts, D., John L Hopper, Burwinkel, Barbara,, Brock, I.W. (Ian), Vachon, C., Broeks, A., Hopper, JL, D. P. Pharoah, Paul, van Asperen, Christi J., Aalfs, C.M. (Cora), Bogdanova, Natalia,, Douglas, F. (Fiona), Zachary Fredericksen (146612), Renwick, Anthony,, A. Agnarsson, Bjarni, Hatse, Sigrid,, Tollenaar, Robert A. E. M., John L. Hopper (89919), Jenny Chang-Claude (23562), D. Gareth Evans (154186), SWE-BRCA (154081), Hsiung, Chia-Ni, Loman, N. (Niklas), M. Braaf, Linde,, Gille, H.J.P. (Hans), Benitez, Javier,, A. Oldenburg, Rogier,, Verheus, Martijn, Linde M. Braaf (153949), Kataja, V, Paul D P Pharoah, Veli-Matti Kosma, Elliott, Graeme, Gille, Hans J. P., Yoo, K.-Y., Prokofieva, Daria, H. Karstens, Johann, Evans, D.G. (Gareth), J. Couch, Fergus,, Lorna Gibson, Benítez, J. (Javier), Gaudet, Mia M.,, Yu, JC, Ian Brock (153910), Van Dorpe, T., Pharoah, P.D., Bojesen, S.E., Hooning, MJ, Gómez García, EB, Braaf, L.M. (Linde), Kosma, V.-M., Lindblom, A., Ko, Yon-Dschun,, Spurdle, Amanda B, Ong, KR, Sei-Hyun Ahn, Kang, D., Wu, P-E., Johnson, N, Bermisheva, M., Yu, Jyh-Cherng,, Carol Chu, Yu, J., Wijnen, JT, Kauppinen, J, Frans B. L. Hogervorst (146390), Margreet G E M Ausems, Ko, Yon-Dschun, Ahn, Sei-Hyun,, Nordestgaard, B.G., Johann H Karstens, Karstens, Johann H., et al., Vachon, C, Van 't Veer, LJ, Anna von Wachenfeldt, Fredericksen, Z, Group, AOCS Study, Milne, R.L., Eeles, R., Hopper, J.L., Cox, A, G. Giles, Graham, Shen, C-Y., Hillemanns, P., Godwin, AK, Thilo Dörk (89882), Rabstein, S. (Sylvia), Bojesen, Stig E., Lesley McGuffog (153865), Paul D.P. Pharoah (154191), Holland, Helene,, Peock, Susan,, Dork, T., Milne, Roger L, Pharoah, P.D.P., Brauch, H, Mannermaa, A. (Arto), Reed, M.W.R., Tuomas Heikkinen (146567), Cox, Angela, Olson, J, Chu, Carol,, F. Easton, Douglas,, Olivia Fletcher, I. Rogov, Juri,, Davidson, R., Group, A.S., Mia M. Gaudet (146621), Sigrid Hatse (12560), Chu, C. (Carol), K. Godwin, Andrew,, Ian Brock, Luccarini, Craig, Johnson, Nichola, Wang, X. (Xianshu), Ausems, Margreet G.E.M., Giles, GG, Daria Prokofieva (154021), Sue Healey, Antonenkova, N, Cook, Margaret, Aalfs, CM, BCAC-CIMBA, Yu, J-C., Douglas, Fiona,, Peter Devilee (13431), Lindblom, Annika, Oldenburg, Rogier A, Annika Lindblom, Asperen, C.J. van, Vesa Kataja (89896), Baglietto, L, Bermisheva, Marina, Humphreys, Manjeet K., Ligtenberg, Marjolijn J., Justenhoven, C. (Christina), Xiaoqing Chen, Dieudonne, Anne Sophie, Kirchhoff, T., Gaudet, Mia M., Flyger, Henrik,, Braaf, Linde M., Hodgson, Shirley,, Zamora, M Pilar, Luccarini, C, M. Domchek, Susan,, Fletcher, O. (Olivia), Godwin, Andrew K, Broeks, A. (Annegien), Angela Cox (76913), Dork, Thilo,, Meindl, A, Kataja, V. (Vesa), Severi, G, Oldenburg, R.A., Brauch, H., Dunning, A.M. (Alison), Reed, Malcolm W. R., Gibson, L., Burwinkel, B., Susan Peock (154155), Dieudonné, A.-S. (Anne-Sophie), Hsiung, Chia Ni, Lambrechts, Diether, Gille, H.J., Bojesen, SE, Marina Bermisheva, Benítez, J., Kircchoff, T. (Tomas), Hamann, U. (Ute), Carol Chu (154167), Evans, Gareth; id_orcid, Javier Benítez, L. Hopper, John,, Hammet, F. (Fleur), Severi, G. (Gianluca), Giles, Graham G, Noh, DY, Prokofieva, Daria,, Chu, C., Dieudonne, AS, Prokofieva, D, Craig Luccarini (10535), Tomas Kirchhoff (102401), M. Aalfs, Cora,, Southey, Melissa C., Gaudet, MM, Fredericksen, Z., Oliver, C.T., Stig E. Bojesen (89870), Fletcher, Olivia,, Milne, RL, Loman, Niklas,, Marjolijn J. Ligtenberg (154122), M. Braaf, Linde, Antonenkova, N.N. (Natalia), Antoniou, A.C. (Antonis), Yoo, Keun-Young, Peock, S. (Susan), Braaf, L.M., Graham G. Giles (89916), Domchek, SM, Gómez García, Encarna B., Milne, Roger L., Douglas F. Easton (89956), Easton, Douglas F., Melissa C Southey, Diether Lambrechts (101772), Khusnutdinova, Elza,, Andrulis, I.L. (Irene), Caligo, MA, Ausems, M.G., Wang, X.S., Giles, G.G., Heikinen, T. (Tuomas), Hogervorst, F.B., Reed, MW, Hooning, Maartje J, Rahman, N, Beesley, Jonathan,, Humphreys, M.K. (Manjeet), Helene Holland, Peto, J., Craig Luccarini, Rookus, MA, Chen, Xiaoqing,, Hillemanns, P, Seynaeve, C.M. (Caroline), Nazneen Rahman, Gille, Hans JP, Tollenaar, R.A.E.M. (Rob), Pharoah, Paul D. P., Van 't Veer, L.J., Shen, CY, Garcia, E.B.G., Vesa Kataja, Dörk, T. (Thilo), Chenevix Trench, Georgia, Oliver, C.T. (Clare), Gille, Hans J P, Xiaoqing Chen (89898), Eccles, Diana,, Ahn, S.-H. (Sei-Hyun), Veer, L.J. van 't, Hogervorst, Frans B L, Caligo, Maria A, Meindl, Alfons,, Domchek, S.M., Noh, Dong-Young,, Margaret Cook (154156), Yu, J.-C., H. Karstens, Johann,, Devilee, Peter,, Gaudet, M.M., McGuffog, L. (Lesley), J. van Asperen, Christi,, Elliott, Graeme,, Jyh-Cherng Yu, Kirchhoff, T, Fergus J Couch, J. van Asperen, Christi, Bert Gold, Margolin, Sara, Alison M. Dunning (146796), Frost, D., Hopper, John L., Hamann, U, Hogervorst, Frans B. L., Antoniou, AC, Rosemarie Davidson, EMBRACE, BCAC-CIMBA, HEBON, AOCS Study Grp, kConFab, GENICA Network, SWE-BRCA, Van ‘t Veer, Laura J., Schuermann, Peter,, Davidson, R, L. Hopper, John, Luccarini, C. (Craig), Shan Wang-Gohrke (89910), Offit, K, Frost, D, Cook, J., Wang, XS, Wang, Xianshu, Peock, Susan, Gold, Bert, Khusnutdinova, E., Gille, J.J.P., Dorpe, T. (Thijs) van, Robert A.E.M. Tollenaar (154029), Dork, Thilo, Aalfs, Cora M., Cox, A. (Angela), Schuermann, P., Dieudonne, Anne-Sophie,, Ong, Kai-Ren, Yu, J-C. (Jyh-Cherng), Hammet, F., Kataja, Vesa, Turnbull, C. (Clare), van Asperen, CJ, Wu, Pei-Ei, Gibson, L.J. (Lorna), Beesley, J. (Jonathan), Nathanson, K.L. (Katherine), Noh, D.H., Rogier A. Oldenburg (154114), Henrik Flyger (146491), Wang, X, Dunning, Alison M, Baglietto, L. (Laura), Rogier A Oldenburg, Heikkinen, T., Wang, Xianshu,, Gareth Evans, D., Burwinkel, B, Broeks, A, Juul T Wijnen, B. Spurdle, Amanda,, Antonenkova, N., Tollenaar, RAEM, Cook, M., Pichert, G., Hamann, Ute, Kosma, Veli-Matti, Nordestgaard, Borge G.,, Agnarsson, B.A. (Bjarni), Askmalm, M.S., Turnbull, Clare,, Margolin, S. (Sara), Ausems, MG, Godwin, A.K. (Andrew), McGuffog, L., Tomas Kirchhoff, Jaana Kauppinen, Braaf, LM, Kirchhoff, Tomas,, Frost, Debra, Humphreys, MK, Pharoah, Paul DP, Harth, V. (Volker), Oliver, Clare T, Thijs Van Dorpe, Chang-Claude, J, J. P. Gille, Hans, Natalia Bogdanova, Kauppinen, Jaana, Cox, Angela,, Natalia Bogdanova (89885), Annegien Broeks, Marie Stenmark Askmalm (154086), Noh, D-Y. (Dong-Young), A. E. M. Tollenaar, Robert,, Caroline Seynaeve, Pesch, B. (Beate), Rookus, M.A. (Matti), Rahman, N., D. P. Pharoah, Paul,, Bojesen, Stig E, Natalia Antonenkova (154010), Anthony Renwick, Hooning, Maartje, Grp, AOCSS, Van Dorpe, Thijs,, Network, GENICA, Peto, J, Oldenburg, Rogier, Reed, Malcolm WR, T. Wijnen, Juul,, Severi, Gianluca,, Rosalind Eeles (154187), Karlsson, Per,, Fredericksen, Z. (Zachary), Johnson, N. (Nichola), Juri I Rogov, Julian Peto, Hogervorst, FB, Hooning, M.J. (Maartje), Melin, B, Susan M Domchek, Daria Prokofieva, Ligtenberg, M.J., G. E. M. Ausems, Margreet, Garcia, Encarna B. Gomez, Sheila Seal (146516), A. E. M. Tollenaar, Robert, Daehee Kang, Wu, Pei Ei, Shen, Chen-Yang,, Yoo, K.Y., Arias, JI, Graeme Elliott, Devilee, P, Encarna B Gómez García, José Ignacio Arias, Jackie Cook, Melissa C. Southey (89921), Clare T Oliver, Karlsson, P., Ong, K.R., A. Oldenburg, Rogier, Nordestgaard, BG, Wijnen, J.T., Sue Healey (41187), Meindl, Alfons, J. Ligtenberg, Marjolijn, Brock, Ian,, Hatse, S, Arto Mannermaa, L. Nathanson, Katherine,, Martijn Verheus, Margolin, S., Pichert, G, Heikkinen, Tuomas, Ko, Yon Dschun, Fletcher, O., Flyger, H., Bogdanova, Natalia, Kauppinen, J. (Jaana), Dieudonne, A.S., Ahn, Sei Hyun, Healey, S, Anne-Sophie Dieudonne (154000), Zamora, MP, Chen, Xiaoqing, Zamora, M.P. (Pilar), Jackie Cook (154176), Hillemanns, P. (Peter), Johann H. Karstens (146565), EMBRACE, Elliott, G, J. Van t Veer, Laura, Nevanlinna, H., Ahn, S.H., Daehee Kang (6451), Elza Khusnutdinova (146583), Nathanson, Katherine L, von Wachenfeldt, Anna, McGuffog, Lesley, M. Pilar Zamora (146494), van 't Veer, LJ (Laura), Rogov, JI, Kosma, VM, Yoo, Keun Young, Pharoah, Paul D P, kConFab (154048), Gold, Bert,, Shan Wang-Gohrke, M. Domchek, Susan, Dieudonne, A.-S., Xianshu Wang (146610), Matti A Rookus, Rabstein, S, Van ‘t Veer, Laura J, Nordestgaard, Borge G., Maartje J. Hooning (89934), Antoniou, A.C., Heikkinen, Tuomas,, Dong-Young Noh, AOCS Study Group, Holland, H. (Helene), Bert Gold (17043), Margolin, Sara,, Fletcher, Olivia, Eeles, Rosalind,, Seal, Sheila,, Wu, P.-E. (Pei-Ei), Pesch, B, Rahman, N. (Nazneen), Andrulis, IL, T. Oliver, Clare, Ko, Y-D., Pei-Ei Wu (153976), Ignacio Arias, Jose, Caroline Seynaeve (95368), Elza Khusnutdinova, Brüning, T. (Thomas), Stenmark Askmalm, Marie, L. Milne, Roger, A. Rookus, Matti, Chen, XQ, Gold, B, Mannermaa, A, Ko, Y-D. (Yon-Dschun), Gille, Hans J.P., EMBRACE (154152), Tollenaar, R.A.E.M., Ausems, Margreet GEM, Noh, Dong Young, Gille, HJP, Dieudonne, Anne-Sophie, Nevanlinna, H, Khusnutdinova, E, Caligo, M.A. (Maria), Kosma, Veli Matti, Marjolijn J Ligtenberg, Nevanlinna, H. (Heli), Niklas Loman (26096), Agnarsson, Bjarni A, Peter Hillemanns, Gianluca Severi (89918), Loman, N., Seynaeve, C, Chen, X., Katherine L Nathanson, Maria A. Caligo (154069), Van 't Veer, Laura J., Easton, D.F., Chang-Claude, Jenny, Per Karlsson, Godwin, Andrew K., L. Andrulis, Irene, Turnbull, C, Niklas Loman, Chenevix-Trench, G., Jaana Kauppinen (154064), Ausems, MGEM, Ligtenberg, M.J. (Marjolijn), Ausems, Margreet G. E. M., Manjeet K Humphreys, Marie Stenmark Askmalm, Schmidt, MK, Justenhoven, C, Zamora, M. Pilar, Van Dorpe, T, Hatse, S., Bjarni A Agnarsson, Gille, HJ, Healey, S. (Sue), Seynaeve, C., Kenneth Offit (63812), Cook, Margaret,, Ausems, M.G.E.M., Dong-Young Noh (6456), Couch, Fergus J, Shen, C.Y., Wang Gohrke, Shan, Gibson, Lorna,, Garcia, EBG, W. R. Reed, Malcolm,, Cora M Aalfs, Andrulis, Irene L, Antonenkova, Natalia,, Broeks, Annegien, Rogov, J.I. (Juri), Kang, Daehee, Chia-Ni Hsiung, B. L. Hogervorst, Frans,, Wang-Gohrke, Shan, Asperen, C.J. (Christi) van, Zachary Fredericksen, Janet Olson, Douglas, F, A. Caligo, Maria, Christi J van Asperen, Hsiung, C.-N., Børge G. Nordestgaard (89871), Dunning, A.M., Frost, Debra,, Debra Frost (154160), Yon-Dschun Ko (89880), Hammet, F, Braaf, Linde M, Hatse, S. (Sigrid), Harth, V, Noh, D.-Y., Jenny Chang-Claude, Gabriella Pichert, Verheus, M, Giles, Graham G., Georgia Chenevix-Trench, Nichola Johnson (146445), Fletcher, O, Lindblom, A. (Annika), Christi J. van Asperen (89901), Matti A. Rookus (154108), Kauppinen, Jaana,, Noh, D.Y., Gibson, Lorna, Offit, Kenneth, Andrew K. Godwin (131285), Debra Frost, Annegien Broeks (146385), Anna von Wachenfeldt (154090), Gille, H.J.P., Pharoah, Paul D.P., Linde M Braaf, Barbara Burwinkel (146479), Schürmann, P., Wang-Gohrke, S., Hsiung, C.N., Johnson, N., Ausems, M.G.E.M. (Margreet), Holland, H., Spurdle, Amanda B., Evans, D Gareth, Ligtenberg, Marjolijn J, Spurdle, AB, Flyger, Henrik, Pilar Zamora, M, Nordestgaard, Børge G., Domchek, S.M. (Susan), Diana Eccles, Irene L. Andrulis (107262), Gabriella Pichert (69450), Evans, DG, Kosma, V-M., Celine Vachon, Hogervorst, F.B.L. (Frans), Davidson, Rosemarie,, Tollenaar, Robert A E M, W. R. Reed, Malcolm, Julian Peto (146454), Gómez García, E.B., Hamann, Ute,, Encarna B. Gómez García (154147), Kataja, Vesa,, Rabstein, Sylvia, Agnarsson, Bjarni A., Shen, C.-Y., Ahn, Sei-Hyun, Wu, PE, Davidson, R. (Rosemarie), Ong, K.-R., Keun-Young Yoo (127429), HEBON (154096), Bogdanova, N, Melin, Beatrice, Hodgson, Shirley, Lesley McGuffog, Shirley Hodgson, T. Wijnen, Juul, A. Rookus, Matti,, Offit, Kenneth,, Robert A E M Tollenaar, Antoniou, Antonis C, Shirley Hodgson (154183), Askmalm, Marie Stenmark, Bermisheva, Marina,, Diana Eccles (154169), Andrew K Godwin, Hogervorst, FBL, Laura Baglietto, Eccles, D., Oliver, CT, Nichola Johnson, Wang-Gohrke, S, Ignacio Arias, J., Gaudet, Mia M, Hooning, Maartje J., Rogov, Juri I, Humphreys, Manjeet K, Katherine L. Nathanson (154077), K. Godwin, Andrew, Vachon, Celine,, Chang-Claude, J. (Jenny), Brock, I, Reed, Malcolm W.R., Per Karlsson (48671), Kenneth Offit, Børge G Nordestgaard, Evans, D. Gareth, Hsiung, CN, Hogervorst, Frans BL, Eccles, D, Nazneen Rahman (146509), Jonathan Beesley, Alfons Meindl (112058), Ong, Kai Ren, Peto, Julian, Susan M. Domchek (154078), Renwick, A., Turnbull, Clare, Peter Schürmann (89883), Luccarini, Craig,, Renwick, A. (Anthony), Pilar Zamora, M.,, Nathanson, K.L., Easton, Douglas F, Thilo Dork, Zamora, M.P., Hans J P Gille, Hsiung, C.-N. (Chia-Ni), Chenevix-Trench, G, GENICA Network, Diether Lambrechts, Baglietto, Laura,, Yu, Jyh Cherng, Anthony Renwick (146533), Ko, YD, Celine Vachon (89914), Roger L Milne, Humphreys, Manjeet K.,, Peter Devilee, Shen, C-Y. (Chen-Yang), McGuffog, Lesley,, Giles, G.G. (Graham), Domchek, Susan M., Baglietto, Laura, J. Hooning, Maartje,, Offit, K., Couch, FJ, Sara Margolin (146586), Evans, D.G., Lorna Gibson (153960), Laura J. Van ‘t Veer (153941), Ong, Kai-Ren,, Hammet, Fleur, Eeles, R, Nevanlinna, Heli, Cook, Jackie, Reed, M.W., Healey, S., Ligtenberg, MJ, Hodgson, S., Devilee, Peter, Benítez, J, Yu, J.C., Wu, P.E., Renwick, Anthony, Verheus, M. (Martijn), Rahman, Nazneen, Kang, D. (Daehee), Fergus J. Couch (146607), Schmidt, Marjanka K, Tollenaar, Robert AEM, Graham G Giles, Beesley, J, Schürmann, P, L. Nathanson, Katherine, Antonis C. Antoniou (146788), Juul T. Wijnen (154144), J. P. Gille, Hans,, K. Schmidt, Marjanka,, Olivia Fletcher (146442), Nevanlinna, Heli,, Beatrice Melin (113531), Bermisheva, M, Tuomas Heikkinen, Couch, Fergus J., Kosma, Veli-Matti,, Schmidt, M.K., Benítez, Javier, Wachenfeldt, A. von, Pei-Ei Wu, Beatrice Melin, Burwinkel, B. (Barbara), Barbara Burwinkel, Pesch, Beate, Holland, Helene, Vachon, C. (Celine), Martijn Verheus (154103), Douglas, Fiona, Couch, F.J., Arias Pérez, J.I. (José Ignacio), Alison M Dunning, Angela Cox, Hodgson, S.V. (Shirley), Dunning, Alison M., Sei-Hyun Ahn (153880), Mannermaa, A., Thijs Van Dorpe (153995), Hiltrud Brauch, Chen, X, Hamann, U., Chang-Claude, J., Peto, J. (Julian), Baglietto, L., Ahn, S.-H., Douglas F Easton, Manjeet K. Humphreys (146790), Fischer, H.-P., Wang, X., Ausems, Margreet G E M, Chenevix-Trench, Georgia,, Karstens, J.H. (Johann), Lambrechts, D. (Diether), Pichert, Gabriella,, Irene L Andrulis, Kai-Ren Ong (154173), Malcolm W.R. Reed (153922), Peter Hillemanns (89884), Bojesen, Stig E.,, Wijnen, Juul T, Holland, H, Chia-Ni Hsiung (153981), Khusnutdinova, E.K. (Elza), Verheus, M., Devilee, P. (Peter), Laura Baglietto (89917), Noh, Dong-Young, Brauch, H. (Hiltrud), Hans J.P. Gille (154139), Hoogerbrugge, N., Spurdle, A.B., Brock, I., Seal, S. (Sheila), Olson, J.E. (Janet), Caligo, Maria A., Jonathan Beesley (89897), Kang, Daehee,, Fischer, Hans Peter, Arto Mannermaa (89891), Arias, J.I., Veer, L.J. (Laura) van 't, Karstens, Johann H, Cook, Jackie,, Oldenburg, R.A. (Rogier), AOCS Study Group (154052), Lindor, N., M. Aalfs, Cora, Cora M. Aalfs (154133), Cook, J. (Jackie), Henrik Flyger, Kauppinen, J., L. Milne, Roger,, Oliver, Clare T., Agnarsson, B.A., Khusnutdinova, Elza, J. Ligtenberg, Marjolijn,, Seal, S., Fiona Douglas, Yon-Dschun Ko, Tollenaar, Robert A.E.M., Offit, K. (Kenneth), Harth, Volker, Javier Benitez (81758), Amanda B. Spurdle (47489), L. Andrulis, Irene,, Rosemarie Davidson (154164), Andrulis, Irene L., Fiona Douglas (154179), Chang-Claude, Jenny,, I. Rogov, Juri, Eccles, Diana, Stenmark Askmalm, M, F. Easton, Douglas, Oldenburg, Rogier A., Clare T. Oliver (154158), Davidson, Rosemarie, Prokofieva, D. (Daria), José Ignacio Arias (154038), Ahn, SH, Seynaeve, Caroline,, Yoo, K-Y. (Keun-Young), Renwick, A, Dunning, AM, Chen, X. (Xiaoqing), B. L. Hogervorst, Frans, Easton, DF, Noralane Lindor (154074), Kang, D, Elliott, G. (Graeme), Bogdanova, N.V. (Natalia), Graeme Elliott (153916), Hogervorst, F.B.L., Meindl, A. (Alfons), Annika Lindblom (26099), Bojesen, S.E. (Stig), Susan Peock, Eeles, Rosalind, Hopper, J.L. (John), Dunning, Alison M.,, Yu, Jyh-Cherng, Brüning, Thomas, Ko, Y.-D., Mia M Gaudet, Tobias, E.S., Juri I. Rogov (154016), Askmalm, M.S. (Marie), Stenmark Askmalm, Marie,, Chenevix-Trench, Georgia, Olson, J., Shen, Chen-Yang, Vachon, C.M., Justenhoven, Christina, Southey, M.C., Laura J Van 't Veer, Wijnen, Juul T., Aalfs, Cora M, Seal, S, Nathanson, KL, Godwin, A.K., Heikkinen, T, Vachon, Celine, Sara Margolin, kConFab, Ute Hamann, Fleur Hammet, Rogov, J.I., Lindor, Noralane, Marjanka K Schmidt, T. Oliver, Clare,, Noralane Lindor, Antoniou, Antonis C., Kai-Ren Ong, Reed, MWR, M Pilar Zamora, Andrulis, I.L., Wang-Gohrke, Shan,, Caligo, M.A., Karlsson, P, D Gareth Evans, Reed, Malcolm W R, Kosma, V-M. (Veli-Matti), Shen, Chen Yang, Margreet G.E.M. Ausems (154127), J. Hooning, Maartje, Brauch, Hiltrud, Verheus, Martijn,, Broeks, Annegien,, Elliott, G., Peto, Julian,, Wu, P.-E., Lambrechts, D, Wang-Gohrke, S. (Shan), Antonenkova, Natalia, Rogov, Juri I., Healey, Sue, J. Van t Veer, Laura,, Hammet, Fleur,, Agnarsson, BA, Chu, C, Yoo, KY, Chen, X.Q., Rookus, Matti A., Dieudonne, A-S., Wu, Pei-Ei,, Sheila Seal, Beesley, J., Cook, M, Nordestgaard, B.G. (Børge), Yoo, Keun-Young,, Clare Turnbull (146523), Karlsson, P. (Per), Maartje J Hooning, Ignacio Arias, Jose,, von Wachenfeldt, Anna,, Loman, N, Healey, Sue,, Cook, J, Bogdanova, N., Hiltrud Brauch (89877), Rahman, Nazneen,, Ahn, S-H., Van 't Veer, Laura J, Pichert, G. (Gabriella), Arias, José Ignacio, Chenevix-Trench, G. (Georgia), von Wachenfeldt, A, Gibson, L, Bjarni A. Agnarsson (154067), Melin, B., Hopper, John L, Jyh-Cherng Yu (146771), Lindblom, A, Eeles, R. (Rosalind), Pichert, Gabriella, Prokunina-Olsson, Ludmila, Askmalm, MS, Lindor, N.M. (Noralane) +999 morecore +5 more sourcesChronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...Anu Singh, Aroonima Misra, Sufian Zaheerwiley +1 more source
