Results 151 to 160 of about 73,095 (214)

Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska, Radoslav Stojchevski, Aleksandar Eftimov, Mitko Mladenov, Dimiter Avtanski, Nikola Hadzi‐Petrushev   +5 more
wiley   +1 more source

Identification and Computational Analysis of <i>BRCA1</i> Variants in Mexican Women from Jalisco, Mexico, with Breast and Ovarian Cancer. [PDF]

Med Sci (Basel)
Gallegos-Arreola MP, Garibaldi-Ríos AF, Dávalos-Rodríguez IP, Magaña-Torres MT, Figuera LE, Zúñiga-González GM, Gómez-Meda BC, Torres-Mendoza BM, Villegas-Pacheco R, Gómez-Cerda R, Cárdenas-Valdez JC, Meza-Chavolla SO, Rosales-Reynoso MA, Ángeles-Bueno WG, Gómez-Villegas MJ, Espinoza DDRP, García-Ortiz JE.   +16 more
europepmc   +1 more source

Clinical Benefit of Pembrolizumab in Lynch Syndrome‐Associated Advanced Ovarian Cancer With Germline MSH6 Variant: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT This case highlights the importance of genetic evaluation during treatment in young patients with advanced ovarian cancer. Lynch syndrome caused by a germline MSH6 pathogenic variant was diagnosed during first‐line maintenance therapy, and pembrolizumab achieved a durable response in recurrent disease.
Tomomi Yokozawa, Sayako Nakagawa, Yukio Suzuki, Aya Tokinaga‐Uchiyama, Katsuyuki Konnai, Hiroto Narimatsu, Yukihiko Hiroshima, Haruya Saji   +7 more
wiley   +1 more source

Procyanidin C1 combined with olaparib induces senescence in BRCA1-proficient breast cancer cells. [PDF]

Am J Cancer Res
Ren C, Fu C, Chen X, Yang R, He J, Gao A, Su Q, Teng X, Xu J.   +8 more
europepmc   +1 more source

An In Vitro and In Vivo Assessment of the Anti‐Breast Cancer Activity of Erythrina excelsa Baker (Fabaceae) Bark Extracts

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Breast cancer remains a topic of interest due to its high mortality rate among Cameroonian women. The barks of Erythrina excelsa are traditionally used for medicinal purposes in the management of various conditions including cancer.
Jonas Walantini, Marius Trésor Kemegne Sipping, Merline Nguedia Ymele, Roland Nhouma Rebe, Joël Abel Gbaweng Yaya, Derek Tantoh Ndinteh, Dieudonné Njamen, Stéphane Zingue   +7 more
wiley   +1 more source

TFAP2A enhances radioresistance of non-small cell lung cancer by transcriptionally activating BRCA1 : TFAP2A promotes NSCLC radioresistance. [PDF]

Cell Oncol (Dordr)
Ma J, Wang F, Zhang J, Tian C, Bao S, Yuan J, Yu J, Zhang X, Chen D.   +8 more
europepmc   +1 more source

Germline BRCA2 Pathogenic Variant in Metaplastic Breast Carcinoma with Heterologous Mesenchymal Differentiation: A Case Report and Literature Review. [PDF]

Reports (MDPI)
Arduini A, Polati R, Bonisoli GL, Sina S.   +3 more
europepmc   +1 more source

Age‐Associated Four‐Gene Prognostic Signature in Breast Cancer

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Young‐onset breast cancer is associated with inferior disease‐free survival (DFS), but the contribution of additional molecular heterogeneity remains unclear. Aims To identify an exploratory age‐associated gene expression signature linked to recurrence‐related outcomes and evaluate its prognostic association.
Shiro Uchida
wiley   +1 more source

Liquid biopsy: a new window on the BRCA genes. [PDF]

ESMO Open
Incorvaia L, Gristina V, Pepe F, Bazan Russo TD, Santoni M, Mujacic C, Curigliano G, Malapelle U, Capoluongo ED, Russo A.   +9 more
europepmc   +1 more source

Choline metabolism drives metastasis in BRCA1-deficient ovarian cancers by activating FAM3C. [PDF]

Nat Commun
Wang C, Xie X, Li J, Zhu J, Sun B, Wu Y, Zhang W, Li D, Chen G.   +8 more
europepmc   +1 more source