Results 191 to 200 of about 74,972 (273)

Selective Autophagy Receptor CsNBR1 Confers Citrus Huanglongbing Resistance by Degrading ‘Candidatus Liberibacter Asiaticus’ Virulence Effectors

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
Overexpression of CsNBR1 confers HLB resistance in citrus by degrading CLas effector proteins, including SDE5115, SDE1, SDE19 and SDE5, via the autophagy pathway. ABSTRACT The selective autophagy receptor NEIGHBOUR OF BRCA1 (NBR1) is a key regulator of plant immunity, but its role against bacterial pathogens remains poorly understood.
Yaqian Shi, Xuejin Cui, Fang Fang, Zaiyu Yang, Yalin Mei, Shimian Ma, Changyong Zhou, Xuefeng Wang   +7 more
wiley   +1 more source

Gastric Epithelium from BRCA1 and BRCA2 Carriers Harbors Increased Double-Stranded DNA Damage and Enhanced Growth Potential. [PDF]

Mol Cancer Res
Buckley KH, Dungan ME, Dinh K, Kelly GM, Hausler R, Bennett KE, Clay DG, Youngman JE, Majer AD, Beyries KA, Niccum BA, Shaffer SM, Karakasheva TA, Hamilton KE, Kochman ML, Ginsberg GG, Ahmad N, Maxwell KN, Katona BW.   +18 more
europepmc   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

Interactions of the Nijmegen Breakage Syndrome Protein with ATM and BRCA1

Cold Spring Harbor Symposia on Quantitative Biology, 2000
X, Wu, G, Rathbun, W S, Lane, D T, Weaver, D M, Livingston   +4 more
openaire   +2 more sources

The Performance of <i>In Silico</i> Prediction Tools for Variant Curation in a Panel of Cancer Genes. [PDF]

Hum Mutat
Nelson N, Niaz A, Fairfax K, Bryan TM, Lucas S, Dickinson J.   +5 more
europepmc   +1 more source

BRCA1-associated protein 1 (BAP1) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

A report of novel inactivating missense mutations of BRCA1 detected in patients with acute myeloid leukemia. [PDF]

J Med Case Rep
Ejaz S, Raashid A, Hameed Y, Abdullah I, Imtiaz N, Iqbal M, Khurshid M, Malik WN.   +7 more
europepmc   +1 more source

Molecular architecture of the tumor microenvironment caused by <i>BRCA1</i> and <i>BRCA2</i> somatic mutations in human lung adenocarcinoma. [PDF]

Elife
Liao G, Yang X, Liu Q, Nan S, Liu Y, Li J, Huang S, Ning W, Qin X, Xu G.   +9 more
europepmc   +1 more source

Real-World Outcomes of CDK4/6 Inhibitors in Germline BRCA1/2-Mutated Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Turkish Oncology Group (TOG) Study. [PDF]

Curr Oncol
Seyyar M, Kalem A, Sali M, Karabuğa B, Sahin TK, Dişli AK, Türkel A, Karadurmuş B, Şahin Hafızoğlu E, Avcı N, Bilgetekin I, Köse Baytemur N, Uguztemur E, Oflazoğlu U, Gür HB, Hacıbekiroğlu İ, Akkuş AF, Topaloğlu S, Bayramgil A, Dülgar Kaya Ö, Yazıcı M, Şakalar T, Akay S, Majidova N, Guliyev M, Alan Ö, Gülcü S, Eren T, İmamoğlu Gİ, Güren AK, Köstek O, Ünlü A, Ozturk B, Aydın E, Safarov S, Doğan B, Tükenmez MA, Demir T, Şahin E, Erdemoğlu E, Keskin Uzundere F, Bütün O, Karabulut B, Uzun M, Baydaş T, Karaman E, Arak H, Ekinci F, Aykan MB, Ertürk İ, Guven DC, Deligönül A, Karaçin C, Ateş Ö, İnanç M, Yeşil H, Aksoy S, Köşeci T, Ökten İN, Yıldırım HÇ, Çabuk D.   +60 more
europepmc   +1 more source

Higher Levels of <i>BRCA1</i> Gene Methylation in Sporadic Breast Cancer Patients with a Lower Incidence of Recurrence. [PDF]

Med Sci (Basel)
Agnes G, Damin APS, Watte G, Guimarães GR, Roehe AV, Saffi J.   +5 more
europepmc   +1 more source