Results 221 to 230 of about 111,862 (289)

Endogenous and environmental factors that induce DNA replication defects and genomic instability in ER-negative heterozygous BRCA1 cells. [PDF]

Sci Rep
Deshpande M, Paniza T, Brown R, Heslin K, Patel N, Madireddy A, Rosenwaks Z, Gerhardt J.   +7 more
europepmc   +1 more source

Case report: a rare BRCA1 de novo variant in a female with breast cancer. [PDF]

Hered Cancer Clin Pract
Dencker C, Strehlow V, Aktas B, Lemke J, Hentschel J.   +4 more
europepmc   +1 more source

MMTV Virus Detection, Survival Analysis, and Prognostic Relevance of Six Tumor Genes in Patients With Breast Cancer. [PDF]

Int J Breast Cancer
Alamri S, Awadalla M, Henawi RA, Al-Hazzaa G, Alkhunaizy Z, Alzorgi S, Alqahtani N, Abdel Halim AS, Ali MAM, Almansour MI, Alosaimi B.   +10 more
europepmc   +1 more source

Repression of EGFR by new biguanide 4C potentiated ovarian cancer to PARP inhibitors through down-regulation of BRCA2 and Rad51. [PDF]

Cell Death Dis
Xiao D, Yao J, Yang X, Xie Y, Zhou X, Li D, Peng M, Wang W, Zou H, Yang X.   +9 more
europepmc   +1 more source

A novel BRCA mutation classification system reveals differential responses to PARP inhibition and prognostic outcomes in epithelial ovarian cancer: a multicenter study. [PDF]

ESMO Open
Liu Q, Fan Y, Huang C, Wu M, Jin Y, Tao L, Liu Y, Song J, Wang S, Kong W, Huang X, Ha C, Cui Z, Zhao D, Yang X, Qiao J, Zhang Y, Li Y, Guo H.   +18 more
europepmc   +1 more source

Functional assessment of protein variants in structured domains by fluorescence cross-correlation spectroscopy. [PDF]

Sci Rep
Mateu-Regué À, Mariani L, Bagger FO, Bose M, Nielsen FC.   +4 more
europepmc   +1 more source

Disease- and gene-specific deep learning for pathogenicity prediction of rare missense variants in cancer predisposition genes. [PDF]

BioData Min
Lee DB, Kang HU, Hwang KB.
europepmc   +1 more source

Surgical Outcomes After Risk-Reducing Mastectomy Among BRCA1 and BRCA2 Carriers.

JAMA Netw Open
Wiberg R, Hägglund S, Numan Hellquist B, Rosén A, Idahl A, Mani M, Bajalica-Lagercrantz S, Ehrencrona H, Karlsson P, Loman N, Sund M, Swedish BRCA Study Group.   +11 more
europepmc   +1 more source

Advancing inducible gene-inactivation systems to explore synthetic lethality. [PDF]

NAR Cancer
Sánta ÁT, Gráf A, Vincze-Kontár K, Kovács K, Bóna B, Mórocz M, Kiss E, Haracska L.   +7 more
europepmc   +1 more source

The Effects of <i>BRCA1</i> and <i>BRCA2</i> Promoter Methylation on Clinicopathological Characteristics and Clinical Outcomes in HGSOC. [PDF]

Cells
Živić K, Boljević I, Nedeljković M, Matović M, Janković R, Tanić M.   +5 more
europepmc   +1 more source