Results 181 to 190 of about 68,288 (264)

BRCA2 in abscission [PDF]

Nature Cell Biology, 2012
openaire   +1 more source

Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs

Cancer Science, Volume 117, Issue 3, Page 587-596, March 2026.
Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi, Rubaiat E. Tabassum, Kouji Hirota   +2 more
wiley   +1 more source

Frequency of Founder Mutations in <i>BRCA1</i> and <i>BRCA2</i> Genes in Hereditary Breast Cancers in Poland vs. Other Countries. [PDF]

Cancers (Basel)
Kulikowska B, Panasiuk B, Posmyk R.
europepmc   +1 more source

Identification of BCL2L11 as a Candidate Gene for Hereditary Predisposition to Non‐Medullary Thyroid Cancer Using Familial Whole‐Exome‐Sequencing

Clinical Genetics, Volume 109, Issue 3, Page 458-469, March 2026.
Whole‐exome sequencing of five families with non‐medullary thyroid cancer revealed three candidate genes. Functional analyses confirmed BCL2L11 as a strong candidate gene for hereditary predisposition to non‐medullary thyroid cancer. ABSTRACT Familial non‐medullary thyroid cancer, defined as two or more affected first‐degree relatives, accounts for 3 ...
Duygu Abbasoglu, Mathis Lepage, Nicolas Sonnier, Sandrine Viala, Nancy Uhrhammer, Flora Ponelle‐Chachuat, Anne Cayre, Maud Privat, Mathias Cavaillé, Yannick Bidet   +9 more
wiley   +1 more source

Invasive Lobular Carcinoma of the Male Breast With BRCA2 Mutation. [PDF]

Case Rep Pathol
Abe M, Saito F, Honma N, Tamaki Y, Goto M, Fukutake K, Sonobe S, Katagiri Y, Shibayama T, Ogata H.   +9 more
europepmc   +1 more source

BRCA1 and BRCA2: different roles in a common pathway of genome protection

Nature Reviews. Cancer, 2011
Rohini Roy, Jarin Chun, S. Powell
semanticscholar   +1 more source

Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature

Histopathology, Volume 88, Issue 4, Page 831-842, March 2026.
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Costantino Ricci, Dario de Biase, Thais Maloberti, Agnese Orsatti, Thomas M Ulbright, Muhammad T Idrees, Esther Oliva, Kristine Cornejo, João Lobo, Kvetoslava Michalova, Maria Rosaria Raspollini, Sean R Williamson, Geert JLH van Leenders, Chia‐Sui Kao, Fiona Maclean, Ankur R Sangoi, Adeboye O Osunkoya, Michelangelo Fiorentino, Antonio De Leo, Giovanni Tallini, Andres Martin Acosta   +20 more
wiley   +1 more source

Updated analysis of pathogenic variants in BRCA1/BRCA2 among the general Japanese population. [PDF]

Hum Genome Var
Mariya T, Idogawa M, Saito T, Nakase H, Tokino T, Sakurai A.   +5 more
europepmc   +1 more source

Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers

Journal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 895-913, March 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of new cancer cases, it is projected to become the second leading cause of cancer‐related deaths by 2030.
Muhammad Masroor Hussain, Sana Qammar, Ju‐Mei Wang, Ao‐Qiang Zhai, Fu‐yu Li, Hai‐jie Hu   +5 more
wiley   +1 more source

BRCA2 Biallelic Inactivation [PDF]

, 2020
openaire   +1 more source