Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.LINC01537 is upregulated in breast cancer, predicting poor prognosis; it acts as a ceRNA sponging miR‐138‐5p to upregulate EZH2, promoting breast cancer progression via this axis. ABSTRACT Breast cancer is a highly heterogeneous malignancy and constitutes one of the leading health threats to women globally.
Yuetong Guo, Libo Shi
wiley +1 more source
The impact of BRCA mutation and hormone receptor status on the outcomes of fertility preservation in breast cancer patients: a systematic review and meta-analysis. [PDF]
Front OncolYe L, Yang W, Guan H.
europepmc +1 more source
Pan‐Cancer Landscape of TMEM9 With Experimental Validation in Head and Neck Squamous Cell Carcinoma
The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.Transmembrane protein 9 (TMEM9) was investigated across cancers using public transcriptomic, clinical, genomic, and immune datasets, followed by functional validation in head and neck squamous cell carcinoma (HNSC). TMEM9 showed cancer‐dependent expression, diagnostic discrimination, prognostic associations, and relationships with immune infiltration ...
Mi Wang +3 more
wiley +1 more source
Real-World Epidemiology, Clinical Characteristics and Outcomes of Women with Germline BRCA Mutation and Early Breast Cancer in China. [PDF]
Oncol TherHu Z +11 more
europepmc +1 more source
MedComm, Volume 7, Issue 11, November 2026.PRAME promotes lung adenocarcinoma metastasis by inducing K63‐linked ubiquitination of METTL3 at lysine 235, thereby enhancing METTL3 stability and m6A methyltransferase complex assembly. Elevated METTL3 activity increases m6A modification of TGFB2 mRNA, leading to activation of TGF‐β signaling and metastatic progression of lung adenocarcinoma (LUAD ...
Xia Yang +21 more
wiley +1 more source
BRCA mutation and multiple primary malignancies: a rare case of recurring triple-negative breast cancer and cervical cancer. [PDF]
EcancermedicalscienceNaciri M +6 more
europepmc +1 more source
Cancer Science, Volume 117, Issue 11, Page 3160-3170, November 2026.AI‐based spatial analysis of tumor‐infiltrating lymphocytes in ovarian cancer revealed the highest infiltration in high‐grade serous carcinoma. Integrating pathology‐based immune phenotypes with HRD status provided additional prognostic insight and highlighted distinct relationships between TILs and genomic structure.
Kohei Hamada +17 more
wiley +1 more source
A Phase II Pilot Study of Anti-PD-L1, Durvalumab, and a PARP Inhibitor, Olaparib in Patients With Metastatic Triple-Negative Breast Cancer With or Without Germline BRCA Mutation. [PDF]
Cancer MedFujii T +13 more
europepmc +1 more source
Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy
Cancer Science, Volume 117, Issue 11, Page 2910-2923, November 2026.This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang +6 more
wiley +1 more source