Results 131 to 140 of about 35,907 (256)
, 2016 (A) Correlation between overall mutation rate and number of predicted neoantigens in TNBC. (B) Expression of immune metagenes as a function of the estimated clonality of tumors. Clonal tumors are associated with a significantly enhanced immune presence. (
Vikram B. Wali (3396224) +10 more
core +1 more source
Women's experiences of living with BRCA-mutation : A general literature review
, 2020 Bakgrund: BRCA-mutation är en ärftlig mutation som ökar risken för bröst- och ovarialcancer hos kvinnor. Kvinnor med BRCA-mutation får genomgå ökad bevakning hos sjukvården samt ställs inför profylaktiska val.
Permin, Felicia, Sunesson, Sandra
core +1 more source
DiseasesBackground: Breast cancer is the most frequently diagnosed cancer in women, and advances in genetic screening have led to a growing number of patients being identified as BRCA mutation carriers.
Cristina Tanase-Damian +9 more
doaj +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.Sex‐stratified analyses of the TCGA and CGGA cohorts have identified promoter‐proximal TACSTD2 CpG sites where methylation shows opposite survival associations in males and females, is independent of copy number, and correlates with TACSTD2 expression.
Tahreem Fatima
wiley +1 more source
, 2002 Previous mutational analysis for BRCA gene mutations in sporadic ovarian cancer occurring in Chinese patients in Hong Kong identified six germline BRCA1 mutations and one germline BRCA2 mutation, six of which were novel (Khoo et al., 2000).
Choy, KW +11 more
core
BRCA mutation screening and patterns among high-risk Lebanese subjects
, 2019 Background Previous studies have suggested that the prevalence of BRCA1 and 2 mutations in the Lebanese population is low despite the observation that the median age of breast cancer diagnosis is significantly lower than European and North American ...
Johnny Awwad +10 more
core +1 more source
Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang +4 more
wiley +1 more source
Choice of management of southern Chinese BRCA mutation carriers
, 2010 Background: Mutations in the BRCA genes confer greater risk of developing breast, ovarian, and prostate cancer. Families carrying the mutation can have intensive surveillance and take preventative measures.
Choi, CLY +4 more
core +1 more source
Biomedical Chromatography, Volume 40, Issue 8, August 2026.ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris +2 more
wiley +1 more source
Expert consensus on population-based
Zhongguo aizheng zazhiGermline mutations in BRCA genes (including BRCA1/2) are the major risk factors for hereditary tumors including breast and ovarian cancer. Population based BRCA gene screening, particularly in high-risk individuals with a family history of cancer, can ...
Anti-Cancer Association Tumor Biomarker Professional Committee China +1 more
doaj