Brca mutation - Open Access .click

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Fertility preservation in BRCA mutation carriers.

Minerva ginecologica, 2016
According to enhanced long-term survival rates of these patients, interest in fertility preservation for young women facing gonadotoxic therapies is increasing. Women who carry a mutation in the BRCA1 or BRCA2 gene have a specifically increased lifetime risk of developing breast and tubo-ovarian cancer.
REVELLI, Alberto +9 more
openaire +3 more sources

Targeting BRCA-mutated tumors in mitosis

Nature Cancer, 2021
Demis Menolfi, Shan Zha
openaire +2 more sources

Variability in Cancer Risk with BRCA Mutations

Cancer Discovery, 2015
Abstract A large systematic analysis of BRCA1 and BRCA2 mutations in women shows that mutation location and type is associated with significant variation in the risk for breast and ovarian cancers.
openaire +2 more sources

Breast-cancer risk in BRCA-mutation-negative women from BRCA-mutation-positive families