Results 131 to 140 of about 3,728 (186)

Punicalagin with anti-inflammatory activities affects Brd-4 mediated chromatin remodeling for attenuating inflammatory osteolysis. [PDF]

Sci Rep
Li H, Li Q, Wan T, Wang Y, Zhang S.
europepmc   +1 more source

Harnessing FBXO31 with Terminal Amide-Functionalized Molecules for Targeted Protein Degradation. [PDF]

J Am Chem Soc
Zhang C, Jin X, Zhou C, Jenkins MJ, Riha IA, Zhang X.   +5 more
europepmc   +1 more source

Correction of the molecular phenotype of X-linked Dystonia-Parkinsonism reveals a non-canonical function of BRD4. [PDF]

Nat Commun
Capponi S, Ehret S, Camgöz Z, Gather F, Vaine CA, Özyerli-Göknar E, Follo M, Bragg DC, Vogel T, Timmers HTM.   +9 more
europepmc   +1 more source

Bromodomain and Extra-Terminal Family Proteins BRD2, BRD3, and BRD4 Contribute to H19-Dependent Transcriptional Regulation of Cell Adhesion Molecules, Modulating Metastatic Dissemination Program in Prostate Cancer. [PDF]

Noncoding RNA
Pecci V, Borsa M, Aiello A, De Martino S, Cis L, Ripoli C, Rotili D, Pierconti F, Pinto F, Grassi C, Gaetano C, Farsetti A, Nanni S.   +12 more
europepmc   +1 more source

Modulation of Bromo- and Extra-Terminal Domain (BET) Proteins Exerts Neuroprotective Effects in Cell Culture Models of Parkinson's Disease. [PDF]

Biomedicines
Martella N, Pensabene D, Colardo M, Muzzi M, Bisesto E, Varone M, Caretti G, Di Porzio A, Barrella V, Mazzoli A, Di Bartolomeo S, Moreno S, Segatto M.   +12 more
europepmc   +1 more source

Human opsin restoration by histone methylation using methyltransferase fusion protein SETD7-dCas9. [PDF]

Mol Ther Nucleic Acids
Tran NL, Kang YE, Jeong H, Kim Y, Shin SC, Kim SH, Park B, Oh SJ.   +7 more
europepmc   +1 more source

Immune biomarker landscape and fusion partner-phenotype associations in thoracic and head-and-neck NUT carcinoma. [PDF]

Front Immunol
Xiang S, Ye Z, Dai Y, Shang S, Yang D, Cheng T, Deng C, Zhang M, Yin M.   +8 more
europepmc   +1 more source

Peptide molecular glues select between BET paralogues by exploiting allosteric sites and conformational dynamics

Patel K, Mohanty B, Norman A, Franck C, Pachl P, Yang L, Jing X, Reid XJ, Walshe JL, Solomon P, Tran DH, Ford D, Low JKK, Wilkinson-White L, Passioura T, Payne RJ, Suga H, Walport LJ, Mackay JP.   +18 more
europepmc   +1 more source

Advantages of PROTACs in achieving selective degradation of homologous protein families. [PDF]

Beilstein J Org Chem
Yang L, Mao X, Zhang J, Shu J, Huang W, Dong X, Chen Y, Wu M.   +7 more
europepmc   +1 more source