Results 151 to 160 of about 3,728 (186)

Pediatric NUT carcinoma: a patient series and literature review. [PDF]

BMC Pediatr
You Y, Lu S, Sun F, He X, Wang J, Huang J, Que Y, Zhen Z, Zhang Y, Zhu J.   +9 more
europepmc   +1 more source

The oncolytic vesicular stomatitis virus VSV-GP shows profound oncolytic activity in NUT-carcinoma cell lines. [PDF]

Mol Ther Oncol
Buchenau RC, Schiller AM, Beil J, Berchtold S, Schenk A, Smirnow I, Carter ME, Schaller M, Fehrenbacher B, Vollert A, Schoeps B, Kleemann R, Lauer UM, Kloker LD.   +13 more
europepmc   +1 more source

Beyond Classical Force Fields: Physics-Driven Assessment of the Grappa Machine-Learned Force Field on the FoldBind Dataset. [PDF]

Chemphyschem
Ranaweera I, Perez A.
europepmc   +1 more source

Molecular Characterization of NUT Carcinoma: A Report from the NUT Carcinoma Registry. [PDF]

Clin Cancer Res
Kim JJ, Walton SA, Mahadevan NR, Haradon J, Paoloni F, Paik PK, Chaft JE, Hsu R, Piha-Paul SA, Jänne PA, Barbie DA, Sholl LM, DuBois SG, Hanna GJ, Shapiro GI, French CA, Luo J.   +16 more
europepmc   +1 more source

Effectiveness of PROTAC BET Degraders in Combating Cisplatin Resistance in Head and Neck Cancer Cells. [PDF]

Int J Mol Sci
Luffman N, Ahmadinejad F, Finnegan RM, Raymond M, Gewirtz DA, Harada H.   +5 more
europepmc   +1 more source

Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. [PDF]

J Biol Chem
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC.   +6 more
europepmc   +1 more source

A novel carboxamide bromodomain inhibitor attenuates osteoarthritis via epigenetic repression of NF-κB and MAPK signaling. [PDF]

Front Immunol
Lee H, Han SJ, Ok S, Lee KM, Choi S, Yoon I, Choi S, Kim J, Ryu S, Son MH, Lee IH, Cho C, Yang S.   +12 more
europepmc   +1 more source

Abstract 1527: BRD3 as a specific vulnerable therapeutic target in neuroblastoma

Cancer Research, 2017
Abstract Introduction: BET inhibitors have raised high expectations for cancer treatment given their anti-proliferative effect by inhibiting BRD4 controlled enhancer activity of highly transcribed genes such as MYC(N). However, current inhibitors also target BRD2 and BRD3 which are functionally nonredundant with BRD4.
Kaat Durinck, Jolien Dewyn, Anneleen Beckers, Siebe Loontiens, Suzanne Vanhauwaert, Daniel Carter, Belamy Chueng, Glenn Marshall, Katleen Depreter, Frank Westermann, Frank Speleman   +10 more
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Establishment of environment-sensitive probes targeting BRD3/BRD4 for imaging and therapy of tumor

European Journal of Medicinal Chemistry, 2023
The BET (bromo and extra-terminal) family proteins are epigenetic readers and master transcription coactivators, which have attracted great interests as cancer therapeutic targets. However, there are few developed labeling toolkits that can be applied for the dynamic studies of BET family proteins in living cells and tissue slices.
Tingting Liu
exaly   +3 more sources