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Insights into Monkeypox Virus: Host Immunity, Viral Immune Evasion, Recent Advances in Vaccines, Therapeutic Development, and Future Perspectives. [PDF]
Chen M +7 more
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Monkeypox (Mpox), a Resurging Global Public Health Concern: An Updated Outlook Through 2025. [PDF]
Islam DZ +13 more
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The Emerging Threat of Monkeypox: An Updated Overview. [PDF]
Yahya G +8 more
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Brincidofovir: A Novel Agent for the Treatment of Smallpox
Annals of Pharmacotherapy, 2023Objective: This article reviews the published data encompassing the development, pharmacology, efficacy, and safety of brincidofovir, a nucleotide analogue DNA polymerase inhibitor developed for the treatment of smallpox. Data Sources:
Jessica Huston +2 more
openaire +4 more sources
The use of brincidofovir for the treatment of mixed dsDNA viral infection
Journal of Clinical Virology, 2016Double-stranded DNA (dsDNA) viral infections constitute a major complication following solid organ and stem cell transplantation. Few therapeutic options are currently available for the treatment of such infections in highly immunocompromised hosts. Brincidofovir is an oral investigational drug with broad antiviral activity against dsDNA viruses in ...
Jose F, Camargo +7 more
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Brincidofovir as Salvage Therapy for Adenovirus Disease in Intestinal Transplant Recipients
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2018BackgroundAdenoviruses are double‐stranded DNA viruses that typically cause mild self‐limiting respiratory, ocular, and gastrointestinal infections. In immunocompromised patients, especially transplant recipients, the infection can be severe, with dissemination and multiorgan failure. In intestinal transplant recipients, the incidence is as high as 57%.
Nimisha Sulejmani +6 more
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