Results 81 to 90 of about 2,652 (202)

Entre epidemias e pandemias: as diferentes dimensões da crise do Ébola 2013/2016 [PDF]

open access: yes, 2016
a crise do Ébola 2013/2016 foi especialmente alarmante para o mundo. O que é que esta epidemia trouxe de novo? Além de maior número de casos, desta vez observou-se: a intensificação dos esforços institucionais coordenados para evitar a expansão ...
Marques, Teresa Sá   +1 more
core  

Engineered Nile Red Derivatives‐Mediated Efficient Phototherapy Against Drug‐Resistant Bacteria and Monkeypox Virus

open access: yesAggregate, Volume 6, Issue 10, October 2025.
TPAOMCN exhibits optimal reactive oxygen species (ROS) generation and photothermal conversion properties. TPAOMCN nanofibers (NFs)‐mediated photodynamic (PDT) and photothermal therapy (PTT) achieved efficient eradication against multidrug‐resistant bacteria and viruses, alleviating inflammation response, promoting wound healing, and providing a ...
Laiping Fang   +9 more
wiley   +1 more source

Current Progress in Targeting Human Cytomegalovirus Infection

open access: yesiLABMED, Volume 3, Issue 3, Page 303-311, September 2025.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Smallpox in the Post-Eradication Era [PDF]

open access: yes, 2020
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Ehmann, Meyer, Smith
core   +1 more source

The Role of Public Health Interventions and Control Measures During Mpox Outbreaks: Enhancing Strategies for Disease Prevention and Management

open access: yesPublic Health Challenges, Volume 4, Issue 3, September 2025.
This paper highlights key public health interventions and control strategies implemented during mpox outbreaks, emphasizing early detection, targeted prevention, and the role of vaccination and education in mitigating disease transmission. ABSTRACT Mpox (formerly—monkeypox) is the second viral pit break after COVID‐19.
Muhammad Shaheer Bin Faheem   +6 more
wiley   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

open access: yesAdvanced Science, Volume 12, Issue 26, July 10, 2025.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su   +12 more
wiley   +1 more source

Discovery of Broad-Spectrum Antiviral Agents by Drug Repurposing for Rapid Response to Emergent Viral Pandemics: Building Digital Tools to Advance Translational Research [PDF]

open access: yes, 2021
The ongoing COVID-19 pandemic caused by the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in 2019 has highlighted urgency for a more efficient and comprehensive paradigm for antiviral development.
Yao, Rouan
core  

Addressing the Health Risks Posed by Adenovirus: A Perspective on Strategies for Prevention and Management

open access: yesHealth Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background Adenovirus (AdV) is a non‐enveloped virus with a double‐stranded DNA genome that can infect the respiratory and gastrointestinal tracts, as well as cause conjunctivitis. The infection is influenced by the patient's age, environment, temperature, and immunocompromised individuals.
Taslima Jamal Urmi   +2 more
wiley   +1 more source

A REVIEW ON MONKEY POX DISEASE [PDF]

open access: yes, 2022
After the disastrous COVID-19 pandemic, now, monkey pox has spreaded its legs all over the world. Disease originated in Africa but its outbreak occurred in 89 countries since January 2022. As per the World Health Organization report, in between January 1,
GUHA, SOURAV, KAMARIA, PRIYANKA
core   +1 more source

A Multimodal Treatment Strategy to Manage Severe Cutaneous Mpox

open access: yesAnnals of Internal Medicine: Clinical Cases
A 33-year-old bisexual man with advanced HIV and severe mpox developed severe cutaneous disease despite receiving tecovirimat, antiretroviral therapy, and vaccinia immune globulin.
Navin Bhatt   +6 more
doaj   +1 more source

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