Results 81 to 90 of about 2,652 (202)
Entre epidemias e pandemias: as diferentes dimensões da crise do Ébola 2013/2016 [PDF]
a crise do Ébola 2013/2016 foi especialmente alarmante para o mundo. O que é que esta epidemia trouxe de novo? Além de maior número de casos, desta vez observou-se: a intensificação dos esforços institucionais coordenados para evitar a expansão ...
Marques, Teresa Sá +1 more
core
TPAOMCN exhibits optimal reactive oxygen species (ROS) generation and photothermal conversion properties. TPAOMCN nanofibers (NFs)‐mediated photodynamic (PDT) and photothermal therapy (PTT) achieved efficient eradication against multidrug‐resistant bacteria and viruses, alleviating inflammation response, promoting wound healing, and providing a ...
Laiping Fang +9 more
wiley +1 more source
Current Progress in Targeting Human Cytomegalovirus Infection
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley +1 more source
Smallpox in the Post-Eradication Era [PDF]
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Ehmann, Meyer, Smith
core +1 more source
This paper highlights key public health interventions and control strategies implemented during mpox outbreaks, emphasizing early detection, targeted prevention, and the role of vaccination and education in mitigating disease transmission. ABSTRACT Mpox (formerly—monkeypox) is the second viral pit break after COVID‐19.
Muhammad Shaheer Bin Faheem +6 more
wiley +1 more source
Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su +12 more
wiley +1 more source
Discovery of Broad-Spectrum Antiviral Agents by Drug Repurposing for Rapid Response to Emergent Viral Pandemics: Building Digital Tools to Advance Translational Research [PDF]
The ongoing COVID-19 pandemic caused by the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in 2019 has highlighted urgency for a more efficient and comprehensive paradigm for antiviral development.
Yao, Rouan
core
ABSTRACT Background Adenovirus (AdV) is a non‐enveloped virus with a double‐stranded DNA genome that can infect the respiratory and gastrointestinal tracts, as well as cause conjunctivitis. The infection is influenced by the patient's age, environment, temperature, and immunocompromised individuals.
Taslima Jamal Urmi +2 more
wiley +1 more source
A REVIEW ON MONKEY POX DISEASE [PDF]
After the disastrous COVID-19 pandemic, now, monkey pox has spreaded its legs all over the world. Disease originated in Africa but its outbreak occurred in 89 countries since January 2022. As per the World Health Organization report, in between January 1,
GUHA, SOURAV, KAMARIA, PRIYANKA
core +1 more source
A Multimodal Treatment Strategy to Manage Severe Cutaneous Mpox
A 33-year-old bisexual man with advanced HIV and severe mpox developed severe cutaneous disease despite receiving tecovirimat, antiretroviral therapy, and vaccinia immune globulin.
Navin Bhatt +6 more
doaj +1 more source

