Results 61 to 70 of about 1,885 (156)

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics

MedComm, Volume 7, Issue 1, January 2026.
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan, Yaqin Sun, Guangyan Sun, Cheng Niu, Xinyuan Zhao, Ming Zhao, Tongyao Liu, Suyue Zhang, Hui Zhai, Ankang Liu, Shouzhi Yu, Shuyuan Pan, Wu Zhong, Yuntao Zhang, Song Li   +14 more
wiley   +1 more source

Buccal viral DNA as a trigger for brincidofovir therapy in the mousepox model of smallpox [PDF]

Antiviral Research, 2017
Orthopoxviruses continue to pose a significant threat to the population as potential agents of bioterrorism. An intentional release of natural or engineered variola virus (VARV) or monkeypox viruses would cause mortality and morbidity in the target population.
Ryan Crump, Maria Korom, R. Mark Buller, Scott Parker   +3 more
openaire   +2 more sources

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Intestinal and Multivisceral Transplantation: Where We Stand Today

Pediatric Transplantation, Volume 30, Issue 1, January 2026.
ABSTRACT Intestinal and multivisceral transplantation has evolved from an experimental to a life‐saving procedure for children and adults with complications of gut failure (GF). Suboptimal long‐term outcomes of transplant elicit recent advances in surgical and medical gut rehabilitation along with the introduction of glucagon‐like peptide‐2 (GLP‐2 ...
Mohamed Maklad, Mohammed Osman, Mariam Ismail, Tetsuya Tajima, Kadakkal Radhakrishnan, Masato Fujiki   +5 more
wiley   +1 more source

A Case of Cowpox Presenting as Progressive Unilateral Facial Swelling and Fever Without Any Skin Lesions

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Introduction Although a rare infection, sporadic human cases of cowpox do occur in endemic areas, often through contact with an infected cat. Cats are also incidental hosts but provide an important intermediary to the animal reservoir for cowpox, which in the United Kingdom (UK) includes bank and field voles. Case Discussion We present a case of cowpox
Oliver T. R. Toovey, Simon C. Wooding, Amy Belfield, Jenna Furneaux, Nicola Eisenhauer, Tommy Rampling, Priya Gusain   +6 more
wiley   +1 more source

Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer‐Aided Drug Design

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Leilei ZHAO, Jing QU, Miao AN, Yang LIU, Xiubo LI, Yiming LIU, Chen PENG, Todd R. Callaway   +7 more
wiley   +1 more source

Dose-dependent efficacy of intravenous brincidofovir across adenovirus species in immunocompromised patients

Journal of Infection
Summary: Objectives: Invasive infections caused by different human adenovirus (HAdV) species represent a life-threatening complication in immunocompromised patients, but no approved antiviral treatment is currently available.
Chantal Lucini, Nkechie Azie, Sunando Roy, Helena Tutill, Rachel Williams, Judith Breuer, Sandra Preuner, Lisa Grösslinger, Thomas Lion   +8 more
doaj   +1 more source

A Multimodal Treatment Strategy to Manage Severe Cutaneous Mpox

Annals of Internal Medicine: Clinical Cases
A 33-year-old bisexual man with advanced HIV and severe mpox developed severe cutaneous disease despite receiving tecovirimat, antiretroviral therapy, and vaccinia immune globulin.
Navin Bhatt, John Winters, Yusra Shah, Victoria E. Ruiz, Ofole Mgbako, Marcia Wong, Madeline A. DiLorenzo   +6 more
doaj   +1 more source

Brincidofovir Use after Foscarnet Crystal Nephropathy in a Kidney Transplant Recipient with Multiresistant Cytomegalovirus Infection

Case Reports in Transplantation, 2017
Background. Cytomegalovirus (CMV) antiviral drug resistance constitutes an increasing challenge in transplantation. Foscarnet is usually proposed when resistance for ganciclovir is suspected, but its use is limited by its nephrotoxicity.
Romain Vial, Christine Zandotti, Sophie Alain, Alexandre Decourt, Noémie Jourde-Chiche, Raj Purgus, Charleric Bornet, Laurent Daniel, Valérie Moal, Tristan Legris   +9 more
doaj   +1 more source

Mpox: Global epidemic situation and countermeasures

Virulence
Mpox, is a zoonotic disease caused by the monkeypox virus and is primarily endemic to Africa. As countries gradually stop smallpox vaccination, resistance to the smallpox virus is declining, increasing the risk of infection with mpox and other viruses ...
Wenshuang Hou, Nan Wu, Yanzhi Liu, Yanjun Tang, Quan Quan, Yinghua Luo, Chenghao Jin   +6 more
doaj   +1 more source