Results 61 to 70 of about 2,652 (202)

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Ensemble Docking of FDA‐Approved and Peruvian Phytochemicals Against Monkeypox Virus Telomere‐Binding Protein

ChemistrySelect, Volume 11, Issue 9, 5 March 2026.
ABSTRACT Monkeypox is a reemerging zoonotic disease that has been spreading worldwide. Different approaches are being conducted to find effective treatments for this disease. To accelerate therapeutic discovery, we propose telomere‐binding protein (TBP) as a potential drug target because of its important role during virus maturation.
Edinson Gervacio‐Villarreal, Georcki Ropón‐Palacios, Claudina Sancho, Jhon Pérez‐Silva, Kewin Otazu, Gustavo E. Olivos‐Ramirez, Karolyn Vega‐Chozo, Yaritza L. Ramirez‐Díaz, Manuel E. Chenet‐Zuta, Ivonne Navarro del Aguila, Mario De la Cruz Flores, Cinthia Aguiar, Ihosvany Camps   +12 more
wiley   +1 more source

Diseño y síntesis de compuestos derivados de 2-fenilpiperazina. Nuevas ureas con potencial acción antiadenovirus [PDF]

, 2016
Los adenovirus (Adv) comprenden un gran grupo de complejos virus no envueltos, con un diámetro de 80 nm, simetría icosahédrica y ADN bicatenario. Fueron aislados por primera vez en 1953 como patógenos respiratiorios.
Martín Moreno, Rocío
core  

Clinical considerations on monkeypox antiviral medications: An overview

Pharmacology Research & Perspectives
Monkeypox (mpox), a virus belonging to the orthopoxvirus family, can cause a zoonotic infectious disease with morbidity and cosmetic complications. Therefore, effective antiviral drugs with appropriate safety profiles are important for the treatment of ...
Fariba Pourkarim, Taher Entezari‐Maleki   +1 more
doaj   +1 more source

BK virus: Current understanding of pathogenicity and clinical disease in transplantation [PDF]

, 2019
BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or ...
Antoni, M, Chong, S, Harber, M, Macdonald, A, Magee, CN, Reeves, M   +5 more
core   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

The successful treatment of mpox with brincidofovir in renal transplant recipients—a report of 2 cases

International Journal of Infectious Diseases
An mpox outbreak was declared in July 2022 by the world health organization (WHO). It causes a mild self-limiting disease however; in immunosuppressed hosts, it tends to cause severe disseminated infection.
Reem M. Alameer, Amani Yamani, Abdulrahman Al-Saud, Sultan Alsobayeg, Bayan Alamro, Alaa Alali, Ehab Hammad, Ali M. Shendi, Reem S. Almaghrabi   +8 more
doaj   +1 more source

Ebola research funding: a systematic analysis, 1997–2015

, 2016
Background: The latest outbreak of Ebola in West Africa overwhelmed the affected countries, with the impact on health extending far beyond Ebola–related deaths that have exceeded 11?000.
Atun, Rifat, Fitchett, Joseph R.A., Head, Michael, Lichtman, Amos, Low, Ariel, Soyode, Damilola T., Villar de Onis, Jimena   +6 more
core   +1 more source

Administration of Brincidofovir and Convalescent Plasma in a Patient With Ebola Virus Disease [PDF]

Clinical Infectious Diseases, 2015
From 2014 to May 2015, >26 000 Ebola virus disease (EVD) cases were reported from West Africa. We present a patient with EVD who received brincidofovir and convalescent plasma. The relative contributions of supportive care, investigational therapies, and patient's immune-response on survival could not be determined. Randomized trials are needed.
Diana F, Florescu, Andre C, Kalil, Angela L, Hewlett, Amy J, Schuh, Ute, Stroher, Timothy M, Uyeki, Philip W, Smith   +6 more
openaire   +2 more sources

Efficacy of Brincidofovir in Pediatric Stem Cell Transplant Recipients With Adenovirus Infections

Journal of the Pediatric Infectious Diseases Society, 2021
Abstract Background Adenovirus (AdV) infections are of particular concern in pediatric hematopoietic stem cell transplantation (HSCT) recipients as therapeutic options are limited. Brincidofovir (BCV) is the lipid-conjugated pro-drug of cidofovir (CDV) with oral bioavailability and higher ...
Karoline Ehlert, Johannes H Schulte, Jörn-Sven Kühl, Peter Lang, Angelika Eggert, Sebastian Voigt   +5 more
openaire   +2 more sources