Results 51 to 60 of about 2,652 (202)

A REVIEW OF MONKEYPOX DISEASE AND FUTURE TREATMENT OPTIONS [PDF]

, 2023
The Monkeypox virus (MPXV) causative agent for Monkeypox disease resembles a smallpox-like illness and can lead to a number of serious medical issues in humans.
MISRA, SAURAV, SHUKLA, AJAY KUMAR
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Diseño, síntesis y caracterización estructural de compuestos derivados de 2-amino-propano-1,3-diol potencialmente activos como antivirales [PDF]

, 2019
Los adenovirus (AdV) son virus eucariotas con 36000 pares de bases, producen infecciones que son muy comunes y se dan durante todo el año. Las poblaciones susceptibles a la infección por adenovirus (AdV) incluyen niños, pacientes inmunocomprometidos y ...
Muriana Camacho, Claudia
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Effect of brincidofovir on adenovirus and A549 cells transcriptome profiles

Antiviral Research, 2020
Human adenovirus (HAdV) infections are associated with a high morbidity and mortality in transplant patients requiring the use of antiviral treatments. Brincidofovir (BCV), a cytidine analog, inhibits HAdV replication through viral DNA elongation termination and likely through other mechanisms. To elucidate if BCV regulates cellular antiviral pathways,
Salmona, Maud, Feghoul, Linda, Mercier-Delarue, Séverine, Diaz, Elise, Splitberger, Marion, Armero, Alix, Dalle, Jean-Hugues, Dutrieux, Jacques, Legoff, Jérôme   +8 more
openaire   +2 more sources

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

British Journal of Pharmacology, Volume 183, Issue 7, Page 1578-1601, April 2026.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy, Sophie Post, Wing Hang Ip, Elin Hahlin, Sebastian Kühn, Andrea Pirosu, Christian Conze, Martin Baumdick, Hamburg Intestinal Study Group, Madeleine J. Bunders, Britta F. Zecher, Angelique Hoelzemer, Stephan Linder, Niklas Arnberg, Thomas Dobner, Marcus Altfeld, Sebastian Schloer   +16 more
wiley   +1 more source

Clinical Strategies and Therapeutics for Human Monkeypox Virus: A Revised Perspective on Recent Outbreaks

Viruses, 2023
An enveloped double-stranded DNA monkeypox virus (MPXV) is a causative agent of the zoonotic viral disease, human monkeypox (HMPX). MPXV belongs to the genus Orthopoxviridae, a family of notorious smallpox viruses, and so it shares similar clinical ...
Nilanjan Ghosh, Leena Chacko, Jayalakshmi Vallamkondu, Tanmoy Banerjee, Chandrima Sarkar, Birbal Singh, Rajkumar Singh Kalra, Jasvinder Singh Bhatti, Ramesh Kandimalla, Saikat Dewanjee   +9 more
doaj   +1 more source

Detection of adenovirus hepatitis and acute liver failure in allogeneic hematopoietic stem cell transplant patients [PDF]

, 2021
Human adenovirus (HAdV) is an important cause of the common cold and epidemic keratoconjunctivitis in immunocompetent individuals. In immunocompromised patients, HAdV can sometimes cause severe infection such as cystitis, gastroenteritis, pneumonia ...
Anzai, Naoyuki, Fujimoto, Tsuguto, Haga, Hironori, Hanaoka, Nozomu, Kanda, Junya, Okada, Mutsumi, Onda, Yoshiyuki, Sakamoto, Soichiro, Takaori-Kondo, Akifumi, Tashima, Masaro, Umadome, Hiroshi, Watanabe, Chihiro   +11 more
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Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

mSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson, Ashley V. Kondas, Mathew R. Mauldin, Jeffrey B. Doty, Irma M. Grossi, Clint N. Morgan, Sharon Dietz Ostergaard, Christine M. Hughes, Yoshinori Nakazawa, Chantal Kling, Brock E. Martin, James A. Ellison, Darin D. Carroll, Nadia F. Gallardo-Romero, Victoria A. Olson   +14 more
doaj   +1 more source

Monkeypox (Mpox) requires continued surveillance, vaccines, therapeutics and mitigating strategies [PDF]

, 2023
The widespread outbreak of the monkeypox virus (MPXV) recognized in 2022 poses new challenges for public healthcare systems worldwide. With more than 86,000 people infected, there is concern that MPXV may become endemic outside of its original ...
Abimiku, Alash'le, Bréchot, Christian, Del Rio, Carlos, Esparza, José, Gallo, Robert, Garzino-Demo, Alfredo, Gessain, Antoine, Hall, William, Huan, Tan Boon, Isaacs, Stuart N, Koopmans, Marion, LeDuc, James, Mahalingam, Suresh, McFadden, Grant, Nitsche, Andreas, Osorio, Jorge, Osterhaus, Albert, Parrington, Mark, Reitz, Marvin, Roper, Rachel L., Scheuermann, Richard H., Schinazi, Raymond F., Segalés, Joaquim, Tartaglia, James, Vahlne, Anders, Wang, Linfa, Weaver, Scott   +26 more
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Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

JEADV Clinical Practice, Volume 5, Issue 1, Page 250-253, March 2026.
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González, Sergio López Alcázar, José Ángel Amat Sánchez, Francisco Vergara Barria, Rosa Feltes Ochoa, Elena Sendagorta Cudos, Pedro Herranz Pinto   +6 more
wiley   +1 more source

Farmacomodulación de ureas derivadas de piperazina con actividad antiadenovirus. Síntesis y caracterización estructural [PDF]

, 2018
Los adenovirus humanos (HAdVs) son patógenos pertenecientes a la familia Adenoviridae. Actualmente se han logrado identificar más de 60 serotipos distintos del virus, distribuidos en siete especies (A-G) que se diferencian entre sí en el tipo de ...
Medina Payán, Sandra
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