Results 41 to 50 of about 1,885 (156)

Rapid Virologic Response to Brincidofovir in Children with Disseminated Adenovirus Infection

Infection & Chemotherapy, 2021
Disseminated adenovirus infections (d-ADV) after hematopoietic cell transplant (HCT) are often fatal with limited treatment options. Brincidofovir (BCV) a lipid ester of cidofovir is developed for this indication. We report four pediatric HCT recipients with d-ADV treated successfully with BCV.
Shuk Ying Chan, Susan E. Prockop, Farid Boulad, Genovefa A. Papanicolaou, Yeon Joo Lee   +4 more
openaire   +2 more sources

Monkeypox – An emerging pandemic

IDCases, 2022
Monkeypox–a zoonotic disease caused by the monkeypox virus, an orthopoxviruses family member. Recently monkeypox cases are increasing at an alarming rate in the US and worldwide.
Kunal M. Ajmera, Lokesh Goyal, Trupti Pandit, Ramesh Pandit   +3 more
doaj   +1 more source

Is photodynamic therapy with curcumin suitable for combating monkeypox?

Infectious Diseases and Herbal Medicine, 2023
Monkeypox (MPX) is a zoonotic viral infection caused by the Monkeypox Virus (MPXV), which may spread person-to-person directly. It is currently being treated with previously intended drugs for smallpox or other diseases caused by the orthopoxvirus, such
Siu Kan Law
doaj   +1 more source

Early Mpox Detection: Integrating Skin Lesion Imaging, Epidemiology, and Treatment for Deep Learning Approaches

Medicine Advances, Volume 4, Issue 3, Page 287-296, September 2026.
Research papers utilizing publicly available, web‐scraped resources related to mpox—including news portals and datasets such as Monkeypox2022, Kaggle, and the Monkeypox Skin Images Dataset—demonstrate variability in accuracy. Our findings suggest that although deep learning models such as MobileNetV2, VGG16, and GoogLeNet report accuracy exceeding 95%,
Taskin Sabit, Faiza Tasnim
wiley   +1 more source

Drug Repurposing for Monkeypox: An Alternative Strategy for Emergency Response

JPSCR: Journal of Pharmaceutical Science and Clinical Research
The global monkeypox (MPOX) outbreak, which has resulted in more than 100,000 confirmed cases across over 120 countries, underscores the urgent need for effective therapeutic strategies. MPOX, caused by a virus belonging to the Orthopoxvirus genus, poses
Luthfi Harbulcholizi, Jekmal Malau, Ihsan Alfiandri, Iqbal Zulkifli, Ratika Rahmasari   +4 more
doaj   +1 more source

Human monkeypox: a comparison of the characteristics of the new epidemic to the endemic disease

BMC Infectious Diseases, 2022
In May 2022, a new global outbreak of mpox (formerly, human monkeypox) emerged that was declared a public health emergency of international concern by the World Health Organization on July 23, 2022.
Sharon Sukhdeo, Sharmistha Mishra, Sharon Walmsley   +2 more
doaj   +1 more source

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo, Fisseha Assegidew Gebretsadik, Abyou Seyfu Ambaye, Bedilu Linger Endalifer, Teshome Fentik Belachew   +4 more
wiley   +1 more source

Effect of brincidofovir on adenovirus and A549 cells transcriptome profiles

Antiviral Research, 2020
Human adenovirus (HAdV) infections are associated with a high morbidity and mortality in transplant patients requiring the use of antiviral treatments. Brincidofovir (BCV), a cytidine analog, inhibits HAdV replication through viral DNA elongation termination and likely through other mechanisms. To elucidate if BCV regulates cellular antiviral pathways,
Salmona, Maud, Feghoul, Linda, Mercier-Delarue, Séverine, Diaz, Elise, Splitberger, Marion, Armero, Alix, Dalle, Jean-Hugues, Dutrieux, Jacques, Legoff, Jérôme   +8 more
openaire   +2 more sources

Clinical considerations on monkeypox antiviral medications: An overview

Pharmacology Research & Perspectives
Monkeypox (mpox), a virus belonging to the orthopoxvirus family, can cause a zoonotic infectious disease with morbidity and cosmetic complications. Therefore, effective antiviral drugs with appropriate safety profiles are important for the treatment of ...
Fariba Pourkarim, Taher Entezari‐Maleki   +1 more
doaj   +1 more source

Clinical Strategies and Therapeutics for Human Monkeypox Virus: A Revised Perspective on Recent Outbreaks

Viruses, 2023
An enveloped double-stranded DNA monkeypox virus (MPXV) is a causative agent of the zoonotic viral disease, human monkeypox (HMPX). MPXV belongs to the genus Orthopoxviridae, a family of notorious smallpox viruses, and so it shares similar clinical ...
Nilanjan Ghosh, Leena Chacko, Jayalakshmi Vallamkondu, Tanmoy Banerjee, Chandrima Sarkar, Birbal Singh, Rajkumar Singh Kalra, Jasvinder Singh Bhatti, Ramesh Kandimalla, Saikat Dewanjee   +9 more
doaj   +1 more source