Results 41 to 50 of about 1,825 (158)

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo, Fisseha Assegidew Gebretsadik, Abyou Seyfu Ambaye, Bedilu Linger Endalifer, Teshome Fentik Belachew   +4 more
wiley   +1 more source

Drug Repurposing for Monkeypox: An Alternative Strategy for Emergency Response

JPSCR: Journal of Pharmaceutical Science and Clinical Research
The global monkeypox (MPOX) outbreak, which has resulted in more than 100,000 confirmed cases across over 120 countries, underscores the urgent need for effective therapeutic strategies. MPOX, caused by a virus belonging to the Orthopoxvirus genus, poses
Luthfi Harbulcholizi, Jekmal Malau, Ihsan Alfiandri, Iqbal Zulkifli, Ratika Rahmasari   +4 more
doaj   +1 more source

Human monkeypox: a comparison of the characteristics of the new epidemic to the endemic disease

BMC Infectious Diseases, 2022
In May 2022, a new global outbreak of mpox (formerly, human monkeypox) emerged that was declared a public health emergency of international concern by the World Health Organization on July 23, 2022.
Sharon Sukhdeo, Sharmistha Mishra, Sharon Walmsley   +2 more
doaj   +1 more source

Effect of brincidofovir on adenovirus and A549 cells transcriptome profiles

Antiviral Research, 2020
Human adenovirus (HAdV) infections are associated with a high morbidity and mortality in transplant patients requiring the use of antiviral treatments. Brincidofovir (BCV), a cytidine analog, inhibits HAdV replication through viral DNA elongation termination and likely through other mechanisms. To elucidate if BCV regulates cellular antiviral pathways,
Salmona, Maud, Feghoul, Linda, Mercier-Delarue, Séverine, Diaz, Elise, Splitberger, Marion, Armero, Alix, Dalle, Jean-Hugues, Dutrieux, Jacques, Legoff, Jérôme   +8 more
openaire   +2 more sources

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

British Journal of Pharmacology, Volume 183, Issue 7, Page 1578-1601, April 2026.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy, Sophie Post, Wing Hang Ip, Elin Hahlin, Sebastian Kühn, Andrea Pirosu, Christian Conze, Martin Baumdick, Hamburg Intestinal Study Group, Madeleine J. Bunders, Britta F. Zecher, Angelique Hoelzemer, Stephan Linder, Niklas Arnberg, Thomas Dobner, Marcus Altfeld, Sebastian Schloer   +16 more
wiley   +1 more source

Clinical considerations on monkeypox antiviral medications: An overview

Pharmacology Research & Perspectives
Monkeypox (mpox), a virus belonging to the orthopoxvirus family, can cause a zoonotic infectious disease with morbidity and cosmetic complications. Therefore, effective antiviral drugs with appropriate safety profiles are important for the treatment of ...
Fariba Pourkarim, Taher Entezari‐Maleki   +1 more
doaj   +1 more source

Clinical Strategies and Therapeutics for Human Monkeypox Virus: A Revised Perspective on Recent Outbreaks

Viruses, 2023
An enveloped double-stranded DNA monkeypox virus (MPXV) is a causative agent of the zoonotic viral disease, human monkeypox (HMPX). MPXV belongs to the genus Orthopoxviridae, a family of notorious smallpox viruses, and so it shares similar clinical ...
Nilanjan Ghosh, Leena Chacko, Jayalakshmi Vallamkondu, Tanmoy Banerjee, Chandrima Sarkar, Birbal Singh, Rajkumar Singh Kalra, Jasvinder Singh Bhatti, Ramesh Kandimalla, Saikat Dewanjee   +9 more
doaj   +1 more source

Mpox (Monkeypox) in Pregnancy Updates

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Yeshey Dorjey, Deep Kiran Chhetri
wiley   +1 more source

Efficacy of Brincidofovir in Pediatric Stem Cell Transplant Recipients With Adenovirus Infections

Journal of the Pediatric Infectious Diseases Society, 2021
Abstract Background Adenovirus (AdV) infections are of particular concern in pediatric hematopoietic stem cell transplantation (HSCT) recipients as therapeutic options are limited. Brincidofovir (BCV) is the lipid-conjugated pro-drug of cidofovir (CDV) with oral bioavailability and higher ...
Karoline Ehlert, Johannes H Schulte, Jörn-Sven Kühl, Peter Lang, Angelika Eggert, Sebastian Voigt   +5 more
openaire   +2 more sources

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

JEADV Clinical Practice, Volume 5, Issue 1, Page 250-253, March 2026.
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González, Sergio López Alcázar, José Ángel Amat Sánchez, Francisco Vergara Barria, Rosa Feltes Ochoa, Elena Sendagorta Cudos, Pedro Herranz Pinto   +6 more
wiley   +1 more source