Results 31 to 40 of about 1,825 (158)
Clinical features and management of human monkeypox [PDF]
Scripta Medica, 2023 The COVID-19 pandemic is abating, but the threat of a new epidemic is growing due to the spread of monkeypox in non-endemic regions of the world. In 2022, there were the monkeypox outbreaks throughout Europe, in the Western Hemisphere. With the cessation
Moisova Diana L. +5 more
doaj
Frontiers in Pharmacology, 2023 Mpox (earlier known as monkeypox) virus infection is a recognized public health emergency. There has been little research on the treatment options. This article reviews the specific drugs used to treat mpox virus infection and the vaccines used here ...
Muhammad Aaqib Shamim +21 more
doaj +1 more source
Identification of In Vitro Inhibitors of Monkeypox Replication
Microbiology Spectrum, 2023 Monkeypox virus (MPXV) infections in humans have historically been restricted to regions of endemicity in Africa. However, in 2022, an alarming number of MPXV cases were reported globally, with evidence of person-to-person transmission.
Kevin Chiem +8 more
doaj +1 more source
Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents
Microbiology Spectrum, 2023 Mpox virus (formerly monkeypox virus [MPXV]) is a neglected zoonotic pathogen that caused a worldwide outbreak in May 2022. Given the lack of an established therapy, the development of an anti-MPXV strategy is of vital importance.
Takayuki Hishiki +20 more
doaj +1 more source
In Vitro Efficacy of Brincidofovir against Variola Virus [PDF]
Antimicrobial Agents and Chemotherapy, 2014 ABSTRACT Brincidofovir (CMX001), a lipid conjugate of the acyclic nucleotide phosphonate cidofovir, is under development for smallpox treatment using “the Animal Rule,” established by the FDA in 2002. Brincidofovir reduces mortality caused by orthopoxvirus infection in animal models.
Victoria A, Olson +7 more
openaire +2 more sources
Antiviral Drugs for Treatment of Human Monkeypox: A Systematic Review/Meta-analysis
Microbes, Infection and ChemotherapyBackground. On 23 July 2022, the World Health Organization declared a Public Health Emergency of International Concern. Monkeypox is a zoonotic viral disease caused by the monkeypox virus that is transmitted from animals to humans or from human to human.
Ahmed Mohamed Abdelghany +2 more
doaj +1 more source
Monkeypox – An emerging pandemic
IDCases, 2022 Monkeypox–a zoonotic disease caused by the monkeypox virus, an orthopoxviruses family member. Recently monkeypox cases are increasing at an alarming rate in the US and worldwide.
Kunal M. Ajmera +3 more
doaj +1 more source
Administration of Brincidofovir and Convalescent Plasma in a Patient With Ebola Virus Disease [PDF]
Clinical Infectious Diseases, 2015 From 2014 to May 2015, >26 000 Ebola virus disease (EVD) cases were reported from West Africa. We present a patient with EVD who received brincidofovir and convalescent plasma. The relative contributions of supportive care, investigational therapies, and patient's immune-response on survival could not be determined. Randomized trials are needed.
Diana F, Florescu +6 more
openaire +2 more sources
Rapid Virologic Response to Brincidofovir in Children with Disseminated Adenovirus Infection
Infection & Chemotherapy, 2021 Disseminated adenovirus infections (d-ADV) after hematopoietic cell transplant (HCT) are often fatal with limited treatment options. Brincidofovir (BCV) a lipid ester of cidofovir is developed for this indication. We report four pediatric HCT recipients with d-ADV treated successfully with BCV.
Shuk Ying Chan +4 more
openaire +2 more sources
Is photodynamic therapy with curcumin suitable for combating monkeypox?
Infectious Diseases and Herbal Medicine, 2023 Monkeypox (MPX) is a zoonotic viral infection caused by the Monkeypox Virus (MPXV), which may spread person-to-person directly. It is currently being treated with previously intended drugs for smallpox or other diseases caused by the orthopoxvirus, such
Siu Kan Law
doaj +1 more source