Clinical features and management of human monkeypox [PDF]
Scripta Medica, 2023 The COVID-19 pandemic is abating, but the threat of a new epidemic is growing due to the spread of monkeypox in non-endemic regions of the world. In 2022, there were the monkeypox outbreaks throughout Europe, in the Western Hemisphere. With the cessation
Moisova Diana L. +5 more
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Advances in the Development of Antiviral Strategies against Parvovirus B19
Viruses, 2019 Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of clinical manifestations. Infections are usually mild, self-limiting, and controlled by the development of a specific immune response, but in many cases clinical ...
Elisabetta Manaresi, Giorgio Gallinella
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Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters [PDF]
, 2015 Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections. Cidofovir (an analog of 2-deoxycytidine
Balakrishnan, Lata +7 more
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Frontiers in Pharmacology, 2023 Mpox (earlier known as monkeypox) virus infection is a recognized public health emergency. There has been little research on the treatment options. This article reviews the specific drugs used to treat mpox virus infection and the vaccines used here ...
Muhammad Aaqib Shamim +21 more
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Monkeypox: A Contemporary Review for Healthcare Professionals [PDF]
, 2022 The ongoing 2022 multicountry outbreak of monkeypox is the largest in history to occur outside of Africa. Monkeypox is an emerging zoonotic disease that for decades has been viewed as an infectious disease with significant epidemic potential because of ...
Konomos, Michael +4 more
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Identification of In Vitro Inhibitors of Monkeypox Replication
Microbiology Spectrum, 2023 Monkeypox virus (MPXV) infections in humans have historically been restricted to regions of endemicity in Africa. However, in 2022, an alarming number of MPXV cases were reported globally, with evidence of person-to-person transmission.
Kevin Chiem +8 more
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Anti-adenoviral artificial microRNAs Expressed from AAV9 vectors inhibit human adenovirus infection in immunosuppressed Syrian hamsters [PDF]
, 2017 Infections of immunocompromised patients with human adenoviruses (hAd) can develop into life-threatening conditions, whereas drugs with anti-adenoviral efficiency are not clinically approved and have limited efficacy.
Fechner, Henry +12 more
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Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents
Microbiology Spectrum, 2023 Mpox virus (formerly monkeypox virus [MPXV]) is a neglected zoonotic pathogen that caused a worldwide outbreak in May 2022. Given the lack of an established therapy, the development of an anti-MPXV strategy is of vital importance.
Takayuki Hishiki +20 more
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Mpox (Formally Known as Monkeypox) [PDF]
, 2023 Mpox originates from the Mpox virus, which belongs to the Orthopoxvirus genus of the Poxviridae family.1, 2, 3 Other Orthopoxvirus species include the variola virus (the now eradicated smallpox virus), vaccinia virus (a virus used in the creation of the ...
Bester, Vanessa +5 more
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Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry [PDF]
, 2015 Emerging viral diseases pose a threat to the global population as intervention strategies are mainly limited to basic containment due to the lack of efficacious and approved vaccines and antiviral drugs.
A De Milito +65 more
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