Results 21 to 30 of about 1,825 (158)

Antivirals against Monkeypox (Mpox) in Humans: An Updated Narrative Review

Life, 2023
As of 29 August 2023, a total of 89,596 confirmed cases of Mpox (monkeypox) have been documented across 114 countries worldwide, with 157 reported fatalities.
Giuseppe Bruno, Giovanni Battista Buccoliero   +1 more
doaj   +1 more source

Sensitivity of Human Mastadenovirus, the Causal Agent of Pharyngoconjunctival Fever, Epidemic Keratoconjunctivitis, and Hemorrhagic Cystitis in Immunocompromised Individuals, to Brincidofovir

Microbiology Spectrum, 2022
Human mastadenovirus (HAdV), a linear double-stranded DNA (dsDNA) virus, is the causal agent of several diseases, including pharyngoconjunctival fever, epidemic keratoconjunctivitis, and hemorrhagic cystitis, in immunocompromised individuals.
Nozomu Hanaoka, Masatoshi Hazama, Koji Fukushima, Tsuguto Fujimoto   +3 more
doaj   +1 more source

Repositioning potentials of smallpox vaccines and antiviral agents in monkeypox outbreak: A rapid review on comparative benefits and risks

Health Science Reports, 2022
Background and aims There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on ...
Md. Rabiul Islam, Md. Jamal Hossain, Arpita Roy, A. H. M. Nazmul Hasan, Md. Ashrafur Rahman, Mohammad Shahriar, Mohiuddin Ahmed Bhuiyan   +6 more
doaj   +1 more source

Disseminated adenovirus infection twenty-five years post heart-lung transplant complicated by haemophagocytic lymphohistiocytosis

Clinical Infection in Practice, 2021
Disseminated adenovirus infection is well recognised in transplant patients and carries a high mortality. Treatment options are limited and potentially hepatotoxic and nephrotoxic.
Ramu Vathenen, Sakib Rokadiya, Jonathan Lambourne   +2 more
doaj   +1 more source

Comparison of the binding energies of approved mpox drugs and phytochemicals through molecular docking, molecular dynamics simulation, and ADMET studies: An in silico approach

Journal of Biosafety and Biosecurity, 2023
The mpox (previously monkeypox) outbreak in more than 100 non-endemic countries in 2022 posed a serious global health concern. Mpox is emerging as a global public health threat from a seemingly neglected disease.
Ranjan K. Mohapatra, Ahmed Mahal, Azaj Ansari, Manjeet Kumar, Jyoti Prakash Guru, Ashish K. Sarangi, Aly Abdou, Snehasish Mishra, Mohammed Aljeldah, Bashayer M. AlShehail, Mohammed Alissa, Mohammed Garout, Ahmed Alsayyah, Ahmad A. Alshehri, Ahmed Saif, Abdulaziz Alqahtani, Fahd A. Alshehri, Aref A. Alamri, Ali A. Rabaan   +18 more
doaj   +1 more source

The use of antivirals in the treatment of human monkeypox outbreaks: a systematic review

International Journal of Infectious Diseases, 2023
Objectives: Human monkeypox virus (MPXV) infection is a recently declared public health emergency of international concern by the World Health Organization. Besides, there is scant literature available on the use of antivirals in MPXV infection.
Muhammad Aaqib Shamim, Bijaya Kumar Padhi, Prakasini Satapathy, Sai D Veeramachaneni, Chandrima Chatterjee, Snehasish Tripathy, Naushaba Akhtar, Anindita Pradhan, Pradeep Dwivedi, Aroop Mohanty, Alfonso J. Rodriguez-Morales, Ranjit Sah, Ala'a B. Al-Tammemi, Jaffar A. Al-Tawfiq, Behdin Nowrouzi-Kia, Vijay Kumar Chattu   +15 more
doaj   +1 more source

A brief on new waves of monkeypox and vaccines and antiviral drugs for monkeypox

Journal of Microbiology, Immunology and Infection, 2022
Monkeypox virus (MPXV), genetic closely linked to the notorious variola (smallpox) virus, currently causes several clusters and outbreaks in the areas outside Africa and is noted to be phylogenetically related to the West African clade.
Yuan-Pin Hung, Ching-Chi Lee, Jen-Chieh Lee, Chun-Wei Chiu, Po-Ren Hsueh, Wen-Chien Ko   +5 more
doaj   +1 more source

Disseminated Adenovirus Infection After Combined Liver-Kidney Transplantation

Frontiers in Cellular and Infection Microbiology, 2018
Human adenovirus (HAdV) infections are well-described after hematopoietic stem cell transplantation but less well understood in solid organ transplantation (SOT).
Marion Hemmersbach-Miller, Marion Hemmersbach-Miller, Emily S. Bailey, Matthew Kappus, Vinod K. Prasad, Gregory C. Gray, J. Andrew Alspaugh   +6 more
doaj   +1 more source

Successful Treatment of Adenovirus Infection with Brincidofovir in an Immunocompromised Patient after Hematological Stem Cell Transplantation

Case Reports in Infectious Diseases, 2020
Immunocompromised patients, including hematopoietic stem cell transplantation (HSCT), HIV, and malnourished patients, are at increased risk for viral infections with high incidences of morbidity and mortality.
T. Van Genechten, J. van Heerden, T. Bauters, C. Dhooge   +3 more
doaj   +1 more source

Advances in the Development of Antiviral Strategies against Parvovirus B19

Viruses, 2019
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of clinical manifestations. Infections are usually mild, self-limiting, and controlled by the development of a specific immune response, but in many cases clinical ...
Elisabetta Manaresi, Giorgio Gallinella
doaj   +1 more source