Results 21 to 30 of about 2,652 (202)

Ebola Virus Infection: Overview and Update on Prevention and Treatment [PDF]

, 2015
In 2014 and 2015, the largest Ebola virus disease (EVD) outbreak in history affected large populations across West Africa. The goal of this report is to provide an update on the epidemic and review current progress in the development, evaluation and ...
Hurtado, Juan C., Kilgore, Paul E., Martínez, Miguel J., Salim, Abdulbaset M.   +3 more
core   +4 more sources

Modernising epidemic science: enabling patient-centred research during epidemics [PDF]

, 2016
Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core   +5 more sources

Sensitivity of Human Mastadenovirus, the Causal Agent of Pharyngoconjunctival Fever, Epidemic Keratoconjunctivitis, and Hemorrhagic Cystitis in Immunocompromised Individuals, to Brincidofovir

Microbiology Spectrum, 2022
Human mastadenovirus (HAdV), a linear double-stranded DNA (dsDNA) virus, is the causal agent of several diseases, including pharyngoconjunctival fever, epidemic keratoconjunctivitis, and hemorrhagic cystitis, in immunocompromised individuals.
Nozomu Hanaoka, Masatoshi Hazama, Koji Fukushima, Tsuguto Fujimoto   +3 more
doaj   +1 more source

Repositioning potentials of smallpox vaccines and antiviral agents in monkeypox outbreak: A rapid review on comparative benefits and risks

Health Science Reports, 2022
Background and aims There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on ...
Md. Rabiul Islam, Md. Jamal Hossain, Arpita Roy, A. H. M. Nazmul Hasan, Md. Ashrafur Rahman, Mohammad Shahriar, Mohiuddin Ahmed Bhuiyan   +6 more
doaj   +1 more source

Disseminated adenovirus infection twenty-five years post heart-lung transplant complicated by haemophagocytic lymphohistiocytosis

Clinical Infection in Practice, 2021
Disseminated adenovirus infection is well recognised in transplant patients and carries a high mortality. Treatment options are limited and potentially hepatotoxic and nephrotoxic.
Ramu Vathenen, Sakib Rokadiya, Jonathan Lambourne   +2 more
doaj   +1 more source

Comparison of the binding energies of approved mpox drugs and phytochemicals through molecular docking, molecular dynamics simulation, and ADMET studies: An in silico approach

Journal of Biosafety and Biosecurity, 2023
The mpox (previously monkeypox) outbreak in more than 100 non-endemic countries in 2022 posed a serious global health concern. Mpox is emerging as a global public health threat from a seemingly neglected disease.
Ranjan K. Mohapatra, Ahmed Mahal, Azaj Ansari, Manjeet Kumar, Jyoti Prakash Guru, Ashish K. Sarangi, Aly Abdou, Snehasish Mishra, Mohammed Aljeldah, Bashayer M. AlShehail, Mohammed Alissa, Mohammed Garout, Ahmed Alsayyah, Ahmad A. Alshehri, Ahmed Saif, Abdulaziz Alqahtani, Fahd A. Alshehri, Aref A. Alamri, Ali A. Rabaan   +18 more
doaj   +1 more source

The use of antivirals in the treatment of human monkeypox outbreaks: a systematic review

International Journal of Infectious Diseases, 2023
Objectives: Human monkeypox virus (MPXV) infection is a recently declared public health emergency of international concern by the World Health Organization. Besides, there is scant literature available on the use of antivirals in MPXV infection.
Muhammad Aaqib Shamim, Bijaya Kumar Padhi, Prakasini Satapathy, Sai D Veeramachaneni, Chandrima Chatterjee, Snehasish Tripathy, Naushaba Akhtar, Anindita Pradhan, Pradeep Dwivedi, Aroop Mohanty, Alfonso J. Rodriguez-Morales, Ranjit Sah, Ala'a B. Al-Tammemi, Jaffar A. Al-Tawfiq, Behdin Nowrouzi-Kia, Vijay Kumar Chattu   +15 more
doaj   +1 more source

A brief on new waves of monkeypox and vaccines and antiviral drugs for monkeypox

Journal of Microbiology, Immunology and Infection, 2022
Monkeypox virus (MPXV), genetic closely linked to the notorious variola (smallpox) virus, currently causes several clusters and outbreaks in the areas outside Africa and is noted to be phylogenetically related to the West African clade.
Yuan-Pin Hung, Ching-Chi Lee, Jen-Chieh Lee, Chun-Wei Chiu, Po-Ren Hsueh, Wen-Chien Ko   +5 more
doaj   +1 more source

Mpox (Monkeypox) in Pregnancy Updates. [PDF]

Health Sci Rep
ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Dorjey Y, Chhetri DK.
europepmc   +2 more sources

Ebola Virus Infection: a review on the pharmacokinetic and pharmacodynamic properties of drugs considered for testing in human efficacy trials [PDF]

, 2016
International audienceThe 2014-2015 outbreak of Ebola virus disease (EVD) is the largest epidemic to date in terms of number of cases, of death and affected areas. In October 2015, no antiviral agents had proven an antiviral efficacy in patients. However
De Lamballerie, Xavier, Guedj, Jeremie, Madelain, Vincent, Mentré, France, Nguyen, Thi Huyen Tram, Olivo, Anaelle, Taburet, Anne-Marie   +6 more
core   +3 more sources