Results 31 to 40 of about 27,094 (219)
Journal of Integrative Agriculture, 2020 FgGCN5, a GCN5 homolog in Fusarium graminearum, plays a critical role in hyphal vegetative growth, asexual and sexual reproduction, deoxynivalenol (DON) biosynthesis and plant infection.
Qian-nan WANG +2 more
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Reading More than Histones: The Prevalence of Nucleic Acid Binding among Reader Domains
Molecules, 2018 The eukaryotic genome is packaged into the cell nucleus in the form of chromatin, a complex of genomic DNA and histone proteins. Chromatin structure regulation is critical for all DNA templated processes and involves, among many things, extensive post ...
Tyler M. Weaver +2 more
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TRPM3-Induced Gene Transcription Is under Epigenetic Control
Pharmaceuticals, 2022 Transient receptor potential M3 (TRPM3) cation channels regulate numerous biological functions, including gene transcription. Stimulation of TRPM3 channels with pregnenolone sulfate activates stimulus-responsive transcription factors, which bind to short
Gerald Thiel, Oliver G. Rössler
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Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma Cruzi [PDF]
, 2020 The Trypanosoma cruzi (T. cruzi) parasite is the cause of Chagas disease, a neglected disease endemic in South America. The life cycle of the T. cruzi parasite is complex and includes transitions between distinct life stages.
Andrew, Boczek +13 more
core +2 more sources
Frontiers in Molecular Biosciences, 2020 Bromodomain and extra-terminal domain (BET) family proteins have become a hot research area because of their close relationship with a variety of human diseases.
Ping Bai +9 more
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The bromodomain a chromatin browser
Frontiers in Bioscience, 2001 Reversible modification of histone tails is a regulatory step in chromatin remodeling. The N-terminal tails of histones are signaling platforms that carry amino acid residues for post-translational modification and contribute to chromosomal higher order structure. These modifications are performed by a number of chromatin modulators such as histone (h)
FILETICI P., ORNAGHI P., BALLARIO, Paola
openaire +5 more sources
Frontiers in Cell and Developmental Biology, 2022 Epigenetic regulation is a critical mechanism in controlling virulence, differentiation, and survival of the human malaria parasite Plasmodium (P.) falciparum.
Jennifer E. Quinn +10 more
doaj +1 more source
BRD3 (bromodomain containing 3) [PDF]
, 2016 BRD3 is a ubiquitously expressed member of the bromodomain and extraterminal motif (BET) family of proteins that use their tandem N-terminal bromodomains to associate with acetylated histones and transcription factors.
Blobel, Gerd A +2 more
core +1 more source
Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle
Viruses, 2013 The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4.
Moon Kyoo Jang, Alison A. McBride
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Pharmaceuticals, 2022 Crescentic glomerulonephritis is a devastating autoimmune disease that without early and properly treatment may rapidly progress to end-stage renal disease and death.
Lucia Tejedor-Santamaria +13 more
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