Results 51 to 60 of about 67,551 (154)

A theoretical model of the application of RF energy to the airway wall and its experimental validation

BioMedical Engineering OnLine, 2010
Background Bronchial thermoplasty is a novel technique designed to reduce an airway's ability to contract by reducing the amount of airway smooth muscle through controlled heating of the airway wall.
Brown Robert H, Wizeman Bill, Jarrard Jerry, Mitzner Wayne   +3 more
doaj   +1 more source

Effectiveness of mepolizumab for eosinophilic pneumonia following bronchial thermoplasty

Respirology Case Reports, 2020
A 57‐year‐old woman with poorly controlled diabetes was admitted to our hospital for additional treatment of severe asthma. Although bronchial thermoplasty was performed in the both upper lobes, cough and dyspnoea gradually appeared 2 weeks later.
Ryota Otoshi, Tomohisa Baba, Shigeru Komatsu, Masato Asaoka, Eri Hagiwara, Takashi Ogura   +5 more
doaj   +1 more source

Bronchial thermoplasty for severe asthma: A position statement of the Indian chest society

Lung India, 2020
Bronchial thermoplasty (BT) is an interventional bronchoscopic treatment for severe asthma. There is a need to define patient selection criteria to guide clinicians in offering the appropriate treatment options to patients with severe asthma. Methodology:
Karan Madan, Saurabh Mittal, Tejas M Suri, Avinash Jain, Anant Mohan, Vijay Hadda, Pavan Tiwari, Randeep Guleria, Deepak Talwar, Sudhir Chaudhri, Virendra Singh, Rajesh Swarnakar, Sachidanand J Bharti, Rakesh Garg, Nishkarsh Gupta, Vinod Kumar, Ritesh Agarwal, Ashutosh N Aggarwal, Irfan I Ayub, Prashant N Chhajed, Amit Dhamija, Raja Dhar, Sahajal Dhooria, Hari K Gonuguntla, Rajiv Goyal, Parvaiz A Koul, Raj Kumar, Nagarjuna Maturu, Ravindra M Mehta, Ujjwal Parakh, Vallandaramam Pattabhiraman, Narasimhan Raghupathi, Inderpaul Singh Sehgal, Arjun Srinivasan, Kavitha Venkatnarayan   +34 more
doaj   +1 more source

Patterns and Clinical Efficacy of Biologics Switching in Patients With Severe Asthma: A Systematic Review and Meta‐Analysis

Allergy, Volume 81, Issue 5, Page 1548-1570, May 2026.
This meta‐analysis included 2292 patients with severe asthma who underwent biologic switching across 23 countries/regions. The most prevalent switching pattern was from mepolizumab to benralizumab, with suboptimal asthma control being the primary reason.
Yang Zheng, Ya‐chun Li, Sheng‐jie Li, Meng Xu, Jia‐qian Hu, Wen‐qu Tian, Shi‐wei Chen, Xue‐hui Li, Ying He, Gan Lu, Mübeccel Akdis, Ioana Agache, Cezmi A. Akdis, Ya‐dong Gao   +13 more
wiley   +1 more source

Decoding Asthma Therapy: The Role of VEGFA and HIF1A in Yanghe Pingchuan Granule's Mechanism

IET Systems Biology, Volume 20, Issue 1, January/December 2026.
YPG combats asthma by targeting glycolysis‐related genes GSTP1, VEGFA and HIF1A, validated through network pharmacology and experiments. Molecular docking confirms strong binding of its core compounds to these targets, and in vivo studies show YPG significantly reduces their expression.
Qiuping Zhang, Huizhi Zhu, Yongqi Xia, Chuan Lv   +3 more
wiley   +1 more source

Assessment of ventilation heterogeneity in severe asthma using phase‐resolved functional lung magnetic resonance imaging

Physiological Reports, Volume 13, Issue 12, June 2025.
Graphical abstract showing some of the PREFUL‐derived ventilation biomarkers used in this study (left panel) and their response to bronchodilator therapy (top right panel) as well as correlations with FEV1 (bottom right panel). FEV1, forced expiratory volume in 1 s; HV, healthy volunteer; IQD, interquartile distance; PostBD, post‐bronchodilator; PreBD,
Chuan T. Foo, David Langton, Graham M. Donovan, Bruce R. Thompson, Peter B. Noble, Francis Thien   +5 more
wiley   +1 more source

Bronchiectasis after bronchial thermoplasty [PDF]

Journal of Thoracic Disease, 2018
Bronchial thermoplasty (BT) is used in the treatment of severe refractory asthma. It has been found to be beneficial to long-term improvements in the rate of asthma exacerbation, quality of life questionnaire answers (AQLQ), hospitalization, and emergency room visits.
Minzhi, Qiu, Zhengdao, Lai, Shushan, Wei, Qian, Jiang, Jiaxing, Xie, Rihuang, Qiu, Zhiqiang, Wang, Changhao, Zhong, Yu, Chen, Qingling, Zhang, Shiyue, Li, Nanshan, Zhong   +11 more
openaire   +2 more sources

Obesity: Next game changer of allergic airway diseases?

Clinical and Translational Medicine, Volume 15, Issue 5, May 2025.
Obesity affects various aspects of allergic airway diseases, including prevalence, endotypes, clinical features and therapeutic efficacy. Therefore, obesity‐related allergic airway diseases represent a unique class of endotypes and phenotypes, which need much more in‐depth research for tailored treatment.
Wenlong Li, Noah Marx, Qintai Yang, Deyu Fang, Yana Zhang   +4 more
wiley   +1 more source

Recent Developments In Bronchial Thermoplasty For Severe Asthma

Journal of Asthma and Allergy, 2019
Neil C Thomson Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UKCorrespondence: Neil C ThomsonInstitute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow G12 OYN, UKTel +44-141-211-1673Email ...
Thomson NC
doaj  

Quantifying Spatial Distribution of Ventilation Defects in Multiple Pulmonary Diseases With Hyperpolarized 129Xenon MRI

Journal of Magnetic Resonance Imaging, Volume 61, Issue 4, Page 1860-1873, April 2025.
Background Hyperpolarized 129Xe MRI assesses lung ventilation, often using the ventilation defect percentage (VDP). Unlike VDP, defect distribution index (DDI) quantifies spatial clustering of defects. Purpose To quantify spatial distribution of 129Xe ventilation defects using DDI across pulmonary diseases. Study Type Retrospective.
Abdullah S. Bdaiwi, Matthew M. Willmering, Jason C. Woods, Laura L. Walkup, Zackary I. Cleveland   +4 more
wiley   +1 more source