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DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target [PDF]

open access: yesEpigenetics
This study aims to discover drug targeted genes and explore the potential epigenetics mechanisms in bronchiectasis. Cis-expression quantitative trait locus (eQTL) was obtained as exposure, and bronchiectasis from the FinnGen cohort was used as outcome ...
Jiangyue Qin   +7 more
doaj   +2 more sources

Patient attitudes to nebulised antibiotics in the treatment of bronchiectasis: a mixed-methods study

open access: yesERJ Open Research, 2023
Background Regular daily nebulised antibiotics are widely used in managing bronchiectasis. This patient population typically has severe bronchiectasis requiring multiple other medications.
John Davison   +10 more
doaj   +1 more source

‘Teach me how to look after myself’: What people with bronchiectasis want from education in a pulmonary rehabilitation setting

open access: yesThe Clinical Respiratory Journal, 2023
Introduction Pulmonary rehabilitation is recommended for people with bronchiectasis. Various education topics are included in these programmes, but the content is largely guided by the needs of people with other respiratory conditions.
Annemarie L. Lee   +12 more
doaj   +1 more source

Prevalence of asymptomatic bronchiectasis and associations among the health screening population in South Korea

open access: yesERJ Open Research, 2021
Despite the burden of bronchiectasis, there is little data from South Korea regarding asymptomatic bronchiectasis. We aimed to investigate the prevalence of bronchiectasis based on computed tomography (CT) findings, with emphasis on asymptomatic ...
Soo Han Kim   +5 more
doaj   +1 more source

Bronchiectasis as co morbidity with COPD or ILD: complex interactions and severe consequences

open access: yesThe Egyptian Journal of Bronchology, 2023
Background Bronchiectasis is a chronic pulmonary disease characterized by widened, malformed bronchi, with profuse expectoration and impaired quality of life. COPD and ILD are common co-morbidities with bronchiectasis. Methods The present study evaluated
Manal SH. Elhussini   +3 more
doaj   +1 more source

South African Thoracic Society position statement on the management of non-cystic fibrosis bronchiectasis in adults: 2023

open access: yesAfrican Journal of Thoracic and Critical Care Medicine, 2023
Background. Bronchiectasis is a chronic lung disorder that affects the lives of many South Africans. Post-tuberculosis (TB) bronchiectasis is an important complication of previous pulmonary TB and a common cause of bronchiectasis in South Africa (SA). No
A Goolam-Mahomed   +8 more
doaj   +1 more source

Chronic Obstructive Pulmonary Disease Is Associated With Decreased Quality of Life in Bronchiectasis Patients: Findings From the KMBARC Registry

open access: yesFrontiers in Medicine, 2021
Most studies have evaluated the impact of non-cystic fibrosis bronchiectasis (hereafter referred to as bronchiectasis) on quality of life (QoL) in patients with chronic obstructive pulmonary disease (COPD) using COPD cohorts.
Sang Hyuk Kim   +8 more
doaj   +1 more source

Clinical features of patients with asthma, bronchiectasis, and combination of both conditions

open access: yesIndian Journal of Respiratory Care, 2021
Background: Asthma and bronchiectasis are critical diseases for public health. In some patients, asthma and bronchiectasis exist together, and bronchiectasis negatively affects asthma control.
Fatih Uzer, Zehra Boztepe, Aykut Cilli
doaj   +1 more source

The clinical and functional characteristics of bronchiectasis among tuberculosis patients in Upper Egypt: a single-center study

open access: yesThe Egyptian Journal of Bronchology, 2022
Background Tuberculosis (TB) is considered one of the most common causes of bronchiectasis. Bronchiectasis increases clinical and financial burden of patients with TB.
Maiada K. Hashem   +3 more
doaj   +1 more source

Non-antimicrobial airway management of non-cystic fibrosis bronchiectasis

open access: yesJournal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2018
Bronchiectasis are often encountered in clinical practice, and are characterized by abnormal airway dilatation and distortion associated with impaired mucociliary clearance and mucous plugging, which are frequently associated with recurrent infections ...
Ashley M. Egan   +2 more
doaj   +1 more source

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