Results 51 to 60 of about 79,415 (247)

The EMBARC European Bronchiectasis Registry:protocol for an international observational study [PDF]

, 2015
Bronchiectasis is one of the most neglected diseases in respiratory medicine. There are no approved therapies and few large-scale, representative epidemiological studies.
Aksamit, Timothy, Aliberti, Stefano, Blasi, Francesco, Boersma, Wim, Botnaru, Victor, Chalmers, James D., Clifton, Ian, Crichton, Megan, De Soyza, Anthony, Dimakou, Katerina, Elborn, J. Stuart, Gerada, Eleanor, Goeminne, Pieter, Haworth, Charles, Hill, Adam T., Loebinger, Michael, Masefield, Sarah, Menendez, Rosario, Milenkovic, Branislava, Morgan, Lucy, Murris-Espin, Marlene, Neves, Joao, O'Donnell, Anne, Paggiaro, Perluigi, Polverino, Eva, Rademacher, Jessica, Ringshausen, Felix, Rohde, Gernot, Shteinberg, Michal, Skrgat, Sabina, Torres, Antoni, Tramma, Leandro, van der Eerden, Menno, Vendrell, Montserrat, Welte, Tobias, Wilson, Robert   +35 more
core   +9 more sources

Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning

Advanced Intelligent Systems, EarlyView.
A fundamental mucus cleaning mechanism is reported, which utilizes both artificial cilia mechanical sweeping and suction‐based mucus cleaning. A novel haptic feedback interface for the artificial cilia provides touch feedback on tissue contact, enhancing operator control and safety.
Zhongming Lyu, Yusheng Wang, Ruijian Ge, Darren Wang, Matthew Bacchetta, Caitlin T. Demarest, Fabien Maldonado, Xiaoguang Dong   +7 more
wiley   +1 more source

DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target

Epigenetics
This study aims to discover drug targeted genes and explore the potential epigenetics mechanisms in bronchiectasis. Cis-expression quantitative trait locus (eQTL) was obtained as exposure, and bronchiectasis from the FinnGen cohort was used as outcome ...
Jiangyue Qin, Bi Ran, Lian Liu, Ping Li, Zhenni Chen, Diandian Li, Yongchun Shen, Fuqiang Wen   +7 more
doaj   +1 more source

Research priorities in bronchiectasis:a consensus statement from the EMBARC Clinical Research Collaboration [PDF]

, 2016
Bronchiectasis is a disease of renewed interest in light of an increase in prevalence and increasing burden on international healthcare systems. There are no licensed therapies, and large gaps in knowledge in terms of epidemiology, pathophysiology and ...
Anthony De Soyza, Bonaiti, Eva Polverino, Felix C. Ringshausen, Finch, Hester, James D. Chalmers, Langton Hewer, Lee, Michael R. Loebinger, Montserrat Vendrell, Murphy, Pippa Powell, Rosario Menendez, Sarah Masefield, Stefano Aliberti   +15 more
core   +2 more sources

Silicosis, Sarcoidosis, and Silicosarcoidosis Are Overlapping Diagnoses and Difficult to Differentiate

American Journal of Industrial Medicine, EarlyView.
ABSTRACT We evaluated 12 workers with documented exposure to respirable crystalline silica who were referred to a tertiary care center due to clinical suspicion of silicosis, sarcoidosis, or silicosarcoidosis. Although silica exposure is a well‐established risk factor for silicosis and has been associated with autoimmune diseases, mycobacterial ...
Guilherme Ward Leite, Eduardo Kaiser Ururahy Nunes Fonseca, Rodrigo Caruso Chate, Lavinia Clara Del Roio, Sofia de Paiva Memento Machado, Jefferson Benedito de Freitas, Ronaldo Adib Kairalla, Mário Terra‐Filho, Ubiratan Paula Santos, Rafael Futoshi Mizutani   +9 more
wiley   +1 more source

The Efficacy of Therapeutic Respiratory Muscle Training Interventions in People with Bronchiectasis: A Systematic Review and Meta-Analysis [PDF]

, 2020
Background: Respiratory muscle dysfunction is an important health problem with high morbidity and mortality and associated costs in patients with bronchiectasis (BC).
Casuso-Holgado, Maria Jesus, de-la-Casa-Almeida, Maria, Jimenez Cebrian, Ana Maria, Martín Valero, Rocio, Moral Muñoz, José Antonio, Rodríguez Huguet, Manuel   +5 more
core   +3 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Medical Causes of Hospitalisation among Patients with Bronchiectasis: A Nationwide Study in Japan

Pathogens
Purpose: Although the international guidelines for managing bronchiectasis are centred on preventing the exacerbation of bronchiectasis, the medical causes of admissions to hospital among patients with bronchiectasis have not been fully investigated ...
Akihiko Hagiwara, Hisayuki Shuto, Ryohei Kudoh, Shota Omori, Kazufumi Hiramatsu, Jun-ichi Kadota, Kiyohide Fushimi, Kosaku Komiya   +7 more
doaj   +1 more source

Gastro-oesophageal reflux disease increases healthcare use and medical costs in patients with bronchiectasis: a Korean nationwide population-based study

Therapeutic Advances in Gastroenterology, 2021
Background: Gastro-oesophageal reflux disease (GORD) is not only a common aetiology but also accompanying comorbidity of non-cystic fibrosis bronchiectasis (bronchiectasis).
Jai Hoon Yoon, Sang Hyuk Kim, Jiin Ryu, Sung Jun Chung, Youlim Kim, Chang Ki Yoon, Seung Won Ra, Yeon Mok Oh, Hayoung Choi, Hyun Lee   +9 more
doaj   +1 more source

Idiopathic pulmonary fibrosis: evaluation of progression and prognosis after the ATS/ERS/JRS/ALAT statement 2011 [PDF]

, 2012
Objectives The prediction of usual interstitial pneumonia (UIP) progression and prognosis by the a application of HRCT criteria pattern recommended by ATS/ERS/JALAT guidelines 2011 Materials and methods Two radiologists after assessing the baseline HRCT ...
ROMEI, CHIARA
core