VEGF serum concentration and irreversible bronchoconstriction in adult asthmatics.
Advances in Clinical and Experimental Medicine, 2019 BACKGROUND Vascular endothelial growth factor (VEGF) is an angiogenic, heparin-binding glycoprotein playing an important role in the pathogenesis of many diseases and disorders, including asthma.
Krzysztof Gomułka +3 more
semanticscholar +1 more source
Bronchospasm and its biophysical basis in airway smooth muscle
Respiratory Research, 2004 Airways hyperresponsiveness is a cardinal feature of asthma but remains unexplained. In asthma, the airway smooth muscle cell is the key end-effector of bronchospasm and acute airway narrowing, but in just the past five years our understanding of the ...
Fredberg Jeffrey J
doaj +1 more source
Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes [PDF]
, 2013 This article is made available through the Brunel Open Access Publishing Fund and is distributed by the Creative Commons CC-BY 3.0 license, under which all are free to reuse or distribute the article under the condition that this original publication ...
Anderson, SD +5 more
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Effects of Inhaled Brevetoxins in Allergic Airways: Toxin–Allergen Interactions and Pharmacologic Intervention [PDF]
, 2005 During a Florida red tide, brevetoxins produced by the dinoflagellate Karenia brevis become aerosolized and cause airway symptoms in humans, especially in those with pre-existing airway disease (e.g., asthma).
Andrea J. Bourdelais +7 more
core +2 more sources
Leukotriene C4-Synthesis Deficiency
Pediatric Neurology Briefs, 1998 A leukotriene C4-synthesis deficiency, a new inborn error of eicosanoid metabolism characterized by hypotonia, microcephaly, failure to thrive, and retarded development, is described in an infant who died aged 6 months after a rapidly progressive course ...
J Gordon Millichap
doaj +1 more source
The Aftermath of Bronchoconstriction [PDF]
Journal of Engineering and Science in Medical Diagnostics and Therapy, 2019 Asthma is characterized by chronic airway inflammation, airway remodeling, and excessive constriction of the airway. Detailed investigation exploring inflammation and the role of immune cells has revealed a variety of possible mechanisms by which chronic inflammation drives asthma development.
Michael J, O'Sullivan, Bo, Lan
openaire +2 more sources
Linking ventilation heterogeneity quantified via hyperpolarized He-3 MRI to dynamic lung mechanics and airway hyperresponsiveness [PDF]
, 2015 Advancements in hyperpolarized helium-3 MRI (HP 3He-MRI) have introduced the ability to render and quantify ventilation patterns throughout the anatomic regions of the lung. The goal of this study was to establish how ventilation heterogeneity relates to
Albert, Mitchell S. +3 more
core +10 more sources
Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways [PDF]
, 2018 The mechanisms of controlling airway smooth muscle (ASM) tone are of utmost clinical importance as inappropriate constriction is a hallmark in asthma and chronic obstructive pulmonary disease.
Hollenhorst, M. I. +7 more
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Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]
, 2014 The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard +4 more
core +4 more sources
Sports Medicine, 2016 In athletes, a secure diagnos is of exercise-induced bronchoconstriction (EIB) is dependent on objective testing. Evaluating spirometric indices of airflow before and following an exercise bout is intuitively the optimal means for the diagnosis; however,
J. Hull +4 more
semanticscholar +1 more source