Results 101 to 110 of about 62,270 (271)

Management of Asthma and COPD Exacerbations in Adults in the ICUKey PointsClinical QuestionClinical Question

CHEST Critical Care
Severe, life-threatening asthma and COPD exacerbations are managed commonly in the ICU and are associated with significant morbidity and mortality. It is important to understand the commonalities and differences in the diagnosis and management of these ...
Stephen A. Mein, MD, Michael C. Ferrera, MD   +1 more
doaj   +1 more source

Treatment of COPD with Long-Acting Bronchodilators: Association Between Early and Longer-Term Clinically Important Improvement

International Journal of COPD, 2021
Claus F Vogelmeier,1 Ian P Naya,2,3 François Maltais,4 Leif Bjermer,5 Edward M Kerwin,6 Lee Tombs,7 Paul W Jones,2 Chris Compton,2 David A Lipson,8,9 Isabelle H Boucot2,10 1Department of Medicine, Pulmonary and Critical Care Medicine, University ...
Vogelmeier CF, Naya IP, Maltais F, Bjermer L, Kerwin EM, Tombs L, Jones PW, Compton C, Lipson DA, Boucot IH   +9 more
doaj  

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

Allergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco, Evelina Fagone, Raffaele Campisi, Andrea Portacci, Giulia Scioscia, Corrado Pelaia, Angelantonio Maglio, Claudio Candia, Vitaliano Nicola Quaranta, Isabella Carrieri, Alessandro Saglia, Alessandro Vatrella, Girolamo Pelaia, Carlo Vancheri, Maria Pia Foschino Barbaro, Maria D'Amato, Giovanna Elisiana Carpagnano, Nunzio Crimi, Claudia Crimi, on behalf of the Southern Italy Network on Severe Asthma Therapy, Rossella Intravaia, Morena Porto, Pietro Impellizzeri, Maria Provvidenza Pistorio, Fabio Vignera, Andrea Alessia Nardo, Concetta Giannì, Silvano Dragonieri, Flogerta Sana, Valeria Pezzuto, Santina Ferulli, Massimo Triggiani, Roberta Parente, Pasquale Tondo, Piera Soccio, Donato Lacedonia, Luigi Ciampo, Antonio Franzese, Valeria Longobardi   +38 more
wiley   +1 more source

The Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide 400 μg Administered by Inhalation as Single and Multiple (Twice Daily) Doses in Healthy Chinese Participants

International Journal of COPD, 2023
Weimin Li,1 Sami Z Daoud,2 Roopa Trivedi,3 Pradeep B Lukka,4 Eulalia Jimenez,5 Eduard Molins,5 Catherine Stewart,6 Pranob Bharali,3,7 Esther Garcia-Gil8 1Clinical Trial Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, People ...
Li W, Daoud SZ, Trivedi R, Lukka PB, Jimenez E, Molins E, Stewart C, Bharali P, Garcia-Gil E   +8 more
doaj  

Optimization of Bronchodilator Treatment in COPD: A Comparison of the Glycopyrrolate/Formoterol Combination vs. Formoterol Alone [PDF]

Kirkuk Journal of Medical Sciences
Background: Using a glycopyrrolate/formoterol combination to manage COPD patients is considered a new method. The objectives of this study are to evaluate the effectiveness of the glycopyrrolate/formoterol combination against formoterol alone in ...
Hiwa Saber, Ahmed Abdullah
doaj   +1 more source

The Nasal Microbiome and Associations With Environmental Exposures and Respiratory Health

Allergy, EarlyView.
This study evaluates the association of the nasal microbiome with air pollutants, meteorological conditions, and respiratory health in adolescents. Bacterial diversity is positively associated with hay fever and short‐term NO2 exposure, and negatively with temperature. A Moraxella‐dominated nasotype is linked to lower O3 exposure and higher temperature
Javier Perez‐Garcia, Anne K. Bozack, Sheryl L. Rifas‐Shiman, Yanjiao Zhou, Joanne Sordillo, Brent Coull, Heike Luttmann‐Gibson, Joel Schwartz, Marie‐France Hivert, Emily Oken, Diane R. Gold, Andres Cardenas   +11 more
wiley   +1 more source

Bronchodilator testing: an endless story [PDF]

, 2010
Raffaello Pellegrino, Andrea Antonelli, Michele Mondino   +2 more
openalex   +1 more source

Protective Role for Itaconate During Inhaled Allergen Challenge

Allergy, EarlyView.
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers, Patricia P. Ogger, Christina Michalaki, Helen Stölting, Simone A. Walker, Anna Caldwell, John M. Halket, Kathryn Duvall, Atia Batool, Lisha Joshi, Helen O'Brien, Cormac McCarthy, Timothy Hinks, Gail M. Gauvreau, Paul M. O'Byrne, Clare M. Lloyd, Adam J. Byrne   +16 more
wiley   +1 more source

Imidafenacin, An Orally Active Muscarinic Receptor Antagonist, Improves Pulmonary Function In Patients With Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled 3×3 Crossover Phase II Trial

International Journal of COPD, 2019
Kentaro Machida,1,* Tomotaka Kawayama,2,* Masaharu Kinoshita,3,* Masakazu Ichinose,4 Tohru Tsuda,5 Shohei Takata,6 Hiroshi Koto,7 Makoto Yoshida,8 Yoshinori Ashihara,9 Masaru Kawashima,10 Hideaki Suna,10 Hiromasa Inoue1 1Department of Pulmonary Medicine,
Machida K, Kawayama T, Kinoshita M, Ichinose M, Tsuda T, Takata S, Koto H, Yoshida M, Ashihara Y, Kawashima M, Suna H, Inoue H   +11 more
doaj  

Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli [PDF]

, 2006
C. Liu
openalex   +1 more source