Results 11 to 20 of about 61,454 (303)
Spirometry and Bronchodilator Test
Spirometry is a physiological test for assessing the functional aspect of the lungs using an objective indicator to measure the maximum amount of air that a patient can inhale and exhale. Acceptable spirometry testing needs to be conducted three times by an acceptable and reproducible method for determining forced vital capacity (FVC).
Yun Su Sim +9 more
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Purpose Randomized trials report that single-inhaler triple therapy is more effective than dual bronchodilators at reducing exacerbations in patients with chronic obstructive pulmonary disease (COPD).
S. Suissa, S. Dell'aniello, P. Ernst
semanticscholar +1 more source
COPD: maximization of bronchodilation [PDF]
The most recent guidelines define COPD in a multidimensional way, nevertheless the diagnosis is still linked to the limitation of airflow, usually measured by the reduction in the FEV1/FVC ratio below 70%. However, the severity of obstruction is not directly correlated to symptoms or to invalidity determined by COPD.
Stefano Nardini +9 more
openaire +7 more sources
Background: Asthma can have a negative impact on the productivity of paid and unpaid individuals. In this study, we aimed to investigate the impact of salmeterol, which, in recent years, has become available for the treatment of asthma in Japan, on the ...
Takehiko Miyagawa, Shuzo Nishimura
doaj +1 more source
Background: The smooth muscle contractions of the tracheobronchial airways are mediated through the balance of adrenergic, cholinergic and peptidergic nervous mechanisms.
Behrang Alani +2 more
doaj +1 more source
Bronchodilator reversibility in asthma and COPD: findings from three large population studies
Bronchodilator response (BDR) testing is used as a diagnostic method in obstructive airway diseases. The aim of this investigation was to compare different methods for measuring BDR in participants with asthma and chronic obstructive pulmonary disease ...
C. Janson +18 more
semanticscholar +1 more source
We performed a meta-analysis to compare the impact of triple combination therapy with inhaled corticosteroids (ICS), long-acting β2-agonists (LABAs) and long-acting muscarinic receptor antagonists (LAMAs) versus LABA/LAMA combination therapy or single ...
M. Cazzola +3 more
semanticscholar +1 more source
Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts
Background: Interleukin (IL)-26 is a neutrophil-mobilizing and bactericidal cytokine that is enhanced in human airways in vivo in response to endotoxin from Gram-negative bacteria.
Karlhans Fru Che +4 more
doaj +1 more source
Clinical significance of the bronchodilator response in children with severe asthma
Our objective was to determine those characteristics associated with reversibility of airflow obstruction and response to maximal bronchodilation in children with severe asthma through the Severe Asthma Research Program (SARP).
A. Coverstone +18 more
semanticscholar +1 more source
Longitudinal FEV1 and Exacerbation Risk in COPD: Quantifying the Association Using Joint Modelling
Kirill Zhudenkov,1 Robert Palmér,2 Alexandra Jauhiainen,3 Gabriel Helmlinger,4,5 Oleg Stepanov,1 Kirill Peskov,1,6 Ulf G Eriksson,2 Ulrika Wählby Hamrén2 1M&S Decisions LLC, Moscow, Russia; 2Clinical Pharmacology & Quantitative
Zhudenkov K +7 more
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