Results 11 to 20 of about 63,990 (275)

Pharmacokinetics and Bioequivalence of Fudosteine in Healthy Chinese Volunteers Under Fasting and Fed Conditions: A 4‐Way Replicate Crossover Study

Clinical Pharmacology in Drug Development, Volume 12, Issue 1, Page 30-37, January 2023., 2023
Abstract The bioequivalence of a generic fudosteine tablet vs a brand‐named fudosteine tablet under fasting and fed conditions was evaluated in this study. This randomized, open‐label, single‐dose, 4‐way replicate, crossover, bioequivalence study included 64 healthy Chinese subjects (fasting cohort, n = 32; fed cohort, n = 32) who were assigned to ...
Mingxue Zhu, Yi Tao, Junliang Pu, Hongtao Zhao, Lei Wan, Peilin Zhang, Chengyong Tang   +6 more
wiley   +1 more source

Tongxinluo enhances the effect of atorvastatin on the treatment of atherosclerosis with chronic obstructive pulmonary disease by maintaining the pulmonary microvascular barrier

Food Science &Nutrition, Volume 11, Issue 1, Page 390-407, January 2023., 2023
COPD aggravates AS, possibly through the destruction of pulmonary microvascular barrier function; thus, lung inflammation triggers systemic inflammation. In treating COPD with AS, TXL enhances the antiatherosclerotic effect of Ato, protecting the pulmonary microvascular barrier.
Xiangnan Kuang, Yafen Wang, Shiqiao Liu, Liping Chang, Yujie Yin, Zhen Li, Yi Liu, Wenyan Li, Yunlong Hou, Hongtao Wang, Junqing Liang, Zhenhua Jia   +11 more
wiley   +1 more source

Is slide‐based or video‐based eLearning better at achieving behavioural change in bronchiolitis management? A cluster‐based randomised control trial

Journal of Paediatrics and Child Health, Volume 58, Issue 12, Page 2177-2182, December 2022., 2022
Aim This cluster‐based randomised control trial examines the comparative efficacy of two eLearning programs that teach clinicians evidence‐based bronchiolitis management for children less than 12 months of age. Methods Six hospitals, matched for size, were randomly allocated to either video‐based (arm A) or slide‐based (arm B) eLearning programs.
Rutty Talati, Bob Fonseca, Kylie‐ann Mallitt, John Mackenzie   +3 more
wiley   +1 more source

Paediatrics: how to manage acute asthma exacerbations

Drugs in Context, 2021
Background: Asthma is the most common chronic disease of childhood and a major source of childhood health burden worldwide. These burdens are particularly marked when children experience characteristic ‘symptom flare-ups’ or acute asthma exacerbations ...
James S Leung
doaj   +1 more source

Assessing the clinical value of fast onset and sustained duration of action of long-acting bronchodilators for COPD [PDF]

, 2015
Date of Aceptance: 12/02/2015 Acknowledgments The authors were assisted in the preparation of the manuscript by Sarah Filcek, a professional medical writer at CircleScience (Tytherington, UK), part of KnowledgePoint360, an Ashfield Company.
Beeh, Kai M, Cazzola, Mario, Price, David, Roche, Nicolas   +3 more
core   +1 more source

Serum magnesium levels and its correlation with level of control in patients with asthma: A hospital-based, cross-sectional, prospective study

Lung India, 2018
Context: Magnesium (Mg) is an intracellular cation which takes part in various functions including smooth muscle contractility. Studies have shown that serum Mg level has no significant effect on asthma severity.
Vasudev Malik Daliparty, Mohan K Manu, Aswini Kumar Mohapatra   +2 more
doaj   +1 more source

Caffeine for asthma [PDF]

, 2010
Background Caffeine has a variety of pharmacological effects; it is a weak bronchodilator and it also reduces respiratory muscle fatigue. It is chemically related to the drug theophylline which is used to treat asthma.
Becker, Bruce, Bukowskyj, Cheney, Colacone, Crivelli, Curatolo, Duffy, Gong, Grollman, Henderson, Kivity, Pagano, Robertson, Simmons, Stephenson, Taylor, Taylor, Woodcock, Yurach   +19 more
core   +1 more source

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]

, 2014
The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard, Kaplan, Alan, Price, David, Román-Rodríguez, Miguel, van der Molen, Thys   +4 more
core   +10 more sources

Anticholinergic therapy for acute asthma in children. [PDF]

, 2012
Inhaled anticholinergics as single agent bronchodilators (or in combination with beta(2)-agonists) are one of the several medications available for the treatment of acute asthma in ...
Beakes, Beck, Benito Fernandez, Bever, Bratteby, British Thoracic Society, Brown, Browne, Calvo, Cook, Craven, Cugell, DeStefano, Ducharme, Everard, Goggin, Gross, Guill, Hayday, Iramain, Lew, Lin, Lung, Mallol, McDonald, Mirsadraee, National Asthma Council Australia, Ni, Plotnick, Pulejo, Quereshi, Qureshi, Rayner, Reisman, Rodrigo, Schuh, Sienra Monge, Storms, Storr, Tal, Timsit, Ulrik, Undem, Wade, Ward, Ward, Yeung, Youngchaiyud, Zimmerman, Zorc   +49 more
core   +2 more sources

Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease [PDF]

, 2013
The aim of the study was to characterize pharmacokinetics of tiotropium solution 5 µg compared to powder 18 µg and assess dose-dependency of tiotropium solution pharmacodynamics in comparison to placebo.
Cornelissen, PJG, Derom, Eric, Disse, B, Hohlfeld, JM, Peterkin, V, Sharma, A, Towse, L, van Noord, JA   +7 more
core   +1 more source