Overprescription of short-acting β2 agonists: reflections from the SABINA study in Brazil
Objective: To assess prescription patterns for short-acting b2 agonists (SABAs) and other asthma medications in asthma patients treated by specialists and participating in the SABA use IN Asthma (SABINA) study in Brazil.
Martti Anton Antila+7 more
doaj +2 more sources
Adherence to Inhalation Devices in Patients with Chronic Obstructive Pulmonary Disease
Luis Fernando Valladales-Restrepo,1– 3 María Camila Oyuela-Gutiérrez,3 Ana Camila Delgado-Araujo,1 Juliana Calvo-Salazar,1 Daniel Osorio-Bustamante,3 Cesar Eduardo Lerma-Barco,3 Jorge Enrique Machado-Alba1 1Grupo de Investigación en Farmacoepidemiología ...
Valladales-Restrepo LF+6 more
doaj
Calcium and potassium channels are involved in curcumin relaxant effect on tracheal smooth muscles
Context Curcumin, the active component of Curcuma longa L. (Zingiberaceae), exhibits a wide variety of biological activities including vasodilation and anti-inflammation.
Bahman Emami+7 more
doaj +1 more source
Fact-based Agent modeling for Multi-Agent Reinforcement Learning [PDF]
In multi-agent systems, agents need to interact and collaborate with other agents in environments. Agent modeling is crucial to facilitate agent interactions and make adaptive cooperation strategies. However, it is challenging for agents to model the beliefs, behaviors, and intentions of other agents in non-stationary environment where all agent ...
arxiv
Manuel Enrique Machado-Duque,1,2 Andrés Gaviria-Mendoza,1,2 Luis Fernando Valladales-Restrepo,1,2 Andrés González-Rangel,3 Maria Eugenia Laucho-Contreras,3,4 Jorge Enrique Machado-Alba1 1Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia,
Machado-Duque ME+5 more
doaj
Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease (Review) [PDF]
Background The long-acting bronchodilator tiotropium and single inhaler combination therapy of inhaled corticosteroids and long-acting beta(2)-agonists are both commonly used for maintenance treatment of chronic obstructive pulmonary disease.
Appleton+10 more
core +1 more source
Short-acting β2-agonist prescriptions in patients with asthma: findings from the South Korean cohort of SABINA III [PDF]
Background/Aims Despite short-acting β2-agonist (SABA) overuse being associated with poor asthma outcomes, data on SABA use in South Korea is scarce.
Kwang-Ha Yoo+6 more
doaj +1 more source
Efficacy of tiotropium-olodaterol fixed-dose combination in COPD [PDF]
Tiotropium-olodaterol, formulated in the Respimat soft-mist inhaler, is an inhaled fixed-dose combination (FDC) of a long-acting muscarinic antagonist (LAMA) and a long-acting beta(2)-agonist (LABA), commercialized under the name of Spiolto or Stiolto ...
Brusselle, Guy, Derom, Eric, Joos, Guy
core +1 more source
Linking guideline‐directed medical therapy (GDMT) implementation and appropriate polypharmacy management in heart failure (HF). Polypharmacy can represent a barrier to the proper implementation of life‐prolonging GDMT for HF. A reasonable balance between the optimization of GDMT and avoiding inappropriate polypharmacy is mandatory in the contemporary ...
Davide Stolfo+27 more
wiley +1 more source
Risk factors for COPD exacerbations in inhaled medication users: the COPDGene study biannual longitudinal follow-up prospective cohort. [PDF]
BackgroundDespite inhaled medications that decrease exacerbation risk, some COPD patients experience frequent exacerbations. We determined prospective risk factors for exacerbations among subjects in the COPDGene Study taking inhaled medications ...
,+8 more
core +4 more sources