Results 121 to 130 of about 157,032 (265)

Comprehensive Phytochemical Profiling and Multi‐Target Biological Evaluation of Hibiscus sabdariffa L. Calyx Extracts From Libya: A Promising Functional Food Candidate With Antibacterial, Antioxidant, Anti‐Inflammatory, and Cytotoxic Properties: Validation Through In Silico Approaches

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study presents a comprehensive evaluation of Hibiscus sabdariffa L. calyx extracts from Libya, integrating phytochemical profiling, multi‐target biological activities, and in silico validation. Aqueous and ethanolic extracts were prepared and assessed for antibacterial activity against multidrug‐resistant clinical isolates (MIC: 6.25–25 mg/mL; MBC/
Ahmed Saeed Kabbashi, Zuhir S. Mussa Akrim, Mohammed B. Suliman, Sanadelaslam S. A. El‐Hddad, Ahmed Ali Mustafa, Maryam Mohammed Ibrahim, Esraa Radwan Ibrahim, Mona Rafea Mosa, Rama Burhan Hasan   +8 more
wiley   +1 more source

A Straightforward Synthesis of a Diene From a Homoallylic Bromide to Access Cycloadducts to Elucidate Michael Acceptors as Antimicrobial Motifs

ChemistrySelect, Volume 11, Issue 25, 3 July 2026.
A straightforward method to cleanly yield a novel diene from isopulegol was developed. The diene served as a precursor to various cycloadducts, which led to the identification of Michael acceptors as antimicrobial motifs. ABSTRACT Conjugated dienes are useful precursors to cascade reactions that undergo cycloadditions to access polycyclic compounds ...
Jose G. Urbiola, Caroline Laughlin‐Black, Jace Salgado, Kaitlyn Varela, Hadi D. Arman, Catherine A. Wakeman, Francis K. Yoshimoto   +6 more
wiley   +1 more source

Establishing the Epidemiological Cut‐Off Value (ECOFF) for Cefquinome Against Staphylococcus aureus Using Standardised MIC Data

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
A total of 110 Staphylococcus aureus isolates from cattle were analysed to determine the epidemiological cut‐off value (ECOFF) for cefquinome. Minimum inhibitory concentrations (MICs) were determined using standardised agar dilution and broth microdilution methods following 24 h incubation.
Ijaz Ahmad, Shakoor Ahmed, Muhammad Faizan, Shahab Ahmad Nawaz, Shabana Naz, Muhammad Israr, Rifat Ullah Khan, Antonella Perillo, Huda A. Alqahtani   +8 more
wiley   +1 more source

Assessment of Ocular Surface Pathogen Susceptibility to Ultraviolet‐C (UVC) Light Treatment With a Novel Prototype Device—An In Vitro Study

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Purpose Assess in vitro efficacy of a device emitting 265 nm UVC light against bacteria isolated from veterinary infectious keratitis. Methods Twenty‐seven clinically‐derived bacterial isolates: Staphylococcus pseudintermedius (n = 10; including n = 2 methicillin‐resistant Staphylococcus pseudintermedius [MRSP]), Staphylococcus aureus (n = 1),
Oliver Joe Williams, Charlotte Dawson, Maria‐Christine Fischer, Siân‐Marie Frosini   +3 more
wiley   +1 more source

Antibacterial Activity of Heteropolytungstates Against Proteus mirabilis

European Journal of Inorganic Chemistry, Volume 29, Issue 18, 22 June 2026.
We investigated the in vitro antibacterial activity of several heteropolytungstates against P. mirabilis, a drug‐resistant pathogen. All tested polyanions inhibited bacterial growth, with the Preyssler–Pope–Jeannin polyanion P5W30 exhibiting the highest activity (MIC = 0.78 mg/mL).
Nour El Ghouch, Ahmad Asaad, Rana El Hajj, Sahar Khandan, Matthias S. Ullrich, Ulrich Kortz   +5 more
wiley   +1 more source

Targeting of Staphyloxanthin and α‐Hemolysin by Natural Compound L‐Malic Acid Suppresses Staphylococcus aureus Virulence

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
L‐malic acid, a natural TCA cycle intermediate, attenuates the virulence of Staphylococcus aureus through dual metabolic and regulatory mechanisms. It redirects central carbon flux away from the mevalonate pathway and inhibits the key enzyme CrtO, suppressing staphyloxanthin biosynthesis and impairing bacterial resistance to oxidative stress ...
Li Shen, Bingjie Wang, Jinjin Yang, Xinru Yuan, Zhixuan Chen, Can Yang, Jiana Fu, Haojin Gao, Weihua Han, Junhong Shi, Fangyou Yu, Jingyi Yu   +11 more
wiley   +1 more source

Evaluation of gradient diffusion in vitro susceptibility testing of Aerococcus urinae

Journal of Global Antimicrobial Resistance
Objective: Aerococcus urinae antimicrobial susceptibility testing can be performed via broth microdilution with Mueller-Hinton broth supplemented with lysed horse blood. We sought to compare this with the commonly used gradient diffusion method. Methods:
Kendall Kling, Adil Menon, Paige Norconk, David Zhu, Teresa Zembower, Chao Qi   +5 more
doaj   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Thymol Chemotype Thymus vulgaris L. Hydrolate: Volatile Chemical Fraction Composition and Antimicrobial Activity Against Bacterial and Fungal Pathogens

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Phytochemistry and bioactivity of thymol chemotype Thymus vulgaris L. hydrolate. ABSTRACT The increasing prevalence of antimicrobial resistance necessitates the development of alternative antimicrobial agents derived from natural sources. This study evaluated the volatile chemical profile and antimicrobial activity of a thymol‐containing hydrolate ...
Stefania Garzoli, Joel Horacio Elizondo‐Luevano, Anis Ben Hsouna, Rania Ben Saad, Miroslava Kačániová   +4 more
wiley   +1 more source

Valorization of Raspberry (Rubus Idaeus L.) Leaves via Ultrasound‐Assisted Extraction and Preparative HPLC Fractionation: Antioxidant Kinetics, Antimicrobial Activity, and Performance in Bulk Oils and Pickering Emulsions

eFood, Volume 7, Issue 3, June 2026.
ABSTRACT Raspberry (Rubus idaeus L.) leaves are an abundant agri‐food by‐product with high potential as a source of natural bioactive compounds. In this study, ultrasound‐assisted extraction (UAE) was applied as a green approach to recover phenolic‐rich extracts, which were subsequently characterized by HPLC–DAD and high‐resolution mass spectrometry ...
Sara Bolchini, Parham Joolaei Ahranjani, Maria Concetta Tenuta, Sabrina Vorderegger, Sissy Häsler Gunnarsdottir, Anja Schuster, Giovanna Ferrentino   +6 more
wiley   +1 more source