Results 51 to 60 of about 42,661 (228)

Comparative Evaluation of Disc Diffusion and E-test with Broth Micro-dilution in Susceptibility testing of Amphotericin B, Voriconazole and Caspofungin against Clinical Aspergillus isolates [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Clinical importance of Aspergillus has increased over the past few decades because of rise in immunosuppressive drugs and immune-modulating diseases.
Prashant Gupta, Vineeta Khare, Deepak Kumar, Abrar Ahmad, Gopa Banerjee, Mastan Singh   +5 more
doaj   +1 more source

Discordance of vancomycin minimum inhibitory concentration for methicillin-resistant Staphylococcus aureus at 2 μg/mL between Vitek II, E-test, and Broth Microdilution [PDF]

PeerJ, 2020
Background Vancomycin, the first line antibiotic for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, is often administered inappropriately when MIC is greater than 2 µg/mL, including ‘susceptible’ strains.
Chien-Feng Kuo, Chon Fu Lio, Hsiang-Ting Chen, Yu-Ting Tina Wang, Kevin Sheng-Kai Ma, Yi Ting Chou, Fu-Chieh Chang, Shin-Yi Tsai   +7 more
doaj   +2 more sources

Comparison of Broth Microdilution, Agar Dilution, and Etest for Susceptibility Testing of Doripenem against Gram-Negative and Gram-Positive Pathogens

, 2010
The susceptibility of 513 clinical isolates to doripenem was determined by broth microdilution, agar dilution, and Etest. Overall agreements for Etest and agar dilution MIC values compared to reference broth microdilution at ±1 log 2
R. Flamm, K. Bush, B. Foleno, K. Amsler, C. Santoro   +4 more
core   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Incidence, Risk Factors and Susceptibility Prole of Candida species Isolated from Blood of Non-Neutropenic Medical Intensive Care Unit Patients in a Tertiary Care Centre [PDF]

Journal of Krishna Institute of Medical Sciences University, 2016
Background: The critically ill patients are particularly susceptible to rapid colonization by endemic pathogens or hospital ora. Both immunocompetent and immunocompromised patients are particularly exposed to various risk factors.
Vijaya S. Rajmane, V. C. Patil, Shivaji T. Mohite, M. P. Ghatole   +3 more
doaj  

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Copper oxide nanoparticles: an antidermatophytic agent for Trichophyton spp.

Nanotechnology Reviews, 2015
Copper oxide (CuO) is one of the most important transition metal oxides due to its unique properties. It is used in various technological applications such as high critical temperature, superconductors, gas sensors, in photoconductive applications and so
Kumar Rajesh, Shukla Shashi Kant, Pandey Anand, Srivastava Sanjeev Kumar, Dikshit Anupam   +4 more
doaj   +1 more source

Comparative evaluation of the UMIC Colistine kit to assess MIC of colistin of gram-negative rods

BMC Microbiology, 2019
Background The recent description of the first plasmid-mediated colistin-resistant gene mcr-1, conferring transferable and low-level resistance to colistin, raised concern about the need to implement a rapid and reliable screening method to detect ...
Lucie Bardet, Liliane Okdah, Stéphanie Le Page, Sophie Alexandra Baron, Jean-Marc Rolain   +4 more
doaj   +1 more source

Evaluation of Spectrophotometric Broth Microdilution Method to Determine the Fluconazole MIC of the Candida Species [PDF]

, 2002
Background :Although the broth microdilution method has been recently established for antifungal susceptibility testing of the Candida species, there is still an argue in the interpretation of the trailing endpoint.
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