Lipid Transport in Brown Adipocyte Thermogenesis. [PDF]
Front Physiol, 2021 Non-shivering thermogenesis is an energy demanding process that primarily occurs in brown and beige adipose tissue. Beyond regulating body temperature, these thermogenic adipocytes regulate systemic glucose and lipid homeostasis.
Wade G, McGahee A, Ntambi JM, Simcox J.
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Peroxisome proliferator-activated receptor gamma in white and brown adipocyte regulation and differentiation. [PDF]
Physiol Res, 2020 In as early as 1997, the World Health Organization officially recognized obesity as a chronic disease. The current epidemic of obesity and overweightness has aroused great interest in the study of adipose tissue formation.
Wu H, Li X, Shen C.
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Regulation of white and brown adipocyte differentiation by RhoGAP DLC1. [PDF]
PLoS ONE, 2017 Adipose tissues constitute an important component of metabolism, the dysfunction of which can cause obesity and type II diabetes. Here we show that differentiation of white and brown adipocytes requires Deleted in Liver Cancer 1 (DLC1), a Rho GTPase ...
Choon Kiat Sim +9 more
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Deconstructing cold-induced brown adipocyte neogenesis in mice. [PDF]
Elife, 2022 Cold-exposure triggers neogenesis in classic interscapular brown adipose tissue (BAT) that involves activation of b1-adrenergic receptors, proliferation of PDGFRA+ adipose tissue stromal cells (ASCs), and recruitment of immune cells whose phenotypes are ...
Burl RB +4 more
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The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function [PDF]
Frontiers in Endocrinology, 2023 IntroductionBrown adipocytes produce heat through non shivering thermogenesis (NST). To adapt to temperature cues, they possess a remarkably dynamic metabolism and undergo substantial cellular remodeling.
Zeynep Koçberber +5 more
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Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]
Molecular Metabolism, 2017 Objective: Previous work has suggested that white adipocytes may also show a mammary luminal secretory cell phenotype during lactation. The capacity of brown and beige/brite adipocytes to display a mammary cell phenotype and the levels at which they ...
Li Li +8 more
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Melatonin Regulates Differentiation of Sheep Brown Adipocyte Precursor Cells Via AMP-Activated Protein Kinase [PDF]
Frontiers in Veterinary Science, 2021 In sheep industry, hypothermia caused by insufficient brown adipose tissue (BAT) deposits is one of the major causes of lamb deaths. Enhancing the formation and function of BAT in neonatal lamb increases thermogenesis and hence reduces economic losses ...
Xu-Yang Gao +6 more
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Extracellular calcium modulates brown adipocyte differentiation and identity
Scientific Reports, 2017 Brown adipocytes are important in regulating non-shivering thermogenesis, whole body glucose and lipid homeostasis. Increasing evidence supports an important role of metabolites as well as macro- and micronutrients in brown adipocyte differentiation and ...
Ines Pramme-Steinwachs +2 more
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Collagen-derived dipeptide prolyl-hydroxyproline cooperates with Foxg1 to activate the PGC-1α promoter and induce brown adipocyte-like phenotype in rosiglitazone-treated C3H10T1/2 cells [PDF]
Frontiers in NutritionBackgroundThe global obesity epidemic is a significant public health issue, often leading to metabolic disorders such as diabetes and cardiovascular diseases.
Kaho Nomura +9 more
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A key role for P2RX5 in brown adipocyte differentiation and energy homeostasis [PDF]
AdipocyteBrown adipocytes are defined based on a distinct morphology and genetic signature that includes, amongst others, the expression of the Purinergic 2 Receptor X5 (P2RX5).
Maria Razzoli +10 more
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