The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function [PDF]
Frontiers in Endocrinology, 2023 IntroductionBrown adipocytes produce heat through non shivering thermogenesis (NST). To adapt to temperature cues, they possess a remarkably dynamic metabolism and undergo substantial cellular remodeling.
Zeynep Koçberber +5 more
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Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]
Molecular Metabolism, 2017 Objective: Previous work has suggested that white adipocytes may also show a mammary luminal secretory cell phenotype during lactation. The capacity of brown and beige/brite adipocytes to display a mammary cell phenotype and the levels at which they ...
Li Li +8 more
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Melatonin Regulates Differentiation of Sheep Brown Adipocyte Precursor Cells Via AMP-Activated Protein Kinase [PDF]
Frontiers in Veterinary Science, 2021 In sheep industry, hypothermia caused by insufficient brown adipose tissue (BAT) deposits is one of the major causes of lamb deaths. Enhancing the formation and function of BAT in neonatal lamb increases thermogenesis and hence reduces economic losses ...
Xu-Yang Gao +6 more
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Collagen-derived dipeptide prolyl-hydroxyproline cooperates with Foxg1 to activate the PGC-1α promoter and induce brown adipocyte-like phenotype in rosiglitazone-treated C3H10T1/2 cells [PDF]
Frontiers in NutritionBackgroundThe global obesity epidemic is a significant public health issue, often leading to metabolic disorders such as diabetes and cardiovascular diseases.
Kaho Nomura +9 more
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A key role for P2RX5 in brown adipocyte differentiation and energy homeostasis [PDF]
AdipocyteBrown adipocytes are defined based on a distinct morphology and genetic signature that includes, amongst others, the expression of the Purinergic 2 Receptor X5 (P2RX5).
Maria Razzoli +10 more
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Brown adipocytes of sucrose-overfed rats treated with corticosterone: A stereological and ultrastructural study [PDF]
, 2007 The aim of this study was to examine the effects of short-term corticosterone treatment on brown adipocytes of rats overfed with sucrose. Ultrastructural and stereological analysis showed that brown adipocyte components responded to the applied ...
Maja Cakic-Milosevic +2 more
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Brown Adipose Tissue Heterogeneity, Energy Metabolism, and Beyond
Frontiers in Endocrinology, 2021 Brown adipocyte in brown adipose tissue (BAT) specializes in expending energy through non-shivering thermogenesis, a process that produces heat either by uncoupling protein 1 (UCP1) dependent uncoupling of mitochondrial respiration or by UCP1 independent
Abhijit Babaji Shinde +3 more
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Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat
Nature Communications, 2021 Brown adipocytes contribute to energy balance, and adipocyte development and brown adipocyte thermogenesis are in part regulated by epigenetic modifications.
Fenfen Li +11 more
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Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase. [PDF]
PLoS ONE, 2013 BackgroundBrown adipocytes play an important role in regulating the balance of energy, and as such, there is a strong correlation between obesity and the amount of brown adipose tissue.
Hye-Ryung Choi +8 more
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A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes
Bio-Protocol, 2021 Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha +3 more
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