Results 101 to 110 of about 39,242 (266)
Shades of brown: an introduction for the special focus issue of Adipocyte on “brown and beige/brite adipocytes” [PDF]
Adipocyte, 2016 The re-discovery of brown adipose tissue in humans has re-kindled enormous interest in the research of brown, and its related brown-like adipocytes, i.e., beige or brite adipocytes.
openaire +2 more sources
Food Safety and Health, EarlyView.Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima +4 more
wiley +1 more source
MicroRNA networks regulate development of brown adipocytes [PDF]
Trends in Endocrinology & Metabolism, 2013 Brown adipose tissue (BAT) is specialized for heat generation and energy expenditure as a defense against cold and obesity; in both humans and mice increased amounts of BAT are associated with a lean phenotype and resistance to development of the metabolic syndrome and its complications.
Trajkovski, Mirko, Lodish, Harvey
openaire +5 more sources
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Histone acetylation modulates uncoupling protein1 expression in brown adipocytes [PDF]
, 2014 Uncoupling protein 1 (UCP1) is a classical feature of brown adipocytes and understanding its regulatory mechanism will help in the development of a pharmacological approach for obesity and associated metabolic diseases.
Rajan, Anubama
core +1 more source
Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue
iNew Medicine, EarlyView.ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao +3 more
wiley +1 more source
Scientific Reports, 2017 We previously reported brown adipocytes can proliferate even after differentiation. To test the involvement of mature adipocyte proliferation in cell number control in fat tissue, we generated transgenic (Tg) mice over-expressing cell-cycle inhibitory ...
Yuko Okamatsu-Ogura +8 more
doaj +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen +2 more
wiley +1 more source
Scientific Reports, 2017 The epidemic of obesity and diabetes has markedly spurred the research interest in adipocyte biology. Brown adipocytes are specialized for energy expenditure and of therapeutic interest for treatment of metabolic diseases, but how brown adipocytes are ...
David W. Reid +4 more
doaj +1 more source
Physiologically-induced adipocyte browning
Postępy Higieny i Medycyny Doświadczalnej, 2018 The data consistently suggests that expansion and activation of beige/brite adipose tissue may possibly serve as a novel cure for obesity and obesity-related complications. Interestingly, besides well-known agents affecting adipocyte transformation, such as cold-induced sympathetic stimulation, the vast majority of biological systems (e.g ...
Oskar Wojciech Wiśniewski +2 more
openaire +1 more source