Angiotensin II participates in mitochondrial thermogenic functions via the activation of glycolysis in chemically induced human brown adipocytes. [PDF]
Sci RepTakeda Y, Yoshikawa T, Dai P.
europepmc +1 more source
Ca2+ Depletion in the ER Causes Store-Operated Ca2+ Entry via the TRPC6 Channel in Mouse Brown Adipocytes. [PDF]
Physiol ResHayato R, Matsumoto T, Higure Y.
europepmc +1 more source
Related searches:
Direct action of capsaicin in brown adipogenesis and activation of brown adipocytes
Cell Biochemistry and Function, 2016The ingestion of capsaicin, the principle pungent component of red and chili peppers, induces thermogenesis, in part, through the activation of brown adipocytes expressing genes related to mitochondrial biogenesis and uncoupling such as peroxisome proliferator‐activated receptor (Ppar) γ coactivator‐1α (Pgc‐1α) and uncoupling protein 1 (Ucp1 ...
Osamu Hashimoto +2 more
exaly +3 more sources
Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel Adipokines [PDF]
Molecular and Cellular Proteomics, 2018 The adipose organ, including white and brown adipose tissues, is an important player in systemic energy homeostasis, storing excess energy in form of lipids while releasing energy upon various energy demands.
Jeroen Krijgsveld +2 more
exaly +2 more sources
Isolation and Characterization of Human Brown Adipocytes
2022Brown adipose tissue (BAT) is a thermoregulatory fat with energy-consuming properties. The location and heterogeneity of this tissue makes it complicated to sample before and after interventions in humans, and an in vitro model for mechanistic and molecular studies is therefore of great value.
Scheele, Camilla +2 more
openaire +3 more sources
Brown and brite adipocytes: Same function, but different origin and response [PDF]
Biochimie, 2017 Inducing brown adipocytes in white adipose tissues is a promising target to combat obesity and its related disorders in human beings. This goal has been especially encouraged by new important discoveries of human brown adipose tissues.
Barbara Gawronska-Kozak, Dinh-Toi Chu
exaly +2 more sources
An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes [PDF]
Adipocyte, 2016 Brown adipose tissue is a promising therapeutic target for opposing obesity, glucose intolerance and insulin resistance. The ability to modulate gene expression in mature brown adipocytes is important to understand brown adipocyte function and delineate ...
Jacob Hansen +2 more
exaly +3 more sources
Determinants of brown adipocyte development and thermogenesis
International Journal of Obesity, 2010The brown adipocyte is a thermogenic cell. Its thermogenic potential is conferred by uncoupling protein-1, which 'uncouples' adenosine triphosphate synthesis from energy substrate oxidation. Brown fat cells in so-called classical brown adipose tissue (BAT) share their origin with myogenic factor-5-expressing myoblasts.
D, Richard +4 more
openaire +2 more sources
MicroRNAs involved in the browning process of adipocytes
Journal of Physiology and Biochemistry, 2015The present review focuses on the role of miRNAs in the control of white adipose tissue browning, a process which describes the recruitment of adipocytes showing features of brown adipocytes in white adipose tissue. MicroRNAs (miRNAs) are a class of short non-coding RNAs (19-22 nucleotides) involved in gene regulation.
N, Arias +7 more
openaire +2 more sources