Results 241 to 250 of about 39,242 (266)

Genetic Studies of Brown Adipocyte Induction

The Journal of Nutrition, 2000
We seek to discover an effective method for utilizing thermogenesis to reduce the caloric load in obese individuals. Experimental evidence indicates that nonshivering thermogenesis is the most effective cellular and biochemical mechanism known for reducing excessive adiposity. In this presentation, we describe our experiments aimed at understanding how
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Trans-anethole ameliorates obesity via induction of browning in white adipocytes and activation of brown adipocytes

Biochimie, 2018
To treat obesity, suppression of white adipose tissue (WAT) expansion and activation of brown adipose tissue (BAT) are considered as potential therapeutic targets. Recent advances have been made in the induction of brown fat-like adipocytes (beige) in WAT, which represents an attractive potential strategy for the management and treatment of obesity ...
Nam Hyeon, Kang, Sulagna, Mukherjee, Taesun, Min, Sun Chul, Kang, Jong Won, Yun   +4 more
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Functional differentiation of white and brown adipocytes

BioEssays, 1997
AbstractAdipose tissue plays an important role in mammalian energy equilibrium not only as a lipid‐dissipating, i.e. energy‐storing, tissue (white adipose tissue), but also as an energy‐dissipating one (brown adipose tissue). Brown adipocytes have the ability of facultative heat production due to a unique mitochondrial protein, the uncoupling protein ...
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Succinate Oxidation in Hamster Brown Adipocytes

1978
In a suspension of isolated hamster brown adipocytes succinate can be oxidized at a high rate. This oxidation capacity is found to be mainly extracellular and can be totally blocked by the SH-reagent DTNB. In the intact cell succinate is found to be oxidized very slow probably as a function of a low transport rate over the membrane(s).
B, Pettersson, P, Lundberg, V S, Bernson
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Huang-Qi San ameliorates hyperlipidemia with obesity rats via activating brown adipocytes and converting white adipocytes into brown-like adipocytes

Phytomedicine, 2020
Brown adipose tissue (BAT) activation is a promising therapeutic target to treat hyperlipidemia with obesity. Huang-Qi San (HQS), an traditional Chinese medicine, can ameliorate hyperlipidemia with obesity, but its mechanism of action (MOA) is not understood.To articulate the MOA for HQS with animal models.The main chemical constituents of HQS were ...
Mengjiao Hao, Zhuoji Guan, Ying Gao, Juling Xing, Xinxin Zhou, Chunyi Wang, Jun Xu, Weimin Li   +7 more
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White adipocytes transdifferentiation into brown adipocytes induced by triiodothyronine

2008
The uncontrolled expansion of white adipose tissue (WAT) seen in obesity predisposes affected individuals to health complications. Another type of fat, brown adipose tissue (BAT) has an opposing physiological function because it allows dissipation instead of storage of energy.
A. Korac, M. Cakic-Milosevic, M. Ukropina, M. Grubic, K. Micunovic, V. Petrovic, B. Buzadzic, A. Jankovic, A. Vasilijevic, B. Korac   +9 more
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Serotonin prevents differentiation into brown adipocytes and induces transdifferentiation into white adipocytes

International Journal of Obesity, 2017
Serotonin is synthesized by many cells in the periphery to affect vasoconstriction, intestinal motility, and glucose and lipid metabolism. It has recently been shown that serotonin leads to fat accumulation in white adipose tissue (WAT). However, the direct effect of serotonin on brown adipose tissue differentiation and metabolism is limited. Therefore,
S, Rozenblit-Susan, N, Chapnik, O, Froy
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AcroBATics: how dying brown adipocytes trigger browning

Nature Reviews Endocrinology, 2022
Julia Zinngrebe, Pamela Fischer-Posovszky   +1 more
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Proteomic differences between white and brown adipocytes

Amino Acids, 2014
Although a series of protein levels from several protein pathways have been shown to differ between white (WA) and brown (BA) adipocytes, proteomic work on this subject with the exception of mitochondrial protein differences is limited. It was, therefore, the aim of the study to compare WA with BA soluble protein levels. Proteins were extracted from WA
Wei-Qiang, Chen, Lin, Li, Gert, Lubec
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Glycogen involved in browning of adipocytes

Nature Reviews Endocrinology, 2021
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