Results 111 to 120 of about 1,575,823 (250)
Over the past 25 years, adipose tissue has emerged as an organ comprising nearly 20 major cell types, including three types of adipocyte subtypes: white, brown, and beige.
Alexander Braunsperger +5 more
doaj +1 more source
Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao +3 more
wiley +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik +3 more
wiley +1 more source
What Fat Is That? Scanning Perirenal Fat: A Survey of Australasian Sonographers
What fat is that? Ultrasound measurement of perirenal adipose tissue and CVD. Results of a survey of Australasian sonographers 2024. ABSTRACT Introduction Ultrasound measures of perirenal adipose tissue (PRAT) have emerged as potentially efficient, cost‐effective, and accessible methods for assessing cardiovascular disease (CVD) risk.
Victoria Baumann +2 more
wiley +1 more source
Perspectives of High‐Resolution Mass Spectrometry in Soil Science
ABSTRACT Soil biogeochemical research requires specific, sensitive, and accurate methods to identify and quantify organic molecules in order to trace biochemical processes and assess element cycling in complex, heterogenous systems. High‐resolution mass spectrometry (HRMS) has evolved into a transformative tool for unraveling the complex chemical ...
Bruno Glaser +11 more
wiley +1 more source
Three years with adult human brown adipose tissue
The presence of active brown adipose tissue in adult humans has been recognized in general physiology only since 2007. The intervening three years established that the depots originally observed by (18)F-fluoro-deoxy-glucose positron emission tomography (
Nedergaard, Jan, +5 more
core +1 more source
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid +8 more
wiley +1 more source
Brown adipose tissue and its therapeutic potential
Obesity and related diseases are a major cause of human morbidity and mortality and constitute a substantial economic burden for society. Effective treatment regimens are scarce, and new therapeutic targets are needed.
Enerbäck, Sven, +2 more
core +1 more source
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen +2 more
wiley +1 more source

