Results 181 to 190 of about 1,390,341 (404)

Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease

open access: yesExperimental Physiology
Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine ...
Anna Malicka   +3 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes. [PDF]

open access: yes, 2019
Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to ...
Ahn, In Sook   +15 more
core   +1 more source

Cold-activated brown adipose tissue in healthy men.

open access: yesNew England Journal of Medicine, 2009
W. D. van Marken Lichtenbelt   +7 more
semanticscholar   +1 more source

Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC

open access: yesEuropean Journal of Heart Failure, EarlyView.
The diagnosis of atrial cardiomyopathy (AtCM) requires electrical atrial dysfunction, with evidence of either mechanical atrial dysfunction, atrial enlargement, or excessive atrial fibrosis. The diagnostic cut‐points presented are for standard electrocardiogram and echocardiogram studies (see Figure 1 for further detail).
Jerremy Weerts   +26 more
wiley   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Two-step regulation by matrix Gla protein in brown adipose cell differentiation

open access: yesMolecular Metabolism
Objective: Bone morphogenetic protein (BMP) signaling is intricately involved in adipose tissue development. BMP7 together with BMP4 have been implicated in brown adipocyte differentiation but their roles during development remains poorly specified ...
Li Zhang   +10 more
doaj   +1 more source

El greix que aprima [PDF]

open access: yes, 2013
Títol del póster : Brown adipose ...
Medina Dols, Aina   +1 more
core  

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