Results 11 to 20 of about 66,718 (257)
iScience, 2023 Summary: Adipose tissue from pheochromocytoma patients acquires brown fat features, making it a valuable model for studying the mechanisms that control thermogenic adipose plasticity in humans. Transcriptomic analyses revealed a massive downregulation of
Moisés Castellá +18 more
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The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity
Nature Communications, 2020 Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provides ...
Marion Peyrou +10 more
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Journal of Lipid Research, 1996 Lipoprotein lipase (LPL) supplies brown adipose tissue with fatty acids for nonshivering thermogenesis. In brown adipose tissue of the Djungarian hamster we studied i) the molecular mechanisms involved in cold-induced stimulation of LPL activity, ii) the
M Klingenspor +6 more
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Brown Adipose Tissue in a Newborn [PDF]
Baylor University Medical Center Proceedings, 2008 A premature infant boy of 35 weeks and 4 days weighing 2605 g was found to have bilateral supraclavicular masses at 13 days of life. He had persistent pulmonary hypertension of the newborn and thrombocytopenia. Delivery was by cesarean section for nonreassuring fetal status, and Apgar scores were 5 at 1 minute and 8 at 5 minutes. Initial radiographs
Brett W, Carter, William G, Schucany
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Di-san junyi daxue xuebao, 2019 Objective To study the changes in the metabolic activity of brown adipose tissues in a mouse model of progeria using Cerenkov luminescence imaging. Methods 18F-FDG PET/CT imaging and Cerenkov luminescence imaging were used to dynamically monitor the ...
WANG Zhengjie +4 more
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Brown adipose tissue and thermogenesis [PDF]
Hormone Molecular Biology and Clinical Investigation, 2014 Abstract The growing understanding of adipose tissue as an important endocrine organ with multiple metabolic functions has directed the attention to the (patho)physiology of distinct fat depots. Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate ...
Anna, Fenzl, Florian W, Kiefer
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Bioengineering beige adipose tissue therapeutics
Frontiers in Endocrinology, 2015 Unlocking the therapeutic potential of brown/beige adipose tissue requires technological advancements that enable the controlled expansion of this uniquely thermogenic tissue.
Kevin eTharp, Andreas eStahl
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Roles of FGFs as adipokines in adipose tissue development, remodeling, and metabolism
Frontiers in Endocrinology, 2014 White and brown adipose tissues, which store and burn lipids, respectively, play critical roles in energy homeostasis. Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, and neural function. Among
Nobuyuki eItoh, Hiroya eOhta
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Scientific Reports, 2021 Brown adipose tissue function declines during aging and may contribute to the onset of metabolic disorders such as diabetes and obesity. Only limited understanding of the mechanisms leading to the metabolic impairment of brown adipocytes during aging ...
Carola Mancini +5 more
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Recent progress in the study of brown adipose tissue
Cell & Bioscience, 2011 Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat.
Yao Xuan +3 more
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