Results 281 to 290 of about 1,390,341 (404)

The beneficial effects of brown adipose tissue transplantation.

Molecular Aspects of Medicine, 2019
Joseph D. White, Revati S. Dewal, K. Stanford   +2 more
semanticscholar   +1 more source

Lung‐Derived Small Extracellular Vesicles Containing miR‐15a‐5p/miR‐96‐5p Promote Myocardial Fibrosis in Hypertrophic Cardiomyopathy via Targeting SMAD7

Small, EarlyView.
Small extracellular vesicles (sEVs) are critical regulators of inter‐tissue communication in cardiovascular diseases. In this study, it is found that lung‐derived sEVs enhance cardiac fibroblasts activation and aggravates myocardial fibrosis progression in hypertrophic cardiomyopathy (HCM). sEVmiR‐15a‐5p and sEVmiR‐96‐5p exert this effect via targeting
Minwen Long, Jinpeng Sun, Dongli Zhou, Can Chen, Jiangcheng Shu, Xiaobo Mao, Kunwu Yu, Minglu Liang, Long Chen, Yumei Wang, Min Cheng   +10 more
wiley   +1 more source

YTHDC1 promotes postnatal brown adipose tissue development and thermogenesis by stabilizing PPARγ. [PDF]

EMBO J
Wang L, Wang Y, Ding K, Li Z, Zhang Z, Li X, Song Y, Xie L, Chen Z.   +8 more
europepmc   +1 more source

Dual‐Targeted Glucose‐Dependent Insulinotropic Polypeptide‐Loaded Photothermal Nanoparticles to Prevent Obesity via Lipolysis and Browning of White Adipose Tissue

Small Science, EarlyView.
Current weight‐loss medications inevitably cause adverse effects such as depression or muscle loss. The developed GIP/ICG@P/R8 NPs specifically promoted energy expenditure by inducing browning, lipolysis and apoptosis of WAT in vitro and in vivo. The results showed a 9.23% weight reduction after 14 days, enhanced insulin sensitivity, improved fatty ...
Ting Xie, Lutang Zhao, Shurui Pei, Kaikai Wen, Sijia Fei, Wan Chen, Zhengyang Li, Long Zhang, Linlin Li, Lixin Guo, Hui Huang, Qi Pan   +11 more
wiley   +1 more source

Thermoneutral housing worsens MASLD and reveals defective brown adipose tissue response to β3-adrenergic stimulation. [PDF]

iScience
Martin CMP, Polizzi A, Alquier-Bacquié V, Huillet M, Rives C, Dauriat CJG, Bruse J, Melin V, Naylies C, Lippi Y, Lasserre F, Wan J, Flores-Flores R, Bertrand-Michel J, Blas-Y-Estrada F, Rousseau-Bacquié E, Levade T, Rémignon H, Langin D, Mouisel E, Lotersztajn S, Chassaing B, Gamet-Payrastre L, Guillou H, Ellero-Simatos S, Fougerat A, Loiseau N.   +26 more
europepmc   +1 more source

Brown adipose tissue and diet-induced thermogenesis

, 1981
G. R. Hervey, G. Tobin
openalex   +1 more source

Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin.

Cell Metabolism, 2018
X. Kong, Ting Yao, P. Zhou, L. Kazak, Danielle E. Tenen, A. Lyubetskaya, Brian A. Dawes, Linus T. Tsai, B. Kahn, B. Spiegelman, Tiemin Liu, E. Rosen   +11 more
semanticscholar   +1 more source

Harbingers of change: Towards a mechanistic understanding of anticipatory plasticity in animal systems

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Phenotypic plasticity is a strategy by which animals alter behaviour, morphology and/or physiology in response to cues of current conditions to cope with environmental heterogeneity.
Lauren Petrullo, Natalie J. Morris, Chloé Tharin, Ben Dantzer   +3 more
wiley   +1 more source

Seasonal body mass dynamics mediate life‐history trade‐offs in a hibernating mammal

Journal of Animal Ecology, EarlyView.
We tested a suite of ecological hypotheses to explain variation in seasonal body mass dynamics of a fat‐storing mammalian hibernator. We further demonstrated that pre‐hibernation mass gain in ground squirrels mediates an annual allocation trade‐off between current and future reproduction as the squirrels forage and rear young under predation risk ...
Austin Z. T. Allison, Courtney J. Conway, Amanda R. Goldberg, Alice E. Morris, Emma C. Hakanson   +4 more
wiley   +1 more source

Vascular Endothelial NAMPT‐Mediated NAD+ Biosynthesis Regulates Angiogenesis and Cardiometabolic Functions in Male Mice

Aging Cell, EarlyView.
Using male vascular endothelial cell–specific Nampt knockout and naturally aged mice, we identified endothelial NAD+ deficiency as a central driver of age‐related angiogenic failure, impaired subcutaneous adipogenesis, and cardiometabolic dysfunction.
Shotaro Kosugi, Shintaro Yamaguchi, Ken Nishioka, Taichi Nagahisa, Yasuhiro Watanabe, Daiki Kojima, Kenji Kaneko, Ryunosuke Mitsuno, Ran Nakamichi, Yoshinaga Kawano, Kenichiro Kinouchi, Koichiro Homma, Takeshi Kanda, Junichiro Irie, Kazutoshi Miyashita, Toshiaki Monkawa, Jun Yoshino, Hiroshi Itoh, Kaori Hayashi   +18 more
wiley   +1 more source