Results 311 to 320 of about 1,390,341 (404)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Single-nucleus mRNA-sequencing reveals dynamics of lipogenic and thermogenic adipocyte populations in murine brown adipose tissue in response to cold exposure. [PDF]

Mol Metab
Behrens J, Wang T, Kilian C, Worthmann A, Herman MA, Heeren J, Adlung L, Scheja L.   +7 more
europepmc   +1 more source

Mechanisms of decreasing effect of intracerebroventricular administration of thyrotropin-releasing hormone on blood flow to the brown adipose tissue in rats

, 1985
Yoko Uchida, Teruko Nomoto
openalex   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Akebia Saponin D Targeting Ubiquitin Carboxyl-Terminal Hydrolase 4 Promotes Peroxisome Proliferator-Activated Receptor Gamma Deubiquitination and Activation of Brown Adipose Tissue Thermogenesis in Obesity. [PDF]

MedComm (2020)
Chen L, Liu DH, Li YX, Yang S, Jia WH, Peng L, Liu HL, Wang XB, Hu B, Wang YC, Pan C, Lusis AJ, Liu LH, Gong LL.   +13 more
europepmc   +1 more source

Thermogenic Capacity of Brown Adipose Tissue Is Reduced in Rats Fed a High Protein, Carbohydrate-Free Diet

, 1992
Márcia N. Brito, Nilton A. Brito, Renato H. Migliorini   +2 more
openalex   +1 more source

Body surface temperatures as biomarkers of physiological environmental adaptation in wild birds and mammals

Biological Reviews, EarlyView.
ABSTRACT The ability of individuals to cope with their environment, and therefore the likelihood that they survive and pass on their genes (i.e. fitness), is largely determined by physiological state. Tracking physiological state in wild animals, however, is challenging.
Paul Jerem, L. Michael Romero
wiley   +1 more source

Amino Acid-Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis. [PDF]

Adv Sci (Weinh)
Luo P, Tong K, Gan Y, Tang M, Niu Y, Liu K, Ni S, Wu S, Jiang X, Jiang H, Xiao F, Chen S, Lv W, Li X, Yuan F, Guo F.   +15 more
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source