Results 331 to 340 of about 1,390,341 (404)

Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific

The FEBS Journal, EarlyView.
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty, Raz Ben‐David, Shenhav Shemer   +2 more
wiley   +1 more source

Mitochondrial fission is required for thermogenesis in brown adipose tissue. [PDF]

PLoS One
Ibayashi Y, Hasuzawa N, Nomura S, Kabashima M, Nagayama A, Iwata S, Kitamura M, Ashida K, Moriyama Y, Yamamoto K, Nomura M, Wang L.   +11 more
europepmc   +1 more source

Wild and Naturalized Hatchery Brown Trout: A Comparison of Movement, Space Use, and Survival in a Large Lake

Fisheries Management and Ecology, EarlyView.
ABSTRACT Most research comparing wild and hatchery‐produced fish focuses on recently stocked individuals. As a result, these studies only investigate the behavior of naive hatchery fish, leaving a knowledge gap regarding long‐term survivors. We compared the movement, space use, and survival of wild and hatchery‐reared brown trout (Salmo trutta) that ...
Daniel Palm, Jack A. Brand, Petter Lundberg, James P. Losee, Tomas Brodin, Michael G. Bertram, Gustav Hellström   +6 more
wiley   +1 more source

Evaluating the UCP1 expression of brown adipose tissue by quantifying hepatic inflammation using synthetic magnetic resonance imaging: an experimental study with a mouse model. [PDF]

Quant Imaging Med Surg
Dong Z, Li L, Huo M, Zhang Y, Zhou X, Tang M, Peng Z, Cui W, Liu J, Wang J, Cai H, Feng ST, Li Y, Luo Y.   +13 more
europepmc   +1 more source

Modelling of the Systemic Inflammatory Host Response in Relation to the Microbiome of the Endodontic Infection

International Endodontic Journal, EarlyView.
ABSTRACT Aim This study aimed to investigate systemic inflammatory responses in individuals with apical periodontitis (AP) compared to age‐matched healthy controls, using advanced multiway modelling techniques. We examined associations between inflammatory mediators, age, gender, symptomatic status, and the microbial composition and function to better ...
A. C. Georgiou, G. R. van der Ploeg, J. A. Westerhuis, S. V. van der Waal, A. Heintz‐Buschart, A. K. Smilde, B. W. Brandt   +6 more
wiley   +1 more source

Brown adipose tissue transplantation ameliorates hindlimb ischemic damage in diabetic mice. [PDF]

Sci Rep
Lu T, Liu A, Li C, Li Y, Yang B, Liu Q, Jiang H.   +6 more
europepmc   +1 more source

Exposure to Metal Mixtures and Childhood Adiposity: An Examination of Periods of Heightened Susceptibility Between Gestation and Late Childhood

Pediatric Obesity, EarlyView.
ABSTRACT Introduction Childhood obesity is a public health concern. Studies have investigated the effects of metal mixtures on childhood obesity but none have identified periods of heightened susceptibility of exposure. We identified the periods by investigating the association of metal mixture, measured at four time points, with adiposity.
Janice M. Y. Hu, Michael M. Borghese, Mandy Fisher, Joseph M. Braun, Katherine M. Morrison, Mark R. Palmert, Linda Booij, Constadina Panagiotopoulos, Jillian Ashley‐Martin   +8 more
wiley   +1 more source

Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis. [PDF]

Nat Commun
Cicuéndez B, Mora A, López JA, Curtabbi A, Pérez-García J, Porteiro B, Jimenez-Blasco D, Latorre-Muro P, Vo P, Jerome M, Gómez-Santos B, Romero-Becerra R, Leiva M, Rodríguez E, León M, Leiva-Vega L, Gómez-Lado N, Torres JL, Hernández-Cosido L, Aguiar P, Marcos M, Jastroch M, Daiber A, Aspichueta P, Bolaños JP, Spinelli JB, Puigserver P, Enriquez JA, Vázquez J, Folgueira C, Sabio G.   +30 more
europepmc   +1 more source

Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Detecting selection footprints offers valuable insight into evolutionary processes and the mechanisms underlying phenotypic diversity in selected traits. Domestication, natural and artificial selection, and breeding have produced indigenous goats well‐adapted to their local environments, making them crucial genetic resources. Understanding the
Sang Van Le, Panoraia Alexandri, Julius H.J. van der Werf, Luisa Olmo, Stephen W. Walkden‐Brown, Sara de Las Heras‐Saldana   +5 more
wiley   +1 more source