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Recent progress in the study of brown adipose tissue [PDF]
Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat.
Yao Xuan+3 more
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Assessment of brown adipose tissue function [PDF]
In this review we discuss practical considerations for the assessment of brown adipose tissue in rodent models, focusing on mice. The central aim of the review is to provide a critical appraisal of the utility of specialised techniques for assessing ...
Samuel eVirtue+2 more
doaj +4 more sources
Brown and Beige Fat: Therapeutic Potential in Obesity [PDF]
BACKGROUND: The epidemic of obesity and type 2 diabetes presents a serious challenge to scientific and biomedical communities worldwide. There has been an upsurge of interest in the adipocyte coincident with the onset of the obesity epidemic and the ...
Anna Meiliana, Andi Wijaya
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Obesity is currently a global pandemic, and is associated with increased mortality and co-morbidities including many metabolic diseases. Obesity is characterized by an increase in adipose mass due to increased energy intake, decreased energy expenditure,
Townsend, Kristy L, Tseng, Yu-Hua
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Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue [PDF]
Background Obesity has become a critical public health challenge worldwide. Prioritizing prevention and tackling root causes—rather than merely managing symptoms—is critical to curbing this pandemic.
Zhiqi Huang+14 more
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Overweight and obesity have become a world-wide problem. However, effective intervention approaches are limited. Brown adipose tissue, which helps maintain body temperature and contributes to thermogenesis, is dependent on uncoupling protein1.
Xiaomeng Liu+7 more
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Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue
Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann+14 more
doaj +1 more source
miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit [PDF]
Brown adipocytes are a primary site of energy expenditure and reside not only in classical brown adipose tissue but can also be found in white adipose tissue.
Chen, Y.+6 more
core +1 more source
The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity
Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provides ...
Marion Peyrou+10 more
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Brown adipose tissue monocytes support tissue expansion
Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose tissue immune cells and describe multiple macrophage and monocyte subsets and ...
Alexandre Gallerand+26 more
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