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FoodsCapsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang +5 more
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Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency
EBioMedicine, 2019 Background: Inflammation is the most relevant mechanism linking obesity with insulin-resistance and metabolic disease. It impacts the structure and function of tissues and organs involved in metabolism, such as the liver, pancreatic islets and the ...
José C. de-Lima-Júnior +19 more
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iScience, 2023 Summary: Adipose tissue from pheochromocytoma patients acquires brown fat features, making it a valuable model for studying the mechanisms that control thermogenic adipose plasticity in humans. Transcriptomic analyses revealed a massive downregulation of
Moisés Castellá +18 more
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Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.
Molecules and Cells, 2019 Brown adipose tissue (BAT) is rich in mitochondria and plays important roles in energy expenditure, thermogenesis, and glucose homeostasis. We find that levels of mitochondrial protein succinylation and malonylation are high in BAT and subject to ...
Guoxiao Wang +8 more
semanticscholar +1 more source
Brown adipose tissue and bone [PDF]
International Journal of Obesity Supplements, 2015 Brown adipose tissue (BAT) is capable of transforming chemically stored energy, in the form of triglycerides, into heat. Recent studies have shown that metabolically active BAT is present in a large proportion of adult humans, where its activity correlates with a favorable metabolic status. Hence, the tissue is now regarded as an interesting target for
M E, Lidell, S, Enerbäck
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Journal of Lipid Research, 1994 Brown adipose tissue and collagenase-isolated brown adipocytes were investigated in rats by means of 1H and 13C nuclear magnetic resonance spectroscopy.
C Zancanaro +5 more
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Roles of FGFs as adipokines in adipose tissue development, remodeling, and metabolism
Frontiers in Endocrinology, 2014 White and brown adipose tissues, which store and burn lipids, respectively, play critical roles in energy homeostasis. Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, and neural function. Among
Nobuyuki eItoh, Hiroya eOhta
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The effect of estrogen on brown adipose tissue activity in male rats
BMC Research Notes, 2022 Objective Centrally administered estrogen can increase sympathetic nerve activity to brown adipose tissue, resulting in thermogenesis. The central thermogenic effects of estrogen have not been investigated in males.
W. Sievers +7 more
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Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans
Cell Death and Disease, 2019 Brown adipose tissue (BAT) dissipates metabolic energy and mediates non-shivering thermogenesis, thereby boosting energy expenditure. Increasing BAT mass and activity is expected to be a promising strategy for combating obesity; however, few medications ...
Lingyan Wu +12 more
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Brown adipose tissue and thermogenesis [PDF]
Hormone Molecular Biology and Clinical Investigation, 2014 Abstract The growing understanding of adipose tissue as an important endocrine organ with multiple metabolic functions has directed the attention to the (patho)physiology of distinct fat depots. Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate significant amounts of chemical energy through uncoupled ...
Anna, Fenzl, Florian W, Kiefer
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