Results 211 to 220 of about 178,401 (255)
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Brown adipose tissue

2022
The role of brown adipose tissue in humans is still a matter of debate: Does it play a substantial role in metabolic diseases, or not? The settling of this discussion requires clinical trials, generally including noninvasive imaging techniques, in order to assess the metabolic activity of brown adipose tissue.
Paulus, Andreas, Bauwens, Matthias
openaire   +2 more sources

Brown Adipose Tissue Transplantation

2023
The metabolic benefits of brown adipose tissue (BAT) are well known. Increasing the BAT content and/or activity is a proposed therapeutic approach to combat metabolic disease. Activation and induction of endogenous BAT have achieved varying degrees of success in correcting obesity, insulin resistance, and cardiovascular disease, with some limitations ...
openaire   +2 more sources

Brown adipose tissue and aging

Current Opinion in Clinical Nutrition and Metabolic Care, 2011
Brown adipose tissue (BAT) was thought to be a tissue with physiological importance early in life (maintenance of body temperature) and to disappear after birth. Recent studies using functional imaging have identified the presence of BAT activity throughout life.
Lecoultre Virgile, Ravussin Eric
openaire   +2 more sources

The Genetics of Brown Adipose Tissue

2010
Brown adipose tissue is highly differentiated and has evolved as a mechanism for heat production based upon uncoupling of mitochondrial oxidative phosphorylation. Additionally, large amounts of lipid can be stored in the cells to provide fuel necessary for heat production upon adrenergic stimulation from the central nervous system, and a highly ...
Leslie P, Kozak, Robert A, Koza
openaire   +2 more sources

The Origins of Brown Adipose Tissue

New England Journal of Medicine, 2009
Adipocytes that make up brown fat have two disparate lineages; one seems more closely related to muscle than to white adipose tissue.
openaire   +2 more sources

cGMP and Brown Adipose Tissue

2015
The second messenger cyclic guanosine monophosphate (cGMP) is a key mediator in physiological processes such as vascular tone, and its essential involvement in pathways regulating metabolism has been recognized in recent years. Here, we focus on the fundamental role of cGMP in brown adipose tissue (BAT) differentiation and function.
Linda S, Hoffmann   +2 more
openaire   +2 more sources

Brown Adipose Tissue. Interscapular Brown Adipose Tissue of the Rat

1985
Brown or multilocular adipose tissue is relatively infrequent in man and is found predominantly in newborns. It occurs in the neck, armpit (Fig. A1), in the vicinity of the subclavian artery (Fig. A2) and kidney (Fig.A3), dorsal skin, mediastinum (Fig. A4), and mesenteries.
openaire   +1 more source

Brown adipose tissue in humans

International Journal of Obesity, 2010
Obesity is endemic in many regions of the world and a forerunner of several serious and sometimes fatal diseases such as ischemic heart disease, stroke, kidney failure and neoplasia. Although we know its origin--it results when energy intake exceeds energy expenditure--at present, the only proven therapy is bariatric surgery.
openaire   +2 more sources

Brown Adipose Tissue

2017
Brown adipose tissue shows accumulation of FDG in normal fat tissue on PET/MR imaging that can be confusing to the inexperienced reader. Comparison of the fused PET/MR images with non-fused MR images helps differentiate brown fat from true lesions.
Jan Nedergaard, Barbara Cannon
  +4 more sources

Brown Adipose Tissue

2010
Brown adipose tissue is structurally and functionally different from white adipose tissue. Although abundant at birth, in the adult it exists only as small depots at specific locations such as the interscapular region of rodents. The brown colour of the tissue is due to an abundance of mitochondria.
Margit Pavelka, Jürgen Roth
openaire   +1 more source

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