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cGMP and Brown Adipose Tissue

2015
The second messenger cyclic guanosine monophosphate (cGMP) is a key mediator in physiological processes such as vascular tone, and its essential involvement in pathways regulating metabolism has been recognized in recent years. Here, we focus on the fundamental role of cGMP in brown adipose tissue (BAT) differentiation and function.
Linda S, Hoffmann   +2 more
openaire   +2 more sources

Brown Adipose Tissue

2010
Brown adipose tissue is structurally and functionally different from white adipose tissue. Although abundant at birth, in the adult it exists only as small depots at specific locations such as the interscapular region of rodents. The brown colour of the tissue is due to an abundance of mitochondria.
Margit Pavelka, Jürgen Roth
openaire   +1 more source

Brown adipose tissue thermogenesis

Physiology
Human brown adipose tissue (BAT) has emerged as a metabolically dynamic organ with the potential to influence thermoregulation, substrate utilization, and cardiometabolic health. This review synthesizes current knowledge on the biomolecular features of human BAT, physiological and pharmacological strategies to stimulate energy ...
openaire   +2 more sources

Brown adipose tissue in humans

International Journal of Obesity, 2010
Obesity is endemic in many regions of the world and a forerunner of several serious and sometimes fatal diseases such as ischemic heart disease, stroke, kidney failure and neoplasia. Although we know its origin--it results when energy intake exceeds energy expenditure--at present, the only proven therapy is bariatric surgery.
openaire   +2 more sources

Brown adipose tissue mitochondria

Biochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, 1975
T, Flatmark, J I, Pedersen
openaire   +2 more sources

Thermogenesis in Brown Adipose Tissue

New England Journal of Medicine, 1985
T B, Seaton, S, Welle, R G, Campbell
openaire   +2 more sources

An update on brown adipose tissue biology: a discussion of recent findings

American Journal of Physiology - Endocrinology and Metabolism, 2021
Rafael Calais Gaspar   +2 more
exaly  

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