Results 211 to 220 of about 172,968 (298)

Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming

Obesity Reviews, EarlyView.
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos, Fabíola Isabel Suano de Souza, Luciana P. Pisani   +2 more
wiley   +1 more source

Myeloid GHSR Deficiency Protects Against Thermogenic Impairment in Aging Through Immune Remodeling of Brown Adipose Tissue. [PDF]

Cells
Han HW, Kim DM, Baratiboldaji R, Wang H, Liu Z, Shen Z, Jha DK, Teferra T, Septiningsih EM, Patil B, Sun Y.   +10 more
europepmc   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Adipocyte Leptin Signaling Regulates Glycemia and Cardiovascular Function by Enhancing Brown Adipose Tissue Thermogenesis in Obese Male Mice. [PDF]

Diabetes
Ono Y, Kennard S, Wall BT, Ma J, Belin de Chantemèle EJ.   +4 more
europepmc   +1 more source

Effects of Glucagon‐Like Peptide‐1 Receptor Agonists (Mono and Combination Therapy) on Energy Expenditure: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat‐free mass and fat mass losses) and mass‐independent adaptations in EE (e.g., hormones). Glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are indicated for obesity management; however, their effects on EE remain unclear ...
Flavio T. Vieira, ZhiDi Deng, Manfred J. Muller, Giovanna G. L. Bergamasco, Sarah Cawsey, Melania Manco, Steven B. Heymsfield, Carla M. Prado, Andrea M. Haqq   +8 more
wiley   +1 more source

A paraventricular hypothalamic control of social stress susceptibility by targeting brown adipose tissue β3 adrenoceptor. [PDF]

Commun Biol
Du X, Zhang J, Wang Q, Zhou D, Zhang W, Song L, Cui M, Ge T, Zhai X, Yu Y, Yang J, Hu A, Zhang H, Cao JL, Wu Z.   +14 more
europepmc   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source

Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue. [PDF]

EMBO Rep
Jaeckstein MY, Fischer AW, Rissiek B, Staehler T, Heine M, Behrens J, Mann O, Pfeifer A, Magnus T, Schlein C, Worthmann A, Scheja L, Koch-Nolte F, Heeren J.   +13 more
europepmc   +1 more source

GLP‐1 Receptor Agonists and Weight Loss: A Critical Review of Mechanisms

Obesity Reviews, EarlyView.
ABSTRACT GLP‐1 receptor agonist medications have the potential to promote marked weight loss, but maximal and sustained benefit may be compromised by poor compliance and cessation of use. Development of next‐generation medications that address current obstacles to effective use and development of effective adjunct treatments will benefit from better ...
Giorgia Rutigliani, Tzu‐Wen L. Cross, Erica de Jong, Emily S. Glover, Ivan D. Mendoza, Mojisola Adisa, Keigo Tomoo, Xinyi Zhou, Richard D. Mattes   +8 more
wiley   +1 more source

11-Oxygenated Androgens Inhibit Brown Adipose Tissue Differentiation.

Endocrinology
Yuan Y, Steenbergen J, de Oliveira Santos Goulart A, Sabaté-Pérez A, Visser JA.   +4 more
europepmc   +1 more source