Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming [PDF]
, 2017 BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in
Czech, Michael P +11 more
core +4 more sources
Does Adipose Tissue Thermogenesis Play a Role in Metabolic Health?
Journal of Obesity, 2013 The function ascribed to brown adipose tissue in humans has long been confined to thermoregulation in neonates, where this thermogenic capacity was thought lost with maturation.
Craig Porter +2 more
doaj +1 more source
The effects of resistance training, testosterone and palm (Phoenix dactylifera L.) pollen extract on the expression of FNDC5 and IGF1 genes in brown adipose tissue in male rats [PDF]
مجله علوم پزشکی فیض (پیوسته), 2023 Background and Aim: The use of testosterone enanthate is popular among athletes, especially resistance sports. Considering the side effects of using testosterone enanthate, it seems necessary to find alternative methods.
Ali Arbati +3 more
doaj
Journal of Ovarian Research, 2023 Background Traditional Chinese medicine has been used for a long time to treat a variety of gynecological diseases. Among various traditional Chinese medicine, Dingkun Pill (DK) has been used for the treatment of female gynecological diseases.
Mengqing Gu +9 more
doaj +1 more source
Casein Kinase 2—A Kinase that Inhibits Brown Fat Formation [PDF]
, 2015 In adipose tissue, there is a delicate balance between storing and expending energy. In this issue, Shinoda et al. (2015) use phosphoproteomics to identify casein kinase 2 (CK2) as a suppressor of brown adipocyte formation, providing insights into how ...
Enerbäck, Sven
core +1 more source
PVAT and Its Relation to Brown, Beige, and White Adipose Tissue in Development and Function
Frontiers in Physiology, 2018 Adipose tissue is commonly categorized into three types with distinct functions, phenotypes, and anatomical localizations. White adipose tissue (WAT) is the major energy store; the largest depots of WAT are found in subcutaneous or intravisceral sites ...
Staffan Hildebrand +2 more
doaj +1 more source
The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms [PDF]
, 2015 Objectives: The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.
Clark, S. +10 more
core +3 more sources
Early Overfeed-Induced Obesity Leads to Brown Adipose Tissue Hypoactivity in Rats
Cellular Physiology and Biochemistry, 2013 Background/Aims: Brown adipose tissue activation has been considered a potential anti-obesity mechanism because it is able to expend energy through thermogenesis. In contrast, white adipose tissue stores energy, contributing to obesity.
Douglas L. de Almeida +7 more
doaj +1 more source
PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]
, 2017 How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M +8 more
core +3 more sources
Nature Communications, 2018 Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and
Chunming Ding +12 more
doaj +1 more source